(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide

Product Name: (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
CAS No.: 330676-02-3
Chemical Name: (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
Synonyms: KH 7;sAC inhibitor KH7;inhibit,KH 7,Adenylate Cyclase,Adenylyl cyclase,KH7,Inhibitor,KH-7;2-((1H-Benzo[d]imidazol-2-yl)thio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide;(E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N′-(5-bromo-2-hydroxybenzylidene)propanehydrazide;(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide;Propanoic acid, 2-(1H-benzimidazol-2-ylthio)-, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide
CBNumber: CB72518881
Molecular Formula: C17H15BrN4O2S
Formula Weight: 419.3
MOL File: 330676-02-3.mol

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(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Property

Density: 1.61±0.1 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: >20mg/mL
form: powder
pka: 7.90±0.48(Predicted)
color: White to light yellow

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Safety

Hazard Codes: T
Risk Statements: 25
Safety Statements: 45
RIDADR: UN 2811 6.1 / PGIII

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word: Danger
Hazard statements: H301Toxic if swalloed
Precautionary statements: P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: K3394
Product name: KH7
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $112.4
Updated: 2024/03/01

Sigma-Aldrich

Product number: K3394
Product name: KH7
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $424
Updated: 2024/03/01

Cayman Chemical

Product number: 13243
Product name: KH7
Purity: ≥98%
Packaging: 5mg
Price: $81
Updated: 2024/03/01

Cayman Chemical

Product number: 13243
Product name: KH7
Purity: ≥98%
Packaging: 10mg
Price: $152
Updated: 2024/03/01

Cayman Chemical

Product number: 13243
Product name: KH7
Purity: ≥98%
Packaging: 25mg
Price: $356
Updated: 2024/03/01

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(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Chemical Properties,Usage,Production

Uses

KH7 has been used:

as a soluble adenyl?cyclase?(sAC) antagonist to study its effect on the signaling pathway mediated by the action of transient? receptor type 1 (TRPV1) in sperm cells.
as a selective sAC antagonist to study its effect on the signaling pathway of proton gated channels (HV1) induced action in sperm cells.
as a sAC inhibitor to study its effects on cAMP increase in monophosphorylated myosin light chain (pMLC).

Biochem/physiol Actions

KH7 is a selective inhibitor of soluble adenylyl cyclase. Soluble adenylyl cyclase (sAC) is an ubiquitously expressed, essential component of cAMP-signaling.

storage

Store at +4°C

(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Preparation Products And Raw materials

Raw materials

Preparation Products

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(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide Suppliers

China 58 United Kingdom 1 United States 9 Global 68

3B Pharmachem (Wuhan) International Co.,Ltd.

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BOC Sciences

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Sigma-Aldrich

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EMMX Biotechnology LLC

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Tianjin Kailiqi Biotechnology Co., Ltd.

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TargetMol Chemicals Inc.

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DC Chemicals

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View Lastest Price from (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide manufacturers

Career Henan Chemical Co

Product: (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide 330676-02-3
Price: US $0.01/KG
Min. Order: 500g
Purity: 98%; 99%
Supply Ability: 500g；1kg； 10kg; 25kg
Release date: 2020-01-08

330676-02-3, (±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazideRelated Search:

(±)-2-(1H-benzimidazol-2-ylthio)propanoicacid2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide

KH 7

(E)-2-(1H-Benzo[d]imidazol-2-ylthio)-N′-(5-bromo-2-hydroxybenzylidene)propanehydrazide

sAC inhibitor KH7

Propanoic acid, 2-(1H-benzimidazol-2-ylthio)-, 2-[(5-bromo-2-hydroxyphenyl)methylene]hydrazide

inhibit,KH 7,Adenylate Cyclase,Adenylyl cyclase,KH7,Inhibitor,KH-7

2-((1H-Benzo[d]imidazol-2-yl)thio)-N'-(5-bromo-2-hydroxybenzylidene)propanehydrazide

330676-02-3