Cyclopentanol, 3-amino-, hydrochloride (1:1)
- Product Name
- Cyclopentanol, 3-amino-, hydrochloride (1:1)
- CAS No.
- 1184919-69-4
- Chemical Name
- Cyclopentanol, 3-amino-, hydrochloride (1:1)
- Synonyms
- 3-aminocyclopentan-1-ol hydrochloride;3-AMinocyclopentanol, HCl;3-AMINO-CYCLOPENTANOL hyd...;3-AMinocyclopentanol hydr...;3-AMinocyclopentanol hdydrochloride;3-amino-Cyclopentanol hydrochloride (1:1);Cyclopentanol, 3-amino-, hydrochloride (1:1);3-Aminocyclopentanol hydrochloride (cis-trans mixture)
- CBNumber
- CB72552816
- Molecular Formula
- C5H12ClNO
- Formula Weight
- 137.61
- MOL File
- 1184919-69-4.mol
Cyclopentanol, 3-amino-, hydrochloride (1:1) Property
- storage temp.
- Inert atmosphere,Room Temperature
- Appearance
- Colorless to off-white Solid-Liquid Mixture
- InChI
- InChI=1S/C5H11NO.ClH/c6-4-1-2-5(7)3-4;/h4-5,7H,1-3,6H2;1H
- InChIKey
- SGKRJNWIEGYWGE-UHFFFAOYSA-N
- SMILES
- NC1CCC(O)C1.Cl
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- warning
- Hazard statements
-
H303May be harmfulif swallowed
H313May be harmful in contact with skin
H333May be harmful if inhaled
- Precautionary statements
-
P304+P312IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell.
P312Call a POISON CENTER or doctor/physician if you feel unwell.
N-Bromosuccinimide Price
- Product number
- A615888
- Product name
- 3-AminocyclopentanolHydrochloride
- Packaging
- 500mg
- Price
- $155
- Updated
- 2021/12/16
- Product number
- CS-W005211
- Product name
- 3-Aminocyclopentanolhydrochloride
- Packaging
- 250mg
- Price
- $55
- Updated
- 2021/12/16
- Product number
- CS-W005211
- Product name
- 3-Aminocyclopentanolhydrochloride
- Packaging
- 1g
- Price
- $131
- Updated
- 2021/12/16
- Product number
- CS-W005211
- Product name
- 3-Aminocyclopentanolhydrochloride
- Packaging
- 5g
- Price
- $385
- Updated
- 2021/12/16
- Product number
- 076323
- Product name
- 3-Aminocyclopentanol hydrochloride
- Purity
- 95+%
- Packaging
- 250mg
- Price
- $416
- Updated
- 2021/12/16
Cyclopentanol, 3-amino-, hydrochloride (1:1) Chemical Properties,Usage,Production
Uses
3-Aminocyclopentanol Hydrochloride is used in preparation of oxo-pyridine fusion ring derivatives as RON inhibitors for treatment of RON-related diseases.
Synthesis
1445796-28-0
1184919-69-4
General procedure for the synthesis of 3-aminocyclopentanol hydrochloride from the compound (CAS: 1445796-28-0): concentrated hydrochloric acid (HCl, 10 mL) was slowly added to a solution of compound 4 (8.0 g, 34 mmol) in methanol (MeOH, 100 mL), and the reaction mixture was subsequently heated and refluxed for 2 hours. Upon completion of the reaction, the mixture was concentrated under reduced pressure to remove the solvent. The obtained residue was dissolved in water and washed with ethyl acetate (EA). The aqueous phase was subsequently concentrated under reduced pressure to afford the target product 3-aminocyclopentanol hydrochloride (2.8 g, 82% yield) containing the HCl salt. The structure of the product was confirmed by 1H NMR (400 MHz, CDCl3) with the following chemical shifts (δ ppm): 4.33 (broad single peak, 1H), 3.66 (broad single peak, 1H), 2.08-2.16 (multiple peaks, 2H), 1.74-1.90 (multiple peaks, 4H).
References
[1] Patent: WO2013/96744, 2013, A1. Location in patent: Page/Page column 215
Cyclopentanol, 3-amino-, hydrochloride (1:1) Preparation Products And Raw materials
Raw materials
Preparation Products
Cyclopentanol, 3-amino-, hydrochloride (1:1) Suppliers
- Tel
- --
- Fax
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- sales@ajchem.in
- Country
- India
- ProdList
- 6100
- Advantage
- 58
View Lastest Price from Cyclopentanol, 3-amino-, hydrochloride (1:1) manufacturers
- Product
- 3-AMINO-CYCLOPENTANOL hyd... 1184919-69-4
- Price
- US $9.80/KG
- Min. Order
- 1KG
- Purity
- ≥98%
- Supply Ability
- 20 tons
- Release date
- 2020-01-10