ChemicalBook > CAS DataBase List > Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-

Product Name
Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-
CAS No.
1246213-24-0
Chemical Name
Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-
Synonyms
Ivacaftor Impurity 1;Ivacaftor impurities5;Ivacaftor carboxylate;Ivacaftor Carboxylic Acid;Ivacaftor Carboxylic Acid Impurity;2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid;2-(5-tert-butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid;Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-;Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-;Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-alpha,alpha-diMethyl-
CBNumber
CB72624683
Molecular Formula
C24H26N2O5
Formula Weight
422.48
MOL File
1246213-24-0.mol
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Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Property

Melting point:
>213°C (dec.)
Boiling point:
624.1±55.0 °C(Predicted)
Density 
1.299±0.06 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
DMSO (Slightly), Methanol (Slightly)
form 
Solid
pka
4.33±0.16(Predicted)
color 
White to Light Yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
I940605
Product name
IvacaftorCarboxylicAcid
Packaging
10mg
Price
$1390
Updated
2021/12/16
TRC
Product number
I940605
Product name
IvacaftorCarboxylicAcid
Packaging
25mg
Price
$3345
Updated
2021/12/16
TRC
Product number
I940605
Product name
IvacaftorCarboxylicAcid
Packaging
1mg
Price
$180
Updated
2021/12/16
Usbiological
Product number
452811
Product name
Ivacaftor Carboxylic Acid
Packaging
2.5mg
Price
$368
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
CHM0387892
Product name
2-(5-(TERT-BUTYL)-2-HYDROXY-4-(4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDO)PHENYL)-2-METHYLPROPANOIC ACID
Purity
95.00%
Packaging
5MG
Price
$495.53
Updated
2021/12/16
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Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Chemical Properties,Usage,Production

Uses

Ivacaftor Carboxylic Acid is an impurity of Ivacaftor (I940600); a drug used in the treatment of cystic fibrosis.

Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Preparation Products And Raw materials

Raw materials

Preparation Products

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Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl- Suppliers

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1246213-24-0, Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-Related Search:


  • Ivacaftor Carboxylic Acid
  • 2-[5-tert-butyl-2-hydroxy-4-[(4-oxo-1H-quinoline-3-carbonyl)amino]phenyl]-2-methylpropanoic acid
  • Ivacaftor Impurity 1
  • Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-
  • Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-alpha,alpha-diMethyl-
  • 2-(5-tert-butyl-2-hydroxy-4-(4-oxo-1,4-dihydroquinoline-3-carboxamido)phenyl)-2-methylpropanoic acid
  • Ivacaftor Carboxylic Acid Impurity
  • Ivacaftor carboxylate
  • Benzeneacetic acid, 4-[[(1,4-dihydro-4-oxo-3-quinolinyl)carbonyl]aMino]-5-(1,1-diMethylethyl)-2-hydroxy-α,α-diMethyl-
  • Ivacaftor impurities5
  • 1246213-24-0