IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate

Product Name: IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate
CAS No.: 38092-95-4
Chemical Name: IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate
Synonyms: desmethylazatadine;Dechloro desloratadine;Deschloro Desloratadine;Desloratadine IMpurity A;Desloratadine Impurity R;Desloratadine impurity E;Desloratadine Impurity 14;Fludesloratadine impurity E;Desloratadine EP Impurity A (N-;Desloratadine Impurity A (N-Desmethyl Azatadine)
CBNumber: CB72630224
Molecular Formula: C19H20N2
Formula Weight: 276.38
MOL File: 38092-95-4.mol

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IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate Property

Boiling point:: 443.2±45.0 °C(Predicted)
Density: 1.139±0.06 g/cm3(Predicted)
solubility: Chloroform (Slightly), Ethyl Acetate (Slightly)
pka: 10.30±0.20(Predicted)
form: Solid
color: White to Off-White

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: D290940
Product name: N-DesmethylAzatadine
Packaging: 2.5mg
Price: $105
Updated: 2021/12/16

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IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate Chemical Properties,Usage,Production

Uses

N-Desmethyl Azatadine is a minor metabolite of Azatadine Dimaleate (A802950); an antihistamine.

IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate Suppliers

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38092-95-4, IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylateRelated Search:

Desloratadine N-Carboxylic Acid Methyl Ester Desloratadine-d7 (Major) Desloratadine Citric Amide 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-d 1-Oxide Desloratadine Epoxide DESLORATADINE-D4 Desloratadine D5 Desloratadine Pyridine N-oxide Desloratadine IMpurity 3 8-Dechloro-9-chloro Desloratadine 5,6-Dehydro-N-methyl Desloratadine Desloratadine IMpurity 1 Desloratadine 8-Deschloro-8-bromo-N-methyl Desloratadine 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Iso Desloratadine Desloratadine IMpurity B Desloratadine N-Hydroxypiperidine

IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate

Desloratadine IMpurity A

11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

Desloratadine Impurity R

Desloratadine Impurity A (N-Desmethyl Azatadine)

Desloratadine Impurity 14

desmethylazatadine

6,11-Dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 6,11-dihydro-11-(4-piperidinylidene)-

Desloratadine impurity E

Fludesloratadine impurity E

Deschloro Desloratadine

Loratadine impurity A (Desloratadine Deschloro Impurity/ N-Desmethyl Azatadine)

Desloratadine Deschloro Impurity (Loratadine impurity A/ N-Desmethyl Azatadine)

Desloratadine EP Impurity A (N-

Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate

Dechloro desloratadine

12-(Piperidin-4-ylidene)-5,6,7,12-tetrahydrobenzo[6,7]cycloocta[1,2-b]pyridine

38092-95-4