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5-Morpholinopicolinic acid

Product Name
5-Morpholinopicolinic acid
CAS No.
1072103-29-7
Chemical Name
5-Morpholinopicolinic acid
Synonyms
5-Morpholinopicolinic acid;5-morpholin-4-ylpyridine-2-carboxylic acid;5-(4-Morpholinyl)-2-pyridinecarboxylic acid;2-Pyridinecarboxylic acid, 5-(4-morpholinyl)-
CBNumber
CB72552270
Molecular Formula
C10H12N2O3
Formula Weight
208.21
MOL File
1072103-29-7.mol
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5-Morpholinopicolinic acid Property

Boiling point:
446.1±45.0 °C(Predicted)
Density 
1.313±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
pka
0.86±0.50(Predicted)
Appearance
White to off-white Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

ChemScene
Product number
CS-0060454
Product name
5-Morpholinopicolinicacid
Purity
99.62%
Packaging
50mg
Price
$75
Updated
2021/12/16
ChemScene
Product number
CS-0060454
Product name
5-Morpholinopicolinicacid
Purity
99.62%
Packaging
100mg
Price
$97
Updated
2021/12/16
ChemScene
Product number
CS-0060454
Product name
5-Morpholinopicolinicacid
Purity
99.62%
Packaging
250mg
Price
$177
Updated
2021/12/16
ChemScene
Product number
CS-0060454
Product name
5-Morpholinopicolinicacid
Purity
99.62%
Packaging
1g
Price
$444
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0390965
Product name
5-MORPHOLINOPICOLINIC ACID
Purity
95.00%
Packaging
5MG
Price
$496.43
Updated
2021/12/16
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5-Morpholinopicolinic acid Chemical Properties,Usage,Production

Synthesis

1301214-68-5

1072103-29-7

4-[6-(piperidin-1-ylcarbonyl)pyridin-3-yl]morpholine (18.3 g) was added to 25% aqueous KOH solution (100 mL) and the mixture was heated to reflux. After the reaction was completed, the reaction solution was neutralized with HCl. Subsequently, the solution was concentrated under reduced pressure to remove the solvent. The product was purified by hot isopropanol extraction to give finally (5-morpholin-4-yl)pyridine-2-carboxylic acid (11.5 g, 71% yield). The product was detected by ESI MS and showed [M+H]+ peak of 209.7; 1H NMR (400 MHz, DMSO-d6) δ ppm: 8.34 (br.s, 1H), 8.03 (d, 1H), 7.65 (dd, 1H), 3.75 (br.s, 4H), 3.40 (br.s, 4H).

References

[1] Patent: US2011/111046, 2011, A1. Location in patent: Page/Page column 15
[2] Patent: WO2011/58473, 2011, A1. Location in patent: Page/Page column 30

5-Morpholinopicolinic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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1072103-29-7, 5-Morpholinopicolinic acidRelated Search:


  • 5-Morpholinopicolinic acid
  • 5-(4-Morpholinyl)-2-pyridinecarboxylic acid
  • 2-Pyridinecarboxylic acid, 5-(4-morpholinyl)-
  • 5-morpholin-4-ylpyridine-2-carboxylic acid
  • 1072103-29-7