ChemicalBook > CAS DataBase List > BVT-14225

BVT-14225

Product Name
BVT-14225
CAS No.
376638-65-2
Chemical Name
BVT-14225
Synonyms
BVT-14225;BVT-14225, >98%;BVT14225;BVT 14225;BVT-14225, 10 mM in DMSO;inhibit,Inhibitor,BVT-14225,BVT14225;2-(2-(3-Chloro-2-methylphenylsulfonamido)thiazol-4-yl)-n,n-diethylacetamide;4-Thiazoleacetamide,2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-N,N-diethyl-;2-[2-(3-chloro-2-methylbenzenesulfonamido)-1,3-thiazol-4-yl]-N,N-diethylacetamide
CBNumber
CB72662984
Molecular Formula
C16H20ClN3O3S2
Formula Weight
401.93
MOL File
376638-65-2.mol
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BVT-14225 Property

Boiling point:
586.5±60.0 °C(Predicted)
Density 
1.373±0.06 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO : ≥ 27 mg/mL (67.18 mM)
pka
6.34±0.10(Predicted)
form 
Solid
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Chemenu
Product number
CM321672
Product name
2-(2-(3-Chloro-2-methylphenylsulfonamido)thiazol-4-yl)-N,N-diethylacetamide
Purity
95%
Packaging
1g
Price
$884
Updated
2021/12/16
Crysdot
Product number
CD11133137
Product name
2-(2-(3-Chloro-2-methylphenylsulfonamido)thiazol-4-yl)-N,N-diethylacetamide
Purity
95+%
Packaging
1g
Price
$937
Updated
2021/12/16
DC Chemicals
Product number
DC8278
Product name
BVT-14225
Purity
>98%
Packaging
1g
Price
$1900
Updated
2021/12/16
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BVT-14225 Chemical Properties,Usage,Production

Uses

BVT-14225 is a selective 11β-Hydroxysteroid dehydrogenase type 1 (11β-HSD1) inhibitor with an IC50 of 52 nM.

References

[1] Barf T, et al. Arylsulfonamidothiazoles as a new class of potential antidiabetic drugs. Discovery of potent and selective inhibitors of the 11beta-hydroxysteroid dehydrogenase type 1. J Med Chem. 2002 Aug 29;45(18):3813-5. DOI:10.1021/jm025530f
[2] Vicker N, et al. Novel non-steroidal inhibitors of human 11beta-hydroxysteroid dehydrogenase type 1. J Steroid Biochem Mol Biol. 2007 May;104(3-5):123-9. DOI:10.1016/j.jsbmb.2007.03.023

BVT-14225 Preparation Products And Raw materials

Raw materials

Preparation Products

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BVT-14225 Suppliers

Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
Nanjing Chemlin Chemical Co., Ltd
Tel
025-83697070 13770331960
Fax
+86-25-83453306
Email
info@chemlin.com.cn
Country
China
ProdList
16059
Advantage
64
BOC Sciences
Tel
1-631-485-4226; 16314854226
Email
info@bocsci.com
Country
United States
ProdList
12952
Advantage
65
Shanghai JiYi Biotechnology Co. Ltd.
Tel
13621943973
Fax
-
Email
sales@shjiyipharmatech.com
Country
China
ProdList
1166
Advantage
55
Shanghai Lollane Biological Technology Co.,Ltd.
Tel
021-52996696,15000506266 15000506266
Fax
+86-21-52996696
Country
China
ProdList
4827
Advantage
55
Shanghai EFE Biological Technology Co., Ltd.
Tel
021-65675885 18964387627
Fax
021-65675885
Email
info@efebio.com
Country
China
ProdList
9803
Advantage
58
Shanghai YuanYe Biotechnology Co., Ltd.
Tel
021-61312847; 18021002903
Fax
QQ:3008007432
Email
3008007409@qq.com
Country
China
ProdList
89689
Advantage
60
Tianjin Kailiqi Biotechnology Co., Ltd.
Tel
15076683720
Fax
022-23754520
Email
klq@cw-bio.com
Country
China
ProdList
9697
Advantage
55
Shanghai Chaolan Chemical Technology Center
Tel
021-QQ:65489617 15618227136
Fax
21-5161 9052
Email
Sales@ATKchemical.com
Country
China
ProdList
9550
Advantage
58
Amadis Chemical Company Limited
Tel
571-89925085
Fax
0086-571-89925065
Email
sales@amadischem.com
Country
China
ProdList
131957
Advantage
58

376638-65-2, BVT-14225Related Search:


  • BVT-14225
  • 4-Thiazoleacetamide,2-[[(3-chloro-2-methylphenyl)sulfonyl]amino]-N,N-diethyl-
  • BVT14225;BVT 14225
  • BVT-14225, >98%
  • 2-(2-(3-Chloro-2-methylphenylsulfonamido)thiazol-4-yl)-n,n-diethylacetamide
  • inhibit,Inhibitor,BVT-14225,BVT14225
  • 2-[2-(3-chloro-2-methylbenzenesulfonamido)-1,3-thiazol-4-yl]-N,N-diethylacetamide
  • BVT-14225, 10 mM in DMSO
  • 376638-65-2