ChemicalBook > CAS DataBase List > 2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-

2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-

Product Name
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-
CAS No.
865305-30-2
Chemical Name
2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-
Synonyms
Ro 4;AF 353;CS-2469;CHEMBL526307;AF-353 (Ro-4);AF-353, 10 mM in DMSO;CHEMBL526307;AF 353;AF353;5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine;Ro4,inhibit,AF-353,P2X Receptor,Inhibitor,Ro 4,P2XRs,AF353,AF 353;5-[5-Iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine
CBNumber
CB72609596
Molecular Formula
C14H17IN4O2
Formula Weight
400.21
MOL File
865305-30-2.mol
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2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Property

Boiling point:
510.2±60.0 °C(Predicted)
Density 
1.619±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 32 mg/mL (79.96 mM)
form 
Solid
pka
6.89±0.10(Predicted)
color 
Light brown to brown
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23034
Product name
AF-353
Packaging
1mg
Price
$32
Updated
2022/04/27
Cayman Chemical
Product number
23034
Product name
AF-353
Packaging
5mg
Price
$102
Updated
2022/04/27
Cayman Chemical
Product number
23034
Product name
AF-353
Packaging
10mg
Price
$189
Updated
2022/04/27
AK Scientific
Product number
1897CW
Product name
2,4-Pyrimidinediamine,5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-
Packaging
10mg
Price
$245
Updated
2021/12/16
ChemScene
Product number
CS-5061
Product name
AF-353
Purity
98.95%
Packaging
25mg
Price
$310
Updated
2021/12/16
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2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Chemical Properties,Usage,Production

Description

AF-353 is a noncompetitive dual antagonist of the purinoreceptors P2X3 and P2X2/3 (IC50s = 10 and 79.4 nM, respectively). It is selective for P2X3 and P2X2/3 over P2X1, P2X2, P2X4, P2X5, and P2X7 (IC50 = >10 μM for all). It inhibits calcium flux in CHO-K1 cells expressing the rat P2X3 receptor and in 1321N1 cells expressing the human P2X3 and P2X2/3 receptors (IC50s = 8.91, 8.71, and 38.9 nM, respectively). AF-353 decreases the electrical signals in the detrusor, but not striated, muscle of the bladder in female rats.

2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Preparation Products And Raw materials

Raw materials

Preparation Products

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2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- Suppliers

China 64 United Kingdom 1 United States 9 Global 74
MedChemexpress LLC
Tel
021-58955995
Fax
609-228-5909
Email
sales@medchemexpress.cn
Country
United States
ProdList
4861
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58
Target molecule Corp.
Tel
857-239-0968
Fax
857-239-8801
Email
service1@targetmol.com
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United States
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Musechem
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+1-800-259-7612
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+1-800-259-7612
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info@musechem.com
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United States
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4660
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TargetMol Chemicals Inc.
Tel
+1-781-999-5354 +1-00000000000
Email
marketing@targetmol.com
Country
United States
ProdList
32161
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InvivoChem
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+1-708-310-1919 +1-13798911105
Fax
708-557-7486
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sales@invivochem.cn
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United States
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Cckinase, Inc.
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+1 (732)236-3202
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sales@cckinase.com
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United States
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BOC Sciences
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+1-631-485-4226
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1-631-614-7828
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inquiry@bocsci.com
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United States
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Aladdin Scientific
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+1-+1(833)-552-7181
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sales@aladdinsci.com
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United States
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Cayman Chemical Company
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cayman@caymanchem.com
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United States
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6213
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81
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View Lastest Price from 2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]- manufacturers

Hong Kong Tiansheng New Material Trading Co., Ltd
Product
af-353 865305-30-2
Price
US $100.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
100KG
Release date
2021-09-13
Hong Kong Tiansheng New Material Trading Co., Ltd
Product
af-353 865305-30-2
Price
US $100.00/Kg/Bag
Min. Order
1KG
Purity
99%
Supply Ability
10kg
Release date
2021-09-15

865305-30-2, 2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-Related Search:


  • 2,4-PyriMidinediaMine, 5-[5-iodo-4-Methoxy-2-(1-Methylethyl)phenoxy]-
  • AF 353
  • Ro 4
  • 5-{[5-iodo-2-(1-Methylethyl)-4-(Methyloxy)phenyl]oxy}-2,4-pyriMidinediaMine
  • CHEMBL526307
  • CHEMBL526307;AF 353;AF353
  • CS-2469
  • 5-[5-iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine hydrochloride Ro 4 hydrochloride
  • 5-[5-Iodo-4-methoxy-2-(1-methylethyl)phenoxy]-2,4-pyrimidinediamine
  • AF-353 (Ro-4)
  • 5-(5-iodo-4-methoxy-2-propan-2-ylphenoxy)pyrimidine-2,4-diamine
  • Ro4,inhibit,AF-353,P2X Receptor,Inhibitor,Ro 4,P2XRs,AF353,AF 353
  • AF-353, 10 mM in DMSO
  • 865305-30-2
  • C14H17IN4O2
  • Inhibitors