ChemicalBook > CAS DataBase List > MBX2982

MBX2982

Product Name
MBX2982
CAS No.
1037792-44-1
Chemical Name
MBX2982
Synonyms
CS-485;MBX2982;SAR-260093;MBX-2982, >=98%;MBX2982 / MBX-2982;MBX-2982 (SAR260093);MBX-2982;MBX 2982;MBX2982;2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole;4-((4-(1H-Tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole;pyrimidine, 5-ethyl-2-[4-[4-[[4-(1h-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-
CBNumber
CB72620009
Molecular Formula
C22H24N8OS
Formula Weight
448.54
MOL File
1037792-44-1.mol
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MBX2982 Property

Boiling point:
683.6±65.0 °C(Predicted)
Density 
1.42
storage temp. 
Store at -20°C
solubility 
DMSO : 50 mg/mL (111.47 mM; Need ultrasonic)H2O : < 0.1 mg/mL (insoluble)
form 
Powder
pka
5.39±0.42(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P321Specific treatment (see … on this label).

P330Rinse mouth.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

P403+P233Store in a well-ventilated place. Keep container tightly closed.

P405Store locked up.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Cayman Chemical
Product number
22206
Product name
MBX-2982
Purity
≥98%
Packaging
5mg
Price
$153
Updated
2024/03/01
Cayman Chemical
Product number
22206
Product name
MBX-2982
Purity
≥98%
Packaging
10mg
Price
$275
Updated
2024/03/01
Cayman Chemical
Product number
22206
Product name
MBX-2982
Purity
≥98%
Packaging
25mg
Price
$606
Updated
2024/03/01
Cayman Chemical
Product number
22206
Product name
MBX-2982
Purity
≥98%
Packaging
50mg
Price
$844
Updated
2024/03/01
ChemScene
Product number
CS-0745
Product name
MBX-2982
Purity
99.54%
Packaging
5mg
Price
$196
Updated
2021/12/16
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MBX2982 Chemical Properties,Usage,Production

Description

MBX-2982 is an agonist of GPR119. It reduces nuclear and total protein levels of sterol regulatory element binding protein 1 (SREBP-1) in HepG2 cells and rat primary hepatocytes under high-glucose and -insulin conditions and increases phosphorylation of the inhibitory form, SREBP-1c. MBX-2982 (10 mg/kg) inhibits hepatic lipid accumulation in wild-type, but not GPR119 knockout, mice fed a high-fat diet. It also increases plasma levels of glucagon-like peptide 1 (GLP-1; ) in mice when administered at a dose of 10 mg/kg prior to, and to a greater extent following, glucose administration. MBX-2982 increases glucokinase activity in an enzyme assay with an EC50 value of 45.11 μM.

MBX2982 Preparation Products And Raw materials

Raw materials

Preparation Products

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MBX2982 Suppliers

China 77 India 1 The Netherlands 1 United States 11 Global 90
Shanghai Boyle Chemical Co., Ltd.
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View Lastest Price from MBX2982 manufacturers

Career Henan Chemical Co
Product
MBX2982 1037792-44-1
Price
US $1.00/g
Min. Order
1g
Purity
99%
Supply Ability
20kg
Release date
2019-12-23

1037792-44-1, MBX2982Related Search:


  • MBX2982
  • 5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine
  • MBX2982 / MBX-2982
  • 5-Ethyl-2-[4-[4-[[[4-(1H-tetrazol-1-yl)phenyl]oxy]methyl]thiazol-2-yl]piperidin-1-yl]pyrimidine MBX-2982
  • pyrimidine, 5-ethyl-2-[4-[4-[[4-(1h-tetrazol-1-yl)phenoxy]methyl]-2-thiazolyl]-1-piperidinyl]-
  • 2-[1-(5-ethylpyrimidin-2-yl)-4-piperidyl]-4-[[4-(tetrazol-1-yl)phenoxy]methyl]thiazole
  • MBX-2982, >=98%
  • SAR-260093
  • MBX-2982;MBX 2982;MBX2982
  • CS-485
  • MBX-2982 (SAR260093)
  • 4-((4-(1H-Tetrazol-1-yl)phenoxy)methyl)-2-(1-(5-ethylpyrimidin-2-yl)piperidin-4-yl)thiazole
  • 1037792-44-1
  • Inhibitors