ChemicalBook > CAS DataBase List > 3-aMino-5,6-dichloropyrazine-2-carboxylic acid

3-aMino-5,6-dichloropyrazine-2-carboxylic acid

Product Name
3-aMino-5,6-dichloropyrazine-2-carboxylic acid
CAS No.
4853-52-5
Chemical Name
3-aMino-5,6-dichloropyrazine-2-carboxylic acid
Synonyms
NSC 382681;2-Pyrazinecarboxylic acid, 3-aMino-5,6-dichloro-
CBNumber
CB72572968
Molecular Formula
C5H3Cl2N3O2
Formula Weight
208
MOL File
4853-52-5.mol
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3-aMino-5,6-dichloropyrazine-2-carboxylic acid Property

Melting point:
227 °C (decomp)
Boiling point:
424.5±45.0 °C(Predicted)
Density 
1.815±0.06 g/cm3(Predicted)
storage temp. 
Sealed in dry,Room Temperature
pka
3.05±0.10(Predicted)
Appearance
Light yellow to brown Solid
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P362Take off contaminated clothing and wash before reuse.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

AK Scientific
Product number
Z4788
Product name
3-Amino-5,6-dichloropyrazine-2-carboxylicacid
Packaging
100mg
Price
$70
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA46169
Product name
3-Amino-5,6-dichloropyrazine-2-carboxylic acid
Packaging
50mg
Price
$90
Updated
2021/12/16
Biosynth Carbosynth
Product number
FA46169
Product name
3-Amino-5,6-dichloropyrazine-2-carboxylic acid
Packaging
100mg
Price
$150
Updated
2021/12/16
AK Scientific
Product number
Z4788
Product name
3-Amino-5,6-dichloropyrazine-2-carboxylicacid
Packaging
5g
Price
$428
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
HCH0364332
Product name
3-AMINO-5,6-DICHLOROPYRAZINE-2-CARBOXYLIC ACID
Purity
95.00%
Packaging
5MG
Price
$499.88
Updated
2021/12/16
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3-aMino-5,6-dichloropyrazine-2-carboxylic acid Chemical Properties,Usage,Production

Synthesis

1458-18-0

4853-52-5

General procedure for the synthesis of 3-amino-5,6-dichloro-2-pyrazinecarboxylic acid from methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate: Referring to the preparation of Example 72 (Compound 207 in Table 1); a mixture of methyl 3-amino-5,6-dichloro-2-pyrazinecarboxylate (3.6 g, 16 mmol, Aldrich) and sodium hydroxide (1.6 g. 39 mmol) suspension in water (30 mL) was heated to reflux for 15 minutes. Upon completion of the reaction, the reaction mixture was filtered, cooled to room temperature and acidified with 1 N hydrochloric acid to pH < 7. The precipitated 3-amino-5,6-dichloro-pyrazine-2-carboxylic acid solid (1.2 g, 36% yield) was collected by filtration, dried in air and further dried under vacuum.

References

[1] Patent: WO2006/88920, 2006, A1. Location in patent: Page/Page column 147

3-aMino-5,6-dichloropyrazine-2-carboxylic acid Preparation Products And Raw materials

Raw materials

Preparation Products

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3-aMino-5,6-dichloropyrazine-2-carboxylic acid Suppliers

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4853-52-5, 3-aMino-5,6-dichloropyrazine-2-carboxylic acidRelated Search:


  • 2-Pyrazinecarboxylic acid, 3-aMino-5,6-dichloro-
  • NSC 382681
  • 4853-52-5
  • C5H3CI2N3O2