Avenanthramide-C methyl ester

Product Name: Avenanthramide-C methyl ester
CAS No.: 955382-52-2
Chemical Name: Avenanthramide-C methyl ester
Synonyms: IUZHCICFVDHVMC-XVNBXDOJSA-N;Avenanthramide-C methyl ester;Avenanthramide-C methyl ester Exclusive;Avenanthramide C methyl ester,AvenanthramideC methyl ester;methyl 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoate;Benzoic acid, 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-5-hydroxy-, methyl ester
CBNumber: CB72590319
Molecular Formula: C17H15NO6
Formula Weight: 329.3
MOL File: 955382-52-2.mol

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Avenanthramide-C methyl ester Property

storage temp.: Store at -20°C
solubility: DMF: 20 mg/ml; DMSO: 20 mg/ml; DMSO:PBS(pH7.2) (1:1): 0.5 mg/ml; Ethanol: 10 mg/ml
form: A crystalline solid

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical

Product number: 10011336
Product name: Avenanthramide-C methyl ester
Purity: ≥90%
Packaging: 500μg
Price: $55
Updated: 2024/03/01

Cayman Chemical

Product number: 10011336
Product name: Avenanthramide-C methyl ester
Purity: ≥90%
Packaging: 1mg
Price: $101
Updated: 2024/03/01

Cayman Chemical

Product number: 10011336
Product name: Avenanthramide-C methyl ester
Purity: ≥90%
Packaging: 5mg
Price: $420
Updated: 2024/03/01

Cayman Chemical

Product number: 10011336
Product name: Avenanthramide-C methyl ester
Purity: ≥90%
Packaging: 10mg
Price: $733
Updated: 2024/03/01

AK Scientific

Product number: 1632AH
Product name: Avenanthramide-Cmethylester
Packaging: 5mg
Price: $564
Updated: 2021/12/16

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Avenanthramide-C methyl ester Chemical Properties,Usage,Production

Description

Avenanthramide-C methyl ester is an inhibitor of NF-κB activation that acts by blocking the phosphorylation of IKK and IκB (IC₅₀ ~ 40 μM).¹ Through this mechanism, avenanthramide-C methyl ester dose dependently inhibits the expression and secretion of IL-6, IL-8, and MCP-1 in human aortic endothelial cells. ¹

Uses

Avenanthramide-C methyl ester is an anti-inflammatory agent and NF-κB inhibitor that inhibits the secretion of pro-inflammatory factors. Avenanthramide-C methyl ester inhibits NF-κB activation by inhibiting IKK and IκB phosphorylation and inhibiting proteasome activity[1].

References

1. Guo, W., Wise, M.L., Collins, F.W., et al. Avenanthramides, polyphenols from oats, inhibit IL-1β-induced NF-κB activation in endothelial cells Free Radic. Biol. Med. 44(3),415-429(2008).

Avenanthramide-C methyl ester Preparation Products And Raw materials

Raw materials

Preparation Products

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Avenanthramide-C methyl ester Suppliers

China 34 United States 4 Global 38

BOC Sciences

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955382-52-2, Avenanthramide-C methyl esterRelated Search:

Avenanthramide-C methyl ester

Avenanthramide-C methyl ester Exclusive

IUZHCICFVDHVMC-XVNBXDOJSA-N

methyl 2-[[(E)-3-(3,4-dihydroxyphenyl)prop-2-enoyl]amino]-5-hydroxybenzoate

Benzoic acid, 2-[[(2E)-3-(3,4-dihydroxyphenyl)-1-oxo-2-propen-1-yl]amino]-5-hydroxy-, methyl ester

Avenanthramide C methyl ester,AvenanthramideC methyl ester

955382-52-2