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ALPHA-ENDORPHIN

Product Name
ALPHA-ENDORPHIN
CAS No.
59004-96-5
Chemical Name
ALPHA-ENDORPHIN
Synonyms
LPH(61-76);a-Endorphin;α-Endorphin;ALPHA-ENDORPHIN;YGGFMTSEKSQTPLVT;ENDORPHIN, ALPHA-;A-ENDORPHIN HUMAN;α-endorphin human;α-Endorphin human;β-Lipotropin 61-76
CBNumber
CB7261017
Molecular Formula
C77H120N18O26S
Formula Weight
1745.95
MOL File
59004-96-5.mol
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ALPHA-ENDORPHIN Property

RTECS 
JZ2270000
storage temp. 
−20°C
solubility 
≥174.5 mg/mL in DMSO; insoluble in EtOH; ≥52.7 mg/mL in H2O
form 
White powder
Stability:
Hygroscopic
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
10
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Alfa Aesar
Product number
J63462
Product name
alpha-Endorphin, human
Packaging
1mg
Price
$120
Updated
2023/06/20
Cayman Chemical
Product number
24958
Product name
α-Endorphin (human, mouse, rat, porcine, bovine, ovine)
Purity
≥95%
Packaging
1mg
Price
$87
Updated
2024/03/01
TRC
Product number
E555588
Product name
α-Endorphin
Packaging
10mg
Price
$290
Updated
2021/12/16
Usbiological
Product number
E2300-40D
Product name
a-Endorphin
Packaging
1mg
Price
$531
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0000463
Product name
ALPHA-ENDORPHIN
Purity
95.00%
Packaging
1MG
Price
$557
Updated
2021/12/16
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ALPHA-ENDORPHIN Chemical Properties,Usage,Production

Uses

An opioid peptide and substrate for transglutaminase

Biological Activity

endorphins are endogenous opioid peptides that function as neurotransmitters(1). they are produced by the pituitary gland and the hypothalamus in vertebrates during exercise, excitement, pain, consumption of spicy food, love and orgasm, and they resemble the opiates in their abilities to produce analgesia and a feeling of well-being.the term implies a pharmacological activity (analogous to the activity of the corticosteroid category of biochemicals) as opposed to a specific chemical formulation. it consists of two parts: endo- and -orphin; these are short forms of the words endogenous and morphine(2), beta-endorphin (β-endorphin) is released into blood from the pituitary gland and into the spinal cord and brain from hypothalamic neurons. the β-endorphin that is released into the blood cannot enter the brain in large quantities because of the blood–brain barrier, so the physiological importance of the β-endorphin that can be measured in the blood is far from clear. β-endorphin is a cleavage product of pro-opiomelanocortin (pomc), which is also the precursor hormone for adrenocorticotrophic hormone (acth). the behavioural effects of β-endorphin are exerted by its actions in the brain and spinal cord, and it is presumed that the hypothalamic neurons are the major source of β-endorphin at these sites. in situations where the level of acth is increased (e.g., cushing’s syndrome), the level of endorphins also increases slightly(3).figure1 formula of a-endorphinfigure 2 mechanism of endorphin to inhibit lhrh release

References

1. Oswald Steward: Functional neuroscience (2000), page 116.2. Goldstein A, Lowery PJ (September 1975). "Effect of the opiate antagonist naloxone on body temperature in rats". Life Sciences 17 (6): 927–31.3. Simantov R, Snyder S (1976). "Morphine-like peptides in mammalian brain: isolation, structure elucidation, and interactions with the opiate receptor". Proc Natl Acad Sci USA 73 (7): 2515–9.

ALPHA-ENDORPHIN Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from ALPHA-ENDORPHIN manufacturers

Hebei Binshare New Material Co. Ltd
Product
ALPHA-ENDORPHIN 59004-96-5
Price
US $60.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
10mt
Release date
2022-10-19
Career Henan Chemical Co
Product
ALPHA-ENDORPHIN 59004-96-5
Price
US $7.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
100kg
Release date
2020-02-18

59004-96-5, ALPHA-ENDORPHINRelated Search:


  • α-Endorphin human, ≥97% (HPLC)
  • TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-LEU-PHE-LYS-ASN-ALA-ILE-ILE-LYS-ASN-ALA-TYR-LYS-LYS-GLY-GLU
  • LPH(61-76)
  • synthetic, β-Lipotropin 61-76
  • β-Lipotropin(61-76), human
  • b-Endorphin (1-16), b-Lipotropin (59-74) (huMan)
  • alpha-Endorphin (pig)
  • alpha-Endorphin (porcine)
  • alpha-Endorphin (sheep)
  • Porcine alpha-endorphin
  • β-Lipotropin 61-76
  • β-Endorphin (1-16)
  • -Endorphin (human, mouse, rat, porcine, bovine, ovine)
  • BETA-ENDORPHIN (1-16)
  • BETA-LIPOTROPIN (59-74) (HUMAN)
  • BETA-LIPOTROPIN (61-76)
  • ENDORPHIN, ALPHA-
  • H-TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR-OH
  • ALPHA-ENDORPHIN
  • ALPHA-ENDORPHIN HUMAN
  • YGGFMTSEKSQTPLVT
  • TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR
  • TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-TYR
  • ALPHA-ENDORPHIN HUMAN SYNTHETIC
  • A-ENDORPHIN HUMAN
  • α-endorphin human
  • β-lipotropin (61-76), human, synthetic
  • a-Endorphin
  • TYR-GLY-GLY-PHE-MET-THR-SER-GLU-LYS-SER-GLN-THR-PRO-LEU-VAL-THR: YGGFMTSEKSQTPLVT
  • β-Lipotropin (61-76), human, synthetic, β-Lipotropin 61-76, LPH (61-76), Tyr-Gly-Gly-Phe-Met-Thr-Ser-Glu-Lys-Ser-Gln-Thr-Pro-Leu-Val-Thr
  • α-Endorphin
  • ALPHA-ENDORPHIN USP/EP/BP
  • β-Endorphin (1-16)
  • alpha-Endorphin acetate
  • alpha-Endorphin acetate (59004-96-5 Free base)
  • α-Endorphin human
  • alpha Endorphin acetate,alphaEndorphin acetate
  • 59004-96-5/61214-51-5
  • α-Endorphin (human, mouse, rat, porcine, bovine, ovine)
  • 59004-96-5
  • C158H251N39O46S1
  • C77H120N18O26S
  • Mass Spectrometry
  • Peptide and protein standards for mass spectrometry analysis
  • Proteomics and Protein Expression
  • Protein Analysis
  • BioChemical
  • Neuroscience
  • Peptide