2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine

Product Name: 2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine
CAS No.: 1375301-91-9
Chemical Name: 2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine
Synonyms: 2-Cyclopropylpyrimidin-5-ylboronic acid pinacol ester;2-(Cyclopropyl)pyrimidine-5-boronic acid pinacol ester;2-cyclopropyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine;2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine;Pyrimidine, 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-;2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine - [C31856]
CBNumber: CB72637733
Molecular Formula: C13H19BN2O2
Formula Weight: 246.11
MOL File: 1375301-91-9.mol

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2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine Property

Boiling point:: 355.5±15.0 °C(Predicted)
Density: 1.11±0.1 g/cm3(Predicted)
storage temp.: under inert gas (nitrogen or Argon) at 2-8°C
form: solid
pka: 1.83±0.22(Predicted)
Appearance: Off-white to light brown Solid

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: CDS021186
Product name: 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Packaging: 10 mg
Price: $73.1
Updated: 2025/07/31

TRC

Product number: C991645
Product name: 2-(Cyclopropyl)pyrimidine-5-boronicacidpinacolester
Packaging: 100mg
Price: $65
Updated: 2021/12/16

Synthonix

Product number: C31856
Product name: 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Purity: 90+%
Packaging: 1g
Price: $410
Updated: 2021/12/16

Synthonix

Product number: C31856
Product name: 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Purity: 90+%
Packaging: 5g
Price: $1300
Updated: 2021/12/16

AK Scientific

Product number: 9065BB
Product name: 2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine
Packaging: 5g
Price: $1369
Updated: 2021/12/16

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2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine Chemical Properties,Usage,Production

Synthesis

304902-96-3

73183-34-3

1375301-91-9

5-Bromo-2-cyclopropylpyrimidine (12A, 0.8 g, 4.02 mmol) and pinacol ester of bisboronic acid (1.16 g, 4.82 mmol) were reacted in the presence of Pd(dppf)Cl2 (147 mg, 0.20 mmol) and KOAc (592 mg, 6.03 mmol) in dioxane (20 mL). The reaction mixture was heated to 90 °C and kept at this temperature overnight. After completion of the reaction, the mixture was cooled and subsequently concentrated. Purification of the residue by silica gel column chromatography (eluent ratio from 1/50 to 1/10 ethyl acetate/petroleum ether) afforded the target product 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine (12B, 0.38 g, 39% yield) as a yellow solid.ESI m/z 247.1 [M + H].

References

[1] Patent: US2018/291002, 2018, A1. Location in patent: Paragraph 0427; 0429

2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine Preparation Products And Raw materials

Raw materials

Preparation Products

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2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine Suppliers

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View Lastest Price from 2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine manufacturers

Hebei Chuanghai Biotechnology Co., Ltd

Product: 2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine 1375301-91-9
Price: US $10.00/KG
Min. Order: 1KG
Purity: 99%
Supply Ability: 10 mt
Release date: 2024-11-19

1375301-91-9, 2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidineRelated Search:

2-cyclopropyl-5-(4,4,5,5-tetraMethyl-1,3,2-dioxaborolan-2-yl)pyriMidine

2-Cyclopropylpyrimidin-5-ylboronic acid pinacol ester

2-(Cyclopropyl)pyrimidine-5-boronic acid pinacol ester

2-cyclopropyl-5-(tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine

Pyrimidine, 2-cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-

2-Cyclopropyl-5-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)pyrimidine - [C31856]

1375301-91-9