Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-

Product Name: Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-
CAS No.: 1246213-24-0
Chemical Name: Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-
Synonyms: Ivacaftor Impurity 1;Ivacaftor impurities5;Ivacaftor carboxylate;Ivacaftor Carboxylic Acid;Ivacaftor Carboxylic Acid Impurity;2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid;2-(5-tert-butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid;Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-;Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-alpha,alpha-diMethyl-
CBNumber: CB72624683
Molecular Formula: C24H26N2O5
Formula Weight: 422.48
MOL File: 1246213-24-0.mol

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Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Property

Melting point:: >213°C (dec.)
Boiling point:: 624.1±55.0 °C(Predicted)
Density: 1.299±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO (Slightly), Methanol (Slightly)
form: Solid
pka: 4.33±0.16(Predicted)
color: White to Light Yellow

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P280Wear protective gloves/protective clothing/eye protection/face protection.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

TRC

Product number: I940605
Product name: IvacaftorCarboxylicAcid
Packaging: 10mg
Price: $1390
Updated: 2021/12/16

TRC

Product number: I940605
Product name: IvacaftorCarboxylicAcid
Packaging: 25mg
Price: $3345
Updated: 2021/12/16

TRC

Product number: I940605
Product name: IvacaftorCarboxylicAcid
Packaging: 1mg
Price: $180
Updated: 2021/12/16

Usbiological

Product number: 452811
Product name: Ivacaftor Carboxylic Acid
Packaging: 2.5mg
Price: $368
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: CHM0387892
Product name: 2-(5-(TERT-BUTYL)-2-HYDROXY-4-(4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDO)PHENYL)-2-METHYLPROPANOIC ACID
Purity: 95.00%
Packaging: 5MG
Price: $495.53
Updated: 2021/12/16

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Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Chemical Properties,Usage,Production

Uses

Ivacaftor Carboxylic Acid is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Suppliers

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1246213-24-0, Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-Related Search:

Ivacaftor Carboxylic Acid

2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid

Ivacaftor Impurity 1

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-alpha,alpha-diMethyl-

2-(5-tert-butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid

Ivacaftor Carboxylic Acid Impurity

Ivacaftor carboxylate

Ivacaftor impurities5

1246213-24-0