Celastramycin A
- Product Name
- Celastramycin A
- CAS No.
- 491600-94-3
- Chemical Name
- Celastramycin A
- Synonyms
- Celastramycin A;Celastramycin A Exclusive;Methanone, (3-chloro-5-hexyl-2,6-dihydroxyphenyl)(4,5-dichloro-1H-pyrrol-3-yl)-
- CBNumber
- CB72560668
- Molecular Formula
- C17H18Cl3NO3
- Formula Weight
- 390.69
- MOL File
- 491600-94-3.mol
Celastramycin A Property
- storage temp.
- Store at -20°C
- solubility
- ≤20mg/ml in ethanol;20mg/ml in DMSO;20mg/ml in dimethyl formamide
- form
- crystalline solid
Safety
- HS Code
- 29419000
N-Bromosuccinimide Price
- Product number
- 13519
- Product name
- Celastramycin A
- Purity
- ≥97%
- Packaging
- 1mg
- Price
- $120
- Updated
- 2024/03/01
- Product number
- 13519
- Product name
- Celastramycin A
- Purity
- ≥97%
- Packaging
- 5mg
- Price
- $554
- Updated
- 2024/03/01
- Product number
- 13519
- Product name
- Celastramycin A
- Purity
- ≥97%
- Packaging
- 10mg
- Price
- $977
- Updated
- 2024/03/01
- Product number
- C249503
- Product name
- CelastramycinA
- Packaging
- 2.5mg
- Price
- $330
- Updated
- 2021/12/16
- Product number
- 1667AH
- Product name
- CelastramycinA
- Packaging
- 1mg
- Price
- $232
- Updated
- 2021/12/16
Celastramycin A Chemical Properties,Usage,Production
Uses
Celastramycin A is a bioactive compound isolated from endophytic bacteria.
Biological Activity
celastramycin a is an antibiotic that inhibits the growth of bacteria and mycobacteria and is also a potent innate immune suppressor [1][2].celastramycin a is a benzoyl pyrrole-type compound isolated from endophytic bacteria streptomyces mab-quh-8 living in plants of the celastraceae family. celastramycin a exhibited high activity against a series of multiresistent bacteria and mycobacteria [1]. celastramycin a inhibited the growth of gram-positive bacteria and mycobacteria with minimal inhibitory concentration (mic) as low as 0.05 μg/ml [1]. in the ex vivo drosophila culture system, celastramycin a showed a potent immunosuppressive effect with ic50 value of 0.008 μg/ml. in human umbilical vein endothelial cells (huvecs), celastramycin a potently inhibited the production of il-8 with ic50 value of 0.06 μg/ml. so celastramycin a could be used as a lead compound for novel immunosuppressive agents [2].
References
[1]. pullen c, schmitz p, meurer k, et al. new and bioactive compounds from streptomyces strains residing in the wood of celastraceae. planta. 2002 nov;216(1):162-7.
[2]. kikuchi h, sekiya m, katou y, et al. revised structure and synthesis of celastramycin a, a potent innate immune suppressor. org lett. 2009 apr 16;11(8):1693-5.
Celastramycin A Preparation Products And Raw materials
Raw materials
Preparation Products
Celastramycin A Suppliers
- Tel
- 18818260767
- Fax
- QQ 3610331285
- sales@chemegen.com
- Country
- China
- ProdList
- 11218
- Advantage
- 58
- Tel
- 021-69568360 18916172912
- order@med-bio.cn
- Country
- China
- ProdList
- 8140
- Advantage
- 58
- Tel
- 021-58432009 400-005-6266
- Fax
- 021-58436166
- marketing@energy-chemical.com
- Country
- China
- ProdList
- 44918
- Advantage
- 58
- Tel
- 021-65675885 18964387627
- customer_service@efebio.com
- Country
- China
- ProdList
- 11973
- Advantage
- 58
- Tel
- 13020159086
- yangjue@ygfuture.com
- Country
- China
- ProdList
- 424
- Advantage
- 58
- Tel
- 17701422019
- 1559451077@qq.com
- Country
- China
- ProdList
- 8167
- Advantage
- 58
- Tel
- 800-364-9897
- sales@caymanchem.com
- Country
- China
- ProdList
- 6838
- Advantage
- 58
- Tel
- 021-60936350
- scbt@scbt.com
- Country
- China
- ProdList
- 6594
- Advantage
- 58
- Tel
- +86-88938639 +86-17705817739
- info@dycnchem.com
- Country
- China
- ProdList
- 53899
- Advantage
- 58
- Tel
- 18566777408
- Country
- CHINA
- ProdList
- 156
- Advantage
- 58
- Tel
- 13251428727， 13368356747
- Country
- CHINA
- ProdList
- 157
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@neobioscience.com
- Country
- CHINA
- ProdList
- 6207
- Advantage
- 58
- Tel
- --
- Fax
- --
- chenjw@absin.cn
- Country
- CHINA
- ProdList
- 6208
- Advantage
- 58
- Tel
- --
- Fax
- --
- shxiyuanbio@163.com
- Country
- CHINA
- ProdList
- 6906
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@f-biology.com
- Country
- CHINA
- ProdList
- 6170
- Advantage
- 58
- Tel
- --
- Fax
- --
- sales@wheybio.com
- Country
- CHINA
- ProdList
- 4398
- Advantage
- 58
- Tel
- --
- Fax
- --
- lyn@biopike.com.cn
- Country
- CHINA
- ProdList
- 6646
- Advantage
- 58
- Tel
- --
- Fax
- --
- 471161314@qq.com
- Country
- CHINA
- ProdList
- 6210
- Advantage
- 58
- Tel
- --
- Fax
- --
- service@neobioscience.com
- Country
- CHINA
- ProdList
- 6151
- Advantage
- 58
- Tel
- --
- Fax
- --
- 2453006496@qq.com
- Country
- CHINA
- ProdList
- 6184
- Advantage
- 58
- Tel
- --
- Fax
- --
- 1914109725@qq.com
- Country
- CHINA
- ProdList
- 6518
- Advantage
- 58
- Tel
- --
- Fax
- --
- 978560024@qq.com
- Country
- CHINA
- ProdList
- 6458
- Advantage
- 58
- Tel
- --
- Fax
- --
- 470003480@QQ.COM
- Country
- CHINA
- ProdList
- 6955
- Advantage
- 58
- Tel
- --
- Fax
- --
- 1985563437@qq.com
- Country
- CHINA
- ProdList
- 6525
- Advantage
- 58
- Tel
- --
- Fax
- --
- john.st@163.com
- Country
- CHINA
- ProdList
- 2160
- Advantage
- 58
- Tel
- --
- Fax
- --
- 1861586486@qq.com
- Country
- CHINA
- ProdList
- 6648
- Advantage
- 58
- Tel
- --
- Fax
- --
- 912529879@qq.com
- Country
- CHINA
- ProdList
- 6448
- Advantage
- 58
- Tel
- --
- Fax
- --
- market@xlswkj.com
- Country
- CHINA
- ProdList
- 6793
- Advantage
- 58
- Tel
- --
- Fax
- --
- chenxue_gz@163.com
- Country
- CHINA
- ProdList
- 6600
- Advantage
- 58
- Tel
- --
- Fax
- --
- info@zzsrm.com
- Country
- CHINA
- ProdList
- 6650
- Advantage
- 58