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2-FLUOROPALMITIC ACID

Product Name
2-FLUOROPALMITIC ACID
CAS No.
16518-94-8
Chemical Name
2-FLUOROPALMITIC ACID
Synonyms
2-FLUOROPALMITIC ACID;2-FLUOROHEXADECANOIC ACID;JGRIJJOLCNCSNX-UHFFFAOYSA-N;Hexadecanoic acid, 2-fluoro-
CBNumber
CB7256741
Molecular Formula
C16H31FO2
Formula Weight
274.41
MOL File
16518-94-8.mol
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2-FLUOROPALMITIC ACID Property

Boiling point:
376.1±12.0 °C(Predicted)
Density 
0.936±0.06 g/cm3(Predicted)
storage temp. 
−20°C
solubility 
Soluble in DMSO
form 
crystalline solid
pka
2.70±0.21(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
90380
Product name
2-fluoro Palmitic Acid
Purity
≥98%
Packaging
5mg
Price
$61
Updated
2024/03/01
Cayman Chemical
Product number
90380
Product name
2-fluoro Palmitic Acid
Purity
≥98%
Packaging
10mg
Price
$115
Updated
2024/03/01
Cayman Chemical
Product number
90380
Product name
2-fluoro Palmitic Acid
Purity
≥98%
Packaging
25mg
Price
$272
Updated
2024/03/01
Cayman Chemical
Product number
90380
Product name
2-fluoro Palmitic Acid
Purity
≥98%
Packaging
50mg
Price
$513
Updated
2024/03/01
ApexBio Technology
Product number
C3924
Product name
2-fluoroPalmiticAcid
Packaging
50mg
Price
$432
Updated
2021/12/16
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2-FLUOROPALMITIC ACID Chemical Properties,Usage,Production

Definition

ChEBI: 2-fluorohexadecanoic acid is a long-chain fatty acid and a fluoro fatty acid.

Biological Activity

2-fluoropalmitic acid inhibits sphingosine biosynthesis and long-chain acyl-coa synthetase [1]. the length of the carbon chain of the fatty acid species defines the substrate specificity for the different acyl-coa synthetases (acs).mammalian long-chain acyl-coa synthetases (acsl) activate fatty acids with chain lengths of 12 to 20 carbon atoms. the long-chain acyl-coa synthetase mrna is expressed virtually in heart, liver, and epididymal adipose tissues and, to a much lesser extent, in brain, small intestine, and lung [2].palmitic acid was a selective cytotoxic substance extracted from the marine algal. at concentrations ranging from 12.5 to 50 μg/ml, palmitic acid showed selective cytotoxicity to human leukemic cells, but no cytotoxicity to normal hdf cells. palmitic acid (50 μg/ml) induced apoptosis in the human leukemic cell line molt-4. palmitic acid also showed in vivo antitumor activity in mice [3]. 2-fluoropalmitic acid showed an inhibitory effect on sphingosine biosynthesis and long-chain acyl-coa synthetase with an ic50 value of 0.2 mm [1].

References

[1] soltysiak r m, matsuura f, bloomer d, et al. d, l-α-fluoropalmitic acid inhibits sphingosine base formation and accumulates in membrane lipids of cultured mammalian cells[j]. biochimica et biophysica acta (bba)-lipids and lipid metabolism, 1984, 792(2): 214-226.
[2] suzuki h, kawarabayasi y, kondo j, et al. structure and regulation of rat long-chain acyl-coa synthetase[j]. journal of biological chemistry, 1990, 265(15): 8681-8685.
[3] harada h, yamashita u, kurihara h, et al. antitumor activity of palmitic acid found as a selective cytotoxic substance in a marine red alga[j]. anticancer research, 2001, 22(5): 2587-2590.

2-FLUOROPALMITIC ACID Preparation Products And Raw materials

Raw materials

Preparation Products

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2-FLUOROPALMITIC ACID Suppliers

Shanghai Boyle Chemical Co., Ltd.
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021-50182298 021-50180596
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sales@boylechem.com
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China
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BOC Sciences
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Shenzhen Regent Biochemical Technology Co., Ltd.
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ChemeGen(Shanghai) Biotechnology Co.,Ltd.
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Shanghai Universal Biotech Co.,Ltd
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13774214275
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gaojun@univ-bio.com
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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Shanghai Yifei Biotechnology Co. , Ltd.
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SHANGHAI ZZBIO CO., LTD.
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Alchem Pharmtech,Inc.
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TargetMol Chemicals Inc.
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+8613564774135
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zijue.cai@tsbiochem.com
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