7-hydroxy-N,N,2-triMethyl-3-tosyl-3H-benzo[d]iMidazole-5-carboxaMide Property

Boiling point:

654.0±65.0 °C(Predicted)

Density 

1.36±0.1 g/cm3(Predicted)

pka

7.07±0.40(Predicted)

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Danger

Hazard statements

H226Flammable liquid and vapour

H304May be fatal if swallowed and enters airways

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P233Keep container tightly closed.

P240Ground/bond container and receiving equipment.

P241Use explosion-proof electrical/ventilating/lighting/…/equipment.

P242Use only non-sparking tools.

P243Take precautionary measures against static discharge.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P310IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

P303+P361+P353IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.

P331Do NOT induce vomiting.

P370+P378In case of fire: Use … for extinction.

P403+P235Store in a well-ventilated place. Keep cool.

P405Store locked up.

7-hydroxy-N,N,2-triMethyl-3-tosyl-3H-benzo[d]iMidazole-5-carboxaMide Chemical Properties,Usage,Production

Uses

7-hydroxy-N,N,2-triMethyl-3-tosyl-3H-benzo[d]iMidazole-5-carboxaMide is mainly used in organic synthesis or pharmaceutical backbone materials. It can be used in the synthesis of benzimidazole derivatives as selective acid pump inhibitors for the treatment of conditions with antagonistic activity mediated by the acid pump, such as gastrointestinal disorders, gastro-oesophageal disorders, gastro-oesophageal reflux disease (GERD), laryngo-pharyngeal reflux disease, peptic ulcers, gastric ulcers, duodenal ulcers, and others.