3'-OMe-2-NH2-A

Product Name: 3'-OMe-2-NH2-A
CAS No.: 80791-88-4
Chemical Name: 3'-OMe-2-NH2-A
Synonyms: 3'-OMe-2-NH2-A;2-Amino-3'-O-methyladenosine;3'-O-Methyl-2-AMino-adenosine;Adenosine, 2-aMino-3'-O-Methyl-;3'-O-Methyl-2,6-diaminopurine riboside;2-(2,6-diamino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol
CBNumber: CB72542732
Molecular Formula: C11H16N6O4
Formula Weight: 296.28
MOL File: 80791-88-4.mol

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3'-OMe-2-NH2-A Property

InChI: InChI=1S/C11H16N6O4/c1-20-7-4(2-18)21-10(6(7)19)17-3-14-5-8(12)15-11(13)16-9(5)17/h3-4,6-7,10,18-19H,2H2,1H3,(H4,12,13,15,16)/t4-,6-,7-,10-/m1/s1
InChIKey: DKDQFJWVNWYVPR-KQYNXXCUSA-N
SMILES: OC[C@H]1O[C@@H](N2C3C(=C(N=C(N)N=3)N)N=C2)[C@H](O)[C@@H]1OC

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Hazard and Precautionary Statements (GHS)

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3'-OMe-2-NH2-A Chemical Properties,Usage,Production

Uses

2-Amino-3’-O-methyladenosine is a purine nucleoside analog. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

References

[1] Man S, et al. Potential and promising anticancer drugs from adenosine and its analogs. Drug Discov Today. 2021 Jun;26(6):1490-1500. DOI:10.1016/j.drudis.2021.02.020
[2] Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88. DOI:10.2174/138161212801227005

3'-OMe-2-NH2-A Preparation Products And Raw materials

Raw materials

Preparation Products

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3'-OMe-2-NH2-A Suppliers

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80791-88-4, 3'-OMe-2-NH2-ARelated Search:

3'-OMe-2-NH2-A

3'-O-Methyl-2-AMino-adenosine

Adenosine, 2-aMino-3'-O-Methyl-

3'-O-Methyl-2,6-diaminopurine riboside

2-Amino-3'-O-methyladenosine

2-(2,6-diamino-9H-purin-9-yl)-5-(hydroxymethyl)-4-methoxytetrahydrofuran-3-ol

80791-88-4

Nucleosides-3'-OMe Nucleosides