AT-56
- Product Name
- AT-56
- CAS No.
- 162640-98-4
- Chemical Name
- AT-56
- Synonyms
- AT 56;CS-1414;AT56/AT-56;AT 56, >=98%;AT-56 AT-7519;4-Dibenzo[a,d]cyclohepten-5-ylidene-1-[4-(2H-tetrazol-5-yl)-butyl]-piperidine;4-Dibenzo[a,d] cyclohepten-5-ylidene-1-[4-(1H-tetrazol-5-yl) butyl] piperdine;4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(1H-tetrazol-5-yl)butyl]piperidine;4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine;Piperidine, 4-(5H-dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-
- CBNumber
- CB72518821
- Molecular Formula
- C25H27N5
- Formula Weight
- 397.52
- MOL File
- 162640-98-4.mol
AT-56 Property
- Boiling point:
- 620.4±65.0 °C(Predicted)
- Density
- 1.216±0.06 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- DMSO: soluble10mg/mL, clear
- form
- powder
- pka
- 4.99±0.10(Predicted)
- color
- white to beige
- InChIKey
- LQNGMDUIRLSESZ-UHFFFAOYSA-N
- SMILES
- N1(CCCCC2=NNN=N2)CC/C(=C2/C3=CC=CC=C3C=CC3=CC=CC=C3/2)/CC1
Safety
- WGK Germany
- 3
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Danger
- Hazard statements
-
H228Flammable solid
H315Causes skin irritation
H319Causes serious eye irritation
- Precautionary statements
-
P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P240Ground/bond container and receiving equipment.
P241Use explosion-proof electrical/ventilating/lighting/…/equipment.
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P337+P313IF eye irritation persists: Get medical advice/attention.
P370+P378In case of fire: Use … for extinction.
N-Bromosuccinimide Price
- Product number
- SML0856
- Product name
- AT-56
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $107
- Updated
- 2024/03/01
- Product number
- SML0856
- Product name
- AT-56
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $419
- Updated
- 2024/03/01
- Product number
- 13160
- Product name
- AT-56
- Purity
- ≥95%
- Packaging
- 1mg
- Price
- $37
- Updated
- 2024/03/01
- Product number
- 13160
- Product name
- AT-56
- Purity
- ≥95%
- Packaging
- 5mg
- Price
- $90
- Updated
- 2024/03/01
- Product number
- 13160
- Product name
- AT-56
- Purity
- ≥95%
- Packaging
- 10mg
- Price
- $161
- Updated
- 2024/03/01
AT-56 Chemical Properties,Usage,Production
Uses
AT-56 is an orally active inhibitor of Lipocalin-type prostaglandin D synthase.
in vitro
AT-56 (1-30 μM; 10 minutes) dose-dependently inhibits the production of PGD2 in L-PGDS-expressing human medulloblastoma TE-671 cells with an IC50 of about 3 μM.
in vivo
AT-56 (1-30 mg/kg; p.o.) suppresses the PGD2 production in the stab-wounded brain.
AT-56 (1-10 mg/kg; p.o.) suppresses the L-PGDS-mediated allergic airway inflammation in mice.
AT-56 (10 mg/kg; p.o.) exhibits Cmax (2.15 μg/ml), half-life (1.71 h) and high oral bioavailability (82%).
storage
Store at -20°C
AT-56 Preparation Products And Raw materials
Raw materials
Preparation Products
AT-56 Suppliers
- Tel
- --
- Fax
- --
- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from AT-56 manufacturers
- Product
- 4-(5H-Dibenzo[a,d]cyclohepten-5-ylidene)-1-[4-(2H-tetrazol-5-yl)butyl]-piperidine 162640-98-4
- Price
- US $5.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- 1ton
- Release date
- 2019-09-03