(1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid
- Product Name
- (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid
- CAS No.
- 1351413-50-7
- Chemical Name
- (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid
- Synonyms
- (1-methyl-2-oxopyridin-4-yl)boronic acid;(1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid;B-(1,2-Dihydro-1-methyl-2-oxo-4-pyridinyl)boronic acid;Boronic acid, B-(1,2-dihydro-1-methyl-2-oxo-4-pyridinyl)-;(1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid(contains varying amounts of Anhydride)
- CBNumber
- CB72663350
- Molecular Formula
- C6H8BNO3
- Formula Weight
- 152.94
- MOL File
- 1351413-50-7.mol
(1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid Property
- Boiling point:
- 356.2±52.0 °C(Predicted)
- Density
- 1.30±0.1 g/cm3(Predicted)
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- pka
- 8.26±0.20(Predicted)
- Appearance
- White to yellow Solid
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- M266335
- Product name
- 1-Methyl-2-oxo-1,2-dihydro-4-pyridinylboronicAcid
- Packaging
- 50mg
- Price
- $95
- Updated
- 2021/12/16
- Product number
- CS-W005874
- Product name
- (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronicacid
- Purity
- >97.0%
- Packaging
- 250mg
- Price
- $76
- Updated
- 2021/12/16
- Product number
- CS-W005874
- Product name
- (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronicacid
- Purity
- >97.0%
- Packaging
- 1g
- Price
- $208
- Updated
- 2021/12/16
- Product number
- 2218AQ
- Product name
- (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronicacid
- Packaging
- 1g
- Price
- $585.2
- Updated
- 2021/12/16
- Product number
- CS-W005874
- Product name
- (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronicacid
- Purity
- >97.0%
- Packaging
- 5g
- Price
- $710
- Updated
- 2021/12/16
(1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid Chemical Properties,Usage,Production
Uses
1-Methyl-2-oxo-1,2-dihydro-4-pyridinylboronic Acid is an intermediate used to prepare thiazolopyridine ureas as antitubercular agents acting through inhibition of DNA gyrase B.
Synthesis
1160790-84-0
1351413-50-7
(3) The residue from step (2) was dissolved in 1,4-dioxane (500-1000 mL), concentrated hydrochloric acid (500-1000 mL) was added slowly at 25°C and the reaction was stirred for 12 hours. Upon completion of the reaction, the organic phase was separated by extraction using ethyl acetate. The aqueous phase product was concentrated under reduced pressure to remove the solvent to give a white solid product (53.3 g, 60% yield).
References
[1] Patent: CN106986885, 2017, A. Location in patent: Paragraph 0015; 0016; 0017
(1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid Preparation Products And Raw materials
Raw materials
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View Lastest Price from (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronic acid manufacturers
- Product
- (1-Methyl-2-oxo-1,2-dihydropyridin-4-yl)boronicacid 1351413-50-7
- Price
- US $1.00/KG
- Min. Order
- 1KG
- Purity
- 99%
- Supply Ability
- KG/T
- Release date
- 2019-12-17