Biphenylindanone A

Product Name: Biphenylindanone A
CAS No.: 866823-73-6
Chemical Name: Biphenylindanone A
Synonyms: BINA;CS-203;MRLSD 230;BINA, >=98%;Biphenylindanone A;4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid;3'-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid;3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylicacid;[1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-diMethyl-1-oxo-1H-inden-5-yl)oxy]Methyl]-
CBNumber: CB72518270
Molecular Formula: C30H30O4
Formula Weight: 454.56
MOL File: 866823-73-6.mol

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Biphenylindanone A Property

Melting point:: 238-241℃
Boiling point:: 676.9±55.0 °C(Predicted)
Density: 1.220
storage temp.: Desiccate at RT
solubility: DMSO: ≥18mg/mL
pka: 4.17±0.10(Predicted)
form: powder
color: white to tan

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Safety

WGK Germany: 3

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: 5.04463
Product name: BINA - CAS 866823-73-6 - Calbiochem
Packaging: 5mg
Price: $257
Updated: 2023/01/07

Sigma-Aldrich

Product number: B8688
Product name: Biphenyl-indanone A
Purity: ≥98% (HPLC), powder
Packaging: 5mg
Price: $181
Updated: 2022/05/15

Sigma-Aldrich

Product number: B8688
Product name: Biphenyl-indanone A
Purity: ≥98% (HPLC), powder
Packaging: 25mg
Price: $694
Updated: 2022/05/15

Cayman Chemical

Product number: 11986
Product name: Biphenylindanone A
Purity: ≥98%
Packaging: 5mg
Price: $106
Updated: 2024/03/01

Cayman Chemical

Product number: 11986
Product name: Biphenylindanone A
Purity: ≥98%
Packaging: 10mg
Price: $184
Updated: 2024/03/01

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Biphenylindanone A Chemical Properties,Usage,Production

Description

The metabotropic glutamate receptor 2 (mGluR2) is a G_i/o-coupled receptor which is expressed on presynaptic nerve terminals and modulates the release of neurotransmitters like glutamate and GABA. Biphenylindanone A (BINA) is a positive allosteric modulator of mGluR2, stimulating the human and rat receptors with EC₅₀ values of 33.2 and 96 nM, respectively. It has no effect on glutamate-induced activation of other mGluR types. BINA can be used on cells, tissues, or animals. Because of its selectivity for mGluR2, robust in vivo activity, and brain penetrance, BINA can be used to elucidate the role of mGluR2 in such diverse processes as psychosis, schizophrenia, and drug addiction.

Uses

Biphenylindanone A is an orally active metabotropic glutamate subtype 2 receptor positive allosteric modulator.

Definition

ChEBI: Biphenylindanone a is a member of biphenyls.

storage

Room temperature (desiccate)

Biphenylindanone A Preparation Products And Raw materials

Raw materials

Preparation Products

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Biphenylindanone A Suppliers

Canada 1 China 42 India 1 United Kingdom 1 United States 11 Global 56

J & K SCIENTIFIC LTD.

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SPIRO PHARMA

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Shanghai EFE Biological Technology Co., Ltd.

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View Lastest Price from Biphenylindanone A manufacturers

Career Henan Chemical Co

Product: Biphenylindanone A 866823-73-6
Price: US $1.00/KG
Min. Order: 1KG
Purity: 99.0%
Supply Ability: 100kg
Release date: 2020-01-14

866823-73-6, Biphenylindanone ARelated Search:

Biphenylindanone A

3'-[[(2-Cyclopentyl-2,3-dihydro-6,7-dimethyl-1-oxo-1H-inden-5-yl)oxy]methyl]-[1,1'-biphenyl]-4-carboxylicacid

BINA

3'-[[(2-Cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydro-1H-inden-5-yl)oxy]methyl]biphenyl-4-carboxylic acid

MRLSD 230

4-[3-[(2-cyclopentyl-6,7-dimethyl-1-oxo-2,3-dihydroinden-5-yl)oxymethyl]phenyl]benzoic acid

CS-203

[1,1'-Biphenyl]-4-carboxylic acid, 3'-[[(2-cyclopentyl-2,3-dihydro-6,7-diMethyl-1-oxo-1H-inden-5-yl)oxy]Methyl]-

BINA, >=98%

866823-73-6

C30H30O4