ChemicalBook > CAS DataBase List > MK-2206
MK-2206
- Product Name
- MK-2206
- CAS No.
- 1032349-93-1
- Chemical Name
- MK-2206
- Synonyms
- MK-2206(FREE BASE);Benodanil Impurity 8;8-(4-(1-aminocyclobutyl)phenyl)-9-phenyl-[1,2,4]triazolo[3,4-f][1,6]naphthyridin-3-ol;1,2,4-Triazolo[3,4-f][1,6]naphthyridin-3(2H)-one, 8-[4-(1-aminocyclobutyl)phenyl]-9-phenyl-
- CBNumber
- CB72628146
- Molecular Formula
- C25H21N5O
- Formula Weight
- 407.47
- MOL File
- 1032349-93-1.mol
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N-Bromosuccinimide Price
American Custom Chemicals Corporation
- Product number
- API0006847
- Product name
- MK-2206
- Purity
- 95.00%
- Packaging
- 10MG
- Price
- $360.15
- Updated
- 2021/12/16
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MK-2206 Chemical Properties,Usage,Production
Uses
A highly selective inhibitor of Akt. Akt1, IC50=8 nM; Akt2, IC50=12 nM; Akt3, IC50=65 nM.
Definition
ChEBI: MK-2206 is an organic heterotricyclic compound that is [1,2,4]triazolo[3,4-f][1,6]naphthyridin-3(2H)-one substituted at positions 8 and 9 respectively by 4-(1-aminocyclobutyl)phenyl and phenyl groups. It has a role as an EC 2.7.1.137 (phosphatidylinositol 3-kinase) inhibitor. It is functionally related to a 1,6-naphthyridine.
IC 50
Akt1: 8 nM (IC50); Akt2: 12 nM (IC50); Akt3: 65 nM (IC50)
MK-2206 Preparation Products And Raw materials
Raw materials
Preparation Products
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