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6-Fluoro-1H-pyrrolo[3,2-b]pyridine

Product Name
6-Fluoro-1H-pyrrolo[3,2-b]pyridine
CAS No.
1190320-33-2
Chemical Name
6-Fluoro-1H-pyrrolo[3,2-b]pyridine
Synonyms
6-Fluoro-4-azaindole;6-Fluoro-1H-pyrrolo[3,2-b]pyridine;1H-Pyrrolo[3,2-b]pyridine, 6-fluoro-
CBNumber
CB72550160
Molecular Formula
C7H5FN2
Formula Weight
136.13
MOL File
1190320-33-2.mol
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6-Fluoro-1H-pyrrolo[3,2-b]pyridine Property

Boiling point:
277.6±20.0 °C(Predicted)
Density 
1.370±0.06 g/cm3(Predicted)
storage temp. 
Inert atmosphere,Room Temperature
pka
14.06±0.40(Predicted)
Appearance
White to light brown Solid
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Safety

HS Code 
2933998090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P260Do not breathe dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

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N-Bromosuccinimide Price

TRC
Product number
F593143
Product name
6-Fluoro-1H-pyrrolo[3,2-b]pyridine
Packaging
10mg
Price
$45
Updated
2021/12/16
SynQuest Laboratories
Product number
3H31-3-5W
Product name
6-Fluoro-1H-pyrrolo[3,2-b]pyridine
Purity
97%
Packaging
250mg
Price
$280
Updated
2021/12/16
Apolloscientific
Product number
PC56323
Product name
6-Fluoro-1H-pyrrolo[3,2-b]pyridine
Purity
97%
Packaging
250mg
Price
$175
Updated
2021/12/16
AK Scientific
Product number
3237AA
Product name
6-Fluoro-1H-pyrrolo[3,2-b]pyridine
Packaging
100mg
Price
$184
Updated
2021/12/16
Apolloscientific
Product number
PC56323
Product name
6-Fluoro-1H-pyrrolo[3,2-b]pyridine
Purity
97%
Packaging
1g
Price
$425
Updated
2021/12/16
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6-Fluoro-1H-pyrrolo[3,2-b]pyridine Chemical Properties,Usage,Production

Synthesis

1445856-41-6

1190320-33-2

Step 3: To a solution of 5-fluoro-2-((trimethylsilyl)alkynyl)pyridin-3-amine (2.22 g, 10.7 mmol) in N,N-dimethylformamide (DMF, 30 mL) was added sodium hydride (60% Mineral Oil Dispersion, 1.025 g, 42.7 mmol) in one batch at 0 °C and under nitrogen protection. After addition, the reaction mixture was stirred at room temperature for 2 hours. Subsequently, the reaction solution was slowly poured into ice water and extracted with ethyl acetate (EtOAc). The organic phases were combined, dried over anhydrous magnesium sulfate (MgSO?), filtered and concentrated under reduced pressure to give 1.46 g of 6-fluoro-1H-pyrrolo[3,2-b]pyridine as a brown solid (100% yield). Mass spectrum (ESI): m/z = 137.2 [M + H]?

References

[1] Patent: WO2013/92940, 2013, A1. Location in patent: Page/Page column 51
[2] Patent: WO2016/103037, 2016, A1. Location in patent: Paragraph 00631

6-Fluoro-1H-pyrrolo[3,2-b]pyridine Preparation Products And Raw materials

Raw materials

Preparation Products

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6-Fluoro-1H-pyrrolo[3,2-b]pyridine Suppliers

A.J Chemicals
Tel
--
Fax
--
Email
sales@ajchem.in
Country
India
ProdList
6100
Advantage
58
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View Lastest Price from 6-Fluoro-1H-pyrrolo[3,2-b]pyridine manufacturers

Career Henan Chemical Co
Product
6-Fluoro-1H-pyrrolo[3,2-b]pyridine 1190320-33-2
Price
US $1.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
200kg
Release date
2020-01-09