ChemicalBook > CAS DataBase List > 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid

3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid

Product Name
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
CAS No.
196961-43-0
Chemical Name
3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
Synonyms
CD 3254;CD3254,CD-3254;CD3254, 10 mM in DMSO;3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid;2-Propenoic acid, 3-[4-hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-
CBNumber
CB72518841
Molecular Formula
C24H28O3
Formula Weight
364.48
MOL File
196961-43-0.mol
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3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Property

Melting point:
165 - 167°C
Boiling point:
508.0±50.0 °C(Predicted)
Density 
1.108±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.61±0.10(Predicted)
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
20870
Product name
CD3254
Purity
≥98%
Packaging
1mg
Price
$33
Updated
2024/03/01
Cayman Chemical
Product number
20870
Product name
CD3254
Purity
≥98%
Packaging
5mg
Price
$123
Updated
2024/03/01
Cayman Chemical
Product number
20870
Product name
CD3254
Purity
≥98%
Packaging
10mg
Price
$213
Updated
2024/03/01
Tocris
Product number
3302
Product name
CD3254
Purity
≥97%(HPLC)
Packaging
10
Price
$233
Updated
2021/12/16
Tocris
Product number
3302
Product name
CD3254
Purity
≥97%(HPLC)
Packaging
50
Price
$952
Updated
2021/12/16
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3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Chemical Properties,Usage,Production

Description

CD3254 is a selective agonist of the retinoid X receptors (RXRs; EC50 = ~10 nM for human RXRβ) that is without effect on retinoic acid receptors (RARs). It stimulates the recruitment of the nuclear receptor interaction domain of the TRAP220 coactivator to RXRα/RARβ heterodimers in vitro. CD3254 also enhances the recruitment of the PPARγ coactivator 1α, PGC-1α, to RXRα/PPARγ heterodimers.

Uses

CD 3254 is a potent RXR agonist.

storage

Store at -20°C

3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid Suppliers

China 29 United Kingdom 1 United States 8 Global 38
EMMX Biotechnology LLC
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TargetMol Chemicals Inc.
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196961-43-0, 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacidRelated Search:

Hydroxyurea L-Hydroxyproline CHLOROPHOSPHONAZO III

  • 3-[4-Hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-2-propenoicacid
  • CD 3254
  • 2-Propenoic acid, 3-[4-hydroxy-3-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)phenyl]-
  • CD3254,CD-3254
  • CD3254, 10 mM in DMSO
  • 196961-43-0