Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester
- Product Name
- Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester
- CAS No.
- 775304-60-4
- Chemical Name
- Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester
- Synonyms
- Ataluren impurity C;Ataluren Impurity 6;Ataluren impurities6;Thiocoraline Impurity12;Methyl 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]benzoate;3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-Benzoic acid Methyl ester;Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester
- CBNumber
- CB72610187
- Molecular Formula
- C16H11FN2O3
- Formula Weight
- 298.27
- MOL File
- 775304-60-4.mol
Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester Property
- Boiling point:
- 457.2±55.0 °C(Predicted)
- Density
- 1.289±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- pka
- -3.63±0.50(Predicted)
- Appearance
- White to off-white Solid
N-Bromosuccinimide Price
- Product number
- A126935
- Product name
- Methyl3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
- Purity
- 97%
- Packaging
- 250mg
- Price
- $19
- Updated
- 2021/12/16
- Product number
- A126935
- Product name
- Methyl3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
- Purity
- 97%
- Packaging
- 1g
- Price
- $41
- Updated
- 2021/12/16
- Product number
- A126935
- Product name
- Methyl3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
- Purity
- 97%
- Packaging
- 5g
- Price
- $141
- Updated
- 2021/12/16
- Product number
- 775304604
- Product name
- Methyl3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
- Packaging
- 1g
- Price
- $202
- Updated
- 2021/12/16
- Product number
- CM255019
- Product name
- Methyl3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate
- Purity
- 95+%
- Packaging
- 1g
- Price
- $204
- Updated
- 2021/12/16
Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester Chemical Properties,Usage,Production
Synthesis
1141475-82-2
393-52-2
775304-60-4
GENERAL METHOD: 2 mmol of methyl (E)-3-(N'-hydroxycarbamoyl)benzoate was dissolved in 200 mL of acetone in a round-bottomed flask; subsequently, 0.35 g (2.5 mmol) of K2CO3 and 2.5 mmol of o-fluorobenzoyl chloride were added to the reaction mixture, and the reaction was stirred for 24 h at room temperature. Upon completion of the reaction, the solvent was removed by distillation under reduced pressure and the residue was treated with an appropriate amount of water and refluxed for 30 minutes. After the reaction mixture was cooled, the 1,2,4-oxadiazole product was collected by filtration and further purified by column chromatography to afford the target compound, methyl 3-(5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl)benzoate.
References
[1] European Journal of Medicinal Chemistry, 2015, vol. 101, p. 236 - 244
[2] Bioorganic and Medicinal Chemistry Letters, 2014, vol. 24, # 11, p. 2473 - 2476
Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester Preparation Products And Raw materials
Raw materials
Preparation Products
Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester Suppliers
- Tel
- 44-20819178-90 02081917890
- Fax
- (0)2080432064
- info@novachemistry.com
- Country
- United Kingdom
- ProdList
- 4381
- Advantage
- 58
View Lastest Price from Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester manufacturers
- Product
- Ataluren Impurity 775304-60-4
- Price
- US $0.00-0.00/mg
- Min. Order
- 10mg
- Purity
- 99%+ HPLC
- Supply Ability
- 1000
- Release date
- 2025-05-22
- Product
- Benzoic acid, 3-[5-(2-fluorophenyl)-1,2,4-oxadiazol-3-yl]-, Methyl ester 775304-60-4
- Price
- US $1.80/KG
- Min. Order
- 1g
- Purity
- 96%-99%
- Supply Ability
- 1kg/10kg/100kg
- Release date
- 2020-11-11