3-bromo-2-methoxyaniline

Product Name: 3-bromo-2-methoxyaniline
CAS No.: 116557-46-1
Chemical Name: 3-bromo-2-methoxyaniline
Synonyms: 3-Bromo-o-anisidine;2-amino-6-bromoanisole;3-BROMO-2-METHOXYANILINE;3-Bromo-2- methoxylaniline;3-Bromo-2-methoxybenzenamine;3-Bromo-2-methoxy-phenylamine;BenzenaMine, 3-broMo-2-Methoxy-;3-bromo-2-methoxyphenylamine hydrochloride;2-Amino-6-bromoanisole, 3-Bromo-o-anisidine
CBNumber: CB72520161
Molecular Formula: C7H8BrNO
Formula Weight: 202.05
MOL File: 116557-46-1.mol

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3-bromo-2-methoxyaniline Property

Melting point:: 65℃
Boiling point:: 268℃
Density: 1.531
refractive index: 1.5430 to 1.5470
Flash point:: 116℃
storage temp.: Keep in dark place,Inert atmosphere,Room temperature
form: clear liquid
pka: 3.46±0.10(Predicted)
color: Light yellow to Brown
InChI: InChI=1S/C7H8BrNO/c1-10-7-5(8)3-2-4-6(7)9/h2-4H,9H2,1H3
InChIKey: ZLODWCIXZJMLJL-UHFFFAOYSA-N
SMILES: C1(N)=CC=CC(Br)=C1OC

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Safety

RIDADR: UN 2810 6.1/PG III
HazardClass: 6.1
PackingGroup: III
HS Code: 2922290090
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS023930
Product name: 3-Bromo-2-methoxyaniline
Packaging: 50mg
Price: $73.1
Updated: 2025/07/31

TCI Chemical

Product number: B5131
Product name: 3-Bromo-2-methoxyaniline
Purity: >98.0%(GC)(T)
Packaging: 1g
Price: $98
Updated: 2025/07/31

TCI Chemical

Product number: B5131
Product name: 3-Bromo-2-methoxyaniline
Purity: >98.0%(GC)(T)
Packaging: 5g
Price: $329
Updated: 2024/03/01

TRC

Product number: B700668
Product name: 3-Bromo-2-methoxyaniline
Packaging: 50mg
Price: $45
Updated: 2021/12/16

TRC

Product number: B700668
Product name: 3-Bromo-2-methoxyaniline
Packaging: 100mg
Price: $60
Updated: 2021/12/16

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3-bromo-2-methoxyaniline Chemical Properties,Usage,Production

Synthesis

98775-19-0

116557-46-1

The general procedure for the synthesis of 3-bromo-2-methoxyaniline from 2-bromo-6-nitroanisole was as follows: 1-bromo-2-methoxy-3-nitrobenzene (20.1 g, 86.6 mmol) was heated to 80 °C with iron powder (33.4 g, 598 mmol) in a solvent mixture of acetic acid/water (1:1, 600 mL). After the reaction lasted for 1.5 h, the mixture was cooled to room temperature and filtered. The filtered solid was washed several times with ethyl acetate and water. The organic layers were combined, washed with saturated aqueous NaHCO3, dried over anhydrous sodium sulfate and concentrated under reduced pressure. The residue was purified by column chromatography (eluent: petroleum ether/ethyl acetate = 20:1 to 10:1) to afford 3-bromo-2-methoxyaniline as a yellow solid (17.4 g, 99% yield).1H-NMR (300 MHz, DMSO-d6) δ (ppm): 3.66 (s, 3H), 5.23 (s, 2H), 6.64-6.76 (m, 1H). 3H).

References

[1] Patent: EP2987787, 2016, A1. Location in patent: Paragraph 0131
[2] Patent: WO2014/74661, 2014, A1. Location in patent: Paragraph 00173
[3] Patent: US2014/296229, 2014, A1. Location in patent: Paragraph 0258; 0259
[4] Patent: WO2014/154760, 2014, A1. Location in patent: Page/Page column 55-56
[5] Patent: WO2018/75937, 2018, A1. Location in patent: Paragraph 00487; 00495; 00496

3-bromo-2-methoxyaniline Preparation Products And Raw materials

Raw materials

Preparation Products

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3-bromo-2-methoxyaniline Suppliers

Americas 1 Belgium 1 Canada 1 China 107 Europe 1 Germany 4 India 11 Japan 3 Poland 1 United Kingdom 8 United States 31 Global 169

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View Lastest Price from 3-bromo-2-methoxyaniline manufacturers

Shaanxi Dideu Medichem Co. Ltd

Product: 3-bromo-2-methoxyaniline 116557-46-1
Price: US $1.00-4.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 200000KG
Release date: 2025-09-04

Shaanxi Dideu Medichem Co. Ltd

Product: 3-bromo-2-methoxyaniline 116557-46-1
Price: US $0.10-10.00/KG
Min. Order: 0.100000001490116KG
Purity: 98%
Supply Ability: 200TONS
Release date: 2025-09-02

Qingdao RENAS Polymer Material Co., Ltd.

Product: 3-bromo-2-methoxyaniline 116557-46-1
Price: US $0.00/kg
Min. Order: 10kg
Purity: 99%
Supply Ability: 10 tons
Release date: 2025-05-11

116557-46-1, 3-bromo-2-methoxyanilineRelated Search:

3-Bromo-2-methoxybenzenamine

2-Amino-6-bromoanisole, 3-Bromo-o-anisidine

2-amino-6-bromoanisole

BenzenaMine, 3-broMo-2-Methoxy-

3-Bromo-o-anisidine

3-bromo-2-methoxyphenylamine hydrochloride

3-Bromo-2-methoxy-phenylamine

3-BROMO-2-METHOXYANILINE

3-Bromo-2- methoxylaniline

116557-46-1