ChemicalBook > CAS DataBase List > IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate

IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate

Product Name
IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate
CAS No.
38092-95-4
Chemical Name
IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate
Synonyms
desmethylazatadine;Dechloro desloratadine;Deschloro Desloratadine;Desloratadine IMpurity A;Desloratadine Impurity R;Desloratadine impurity E;Desloratadine Impurity 14;Fludesloratadine impurity E;Desloratadine EP Impurity A (N-;Desloratadine Impurity A (N-Desmethyl Azatadine)
CBNumber
CB72630224
Molecular Formula
C19H20N2
Formula Weight
276.38
MOL File
38092-95-4.mol
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IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate Property

Boiling point:
443.2±45.0 °C(Predicted)
Density 
1.139±0.06 g/cm3(Predicted)
solubility 
Chloroform (Slightly), Ethyl Acetate (Slightly)
pka
10.30±0.20(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D290940
Product name
N-DesmethylAzatadine
Packaging
2.5mg
Price
$105
Updated
2021/12/16
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IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate Chemical Properties,Usage,Production

Uses

N-Desmethyl Azatadine is a minor metabolite of Azatadine Dimaleate (A802950); an antihistamine.

IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate Preparation Products And Raw materials

Raw materials

Preparation Products

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IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate Suppliers

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38092-95-4, IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylateRelated Search:

Desloratadine N-Carboxylic Acid Methyl Ester Desloratadine-d7 (Major) Desloratadine Citric Amide 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine-d 1-Oxide Desloratadine Epoxide DESLORATADINE-D4 Desloratadine D5 Desloratadine Pyridine N-oxide Desloratadine IMpurity 3 8-Dechloro-9-chloro Desloratadine 5,6-Dehydro-N-methyl Desloratadine Desloratadine IMpurity 1 Desloratadine 8-Deschloro-8-bromo-N-methyl Desloratadine 8-Chloro-11-fluoro-6,11-dihydro-11-(4-piperidinyl)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine Iso Desloratadine Desloratadine IMpurity B Desloratadine N-Hydroxypiperidine

  • IMp. A (EP): Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate
  • Desloratadine IMpurity A
  • 11-piperidin-4-ylidene-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • Desloratadine Impurity R
  • Desloratadine Impurity A (N-Desmethyl Azatadine)
  • Desloratadine Impurity 14
  • desmethylazatadine
  • 6,11-Dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine
  • 5H-Benzo[5,6]cyclohepta[1,2-b]pyridine, 6,11-dihydro-11-(4-piperidinylidene)-
  • Desloratadine impurity E
  • Fludesloratadine impurity E
  • Deschloro Desloratadine
  • Loratadine impurity A (Desloratadine Deschloro Impurity/ N-Desmethyl Azatadine)
  • Desloratadine Deschloro Impurity (Loratadine impurity A/ N-Desmethyl Azatadine)
  • Desloratadine EP Impurity A (N-
  • Ethyl 4-[(11RS)-8-Chloro-11-hydroxy-6,11-dihydro-5H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-yl]piperidine-1-carboxylate
  • Dechloro desloratadine
  • 12-(Piperidin-4-ylidene)-5,6,7,12-tetrahydrobenzo[6,7]cycloocta[1,2-b]pyridine
  • 38092-95-4