ChemicalBook > CAS DataBase List > PS 48

PS 48

Product Name
PS 48
CAS No.
1180676-32-7
Chemical Name
PS 48
Synonyms
PS 48;CS-1466;PS 48;PS-48;PS-48;PS 48;PS48;5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid;(Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid;(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid;2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)-
CBNumber
CB72518801
Molecular Formula
C17H15ClO2
Formula Weight
286.75
MOL File
1180676-32-7.mol
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PS 48 Property

Melting point:
114-115℃
Boiling point:
444.1±24.0 °C(Predicted)
Density 
1.225±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO: >20mg/mL
form 
powder
pka
4.55±0.10(Predicted)
color 
white to off-white
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Safety

WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
P0022
Product name
PS48
Purity
≥98% (HPLC)
Packaging
5mg
Price
$80.4
Updated
2024/03/01
Sigma-Aldrich
Product number
P0022
Product name
PS48
Purity
≥98% (HPLC)
Packaging
25mg
Price
$538
Updated
2024/03/01
TRC
Product number
P839688
Product name
PS48
Packaging
10mg
Price
$85
Updated
2021/12/16
TRC
Product number
P839688
Product name
PS48
Packaging
50mg
Price
$280
Updated
2021/12/16
Usbiological
Product number
463157
Product name
PS 48
Packaging
10mg
Price
$355
Updated
2021/12/16
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PS 48 Chemical Properties,Usage,Production

Uses

PS 48 is a phosphoinositide-dependent protein kinase-1 (PDK1) activator.

Biochem/physiol Actions

PS48 is a PDK1 (phosphoinositide-dependent protein kinase 1) activator which binds to the HM/PIF binding pocket rather than the ATP-binding site. PS48 is one of only a few truly allosteric compounds targeting a regulatory binding site on a protein kinase catalytic domain that is not adjacent to or overlapping with the ATP-binding site.

PS 48 Preparation Products And Raw materials

Raw materials

Preparation Products

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PS 48 Suppliers

China 78 United Kingdom 1 United States 11 Global 90
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View Lastest Price from PS 48 manufacturers

Career Henan Chemical Co
Product
(2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid 1180676-32-7
Price
US $1.00/g
Min. Order
100g
Purity
99%
Supply Ability
G/KG/T
Release date
2019-12-20

1180676-32-7, PS 48Related Search:


  • (2Z)-5-(4-Chlorophenyl)-3-phenyl-2-pentenoicacid
  • 5-(4-Chloro-phenyl)-3-phenyl-pent-2-enoic acid
  • PS 48
  • (Z)-5-(4-Chlorophenyl)-3-phenylpent-2-enoic acid
  • PS 48;PS-48
  • PS-48;PS 48;PS48
  • CS-1466
  • 2-Pentenoic acid, 5-(4-chlorophenyl)-3-phenyl-, (2Z)-
  • 1180676-32-7