SEN 12333

Product Name: SEN 12333
CAS No.: 874450-44-9
Chemical Name: SEN 12333
Synonyms: SEN 12333;WAY 317538;SEN 12333 WAY-317538;SEN12333, 10 mM in DMSO;N-[4-(3-Pyridinyl)phenyl]-4-MorpholinepentanaMide;5-Morpholino-N-(4-(pyridin-3-yl)phenyl)pentanamide;4-MorpholinepentanaMide, N-[4-(3-pyridinyl)phenyl]-;SEN 12333, alpha7 nicotinic acetylcholine receptor (nAChR) agonist;Neuroprotective,nAChR,Inhibitor,SEN-12333,WAY317538,SEN12333,Alzheimer's Disease,inhibit,WAY 317538,Nicotinic acetylcholine receptors,schizophrenia,WAY-317538
CBNumber: CB72603004
Molecular Formula: C20H25N3O2
Formula Weight: 339.43
MOL File: 874450-44-9.mol

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SEN 12333 Property

storage temp.: Store at RT
solubility: Soluble to 100 mM in DMSO
form: Powder
color: White to light yellow

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris

Product number: 4441
Product name: SEN12333
Purity: ≥99%(HPLC)
Packaging: 10
Price: $130
Updated: 2021/12/16

Tocris

Product number: 4441
Product name: SEN12333
Purity: ≥99%(HPLC)
Packaging: 50
Price: $544
Updated: 2021/12/16

TRC

Product number: S258600
Product name: SEN12333
Packaging: 25mg
Price: $165
Updated: 2021/12/16

Usbiological

Product number: 256649
Product name: SEN 12333
Packaging: 10mg
Price: $446
Updated: 2021/12/16

Biosynth Carbosynth

Product number: BS171067
Product name: SEN 12333
Packaging: 100mg
Price: $450
Updated: 2021/12/16

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SEN 12333 Chemical Properties,Usage,Production

Uses

SEN 12333 is a nicotinic acetylcholine receptor (nAChR) agonist. SEN 12333 displays functional antagonism at histamine H3 receptors (IC50 = 103 nM) and weak agonist activity at human ganglionic α3 nAChRs (IC50 = 8.5 μM). Neuroprotective in a rodent model of quisqualic acid-induced cholinergic degeneration. SEN 12333 is a brain penetrant and orally bioavailable.

in vivo

SEN12333 (intraperitoneal injection; 3 mg/kg) improves episodic memory in a novel object recognition task in rats in conditions of spontaneous forgetting as well as cognitive disruptions induced via glutamatergic or cholinergic mechanisms. SEN12333 also prevents a scopolamine-induced deficit in a passive avoidance task^[1].

SEN 12333 Preparation Products And Raw materials

Raw materials

Preparation Products

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SEN 12333 Suppliers

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874450-44-9, SEN 12333Related Search:

SEN 12333

4-MorpholinepentanaMide, N-[4-(3-pyridinyl)phenyl]-

N-[4-(3-Pyridinyl)phenyl]-4-MorpholinepentanaMide

WAY 317538

SEN 12333 WAY-317538

5-Morpholino-N-(4-(pyridin-3-yl)phenyl)pentanamide

Neuroprotective,nAChR,Inhibitor,SEN-12333,WAY317538,SEN12333,Alzheimer's Disease,inhibit,WAY 317538,Nicotinic acetylcholine receptors,schizophrenia,WAY-317538

SEN 12333, alpha7 nicotinic acetylcholine receptor (nAChR) agonist

SEN12333, 10 mM in DMSO

874450-44-9

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Heterocycles

Intermediates & Fine Chemicals

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