ChemicalBook > CAS DataBase List > 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine

5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine

Product Name
5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine
CAS No.
1246535-95-4
Chemical Name
5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine
Synonyms
VS-5584 analog;Desmethyl-VS-5584;DESMETHYL VS 5584; DESMETHYL VS5584;5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine;5-[2-(morpholin-4-yl)-9-(propan-2-yl)-9H-purin-6-yl]pyrimidin-2-amine;5-[9-(1-Methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine;2-Pyrimidinamine, 5-[9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-;Desmethyl-SB2343,Dual inhibitor,Selectivity,DesmethylVS5584,Mammalian target of Rapamycin,PI3K,Phosphoinositide 3-kinase,mTOR,Inhibitor,Desmethyl VS 5584,inhibit
CBNumber
CB72666407
Molecular Formula
C16H20N8O
Formula Weight
340.38
MOL File
1246535-95-4.mol
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5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Property

Boiling point:
669.3±65.0 °C(Predicted)
Density 
1.52±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
Chloroform: 0.5mg/mL
form 
A solid
pka
3.94±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
30324
Product name
VS-5584 analog
Packaging
1mg
Price
$44
Updated
2024/03/01
Cayman Chemical
Product number
30324
Product name
VS-5584 analog
Packaging
25mg
Price
$692
Updated
2024/03/01
Cayman Chemical
Product number
30324
Product name
VS-5584 analog
Packaging
5mg
Price
$193
Updated
2024/03/01
Cayman Chemical
Product number
30324
Product name
VS-5584 analog
Packaging
10mg
Price
$341
Updated
2024/03/01
AK Scientific
Product number
1189DU
Product name
5-(9-Isopropyl-2-morpholino-9H-purin-6-yl)pyrimidin-2-amine
Packaging
5mg
Price
$313
Updated
2021/12/16
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5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Chemical Properties,Usage,Production

Description

VS-5584 analog is a dual inhibitor of PI3Kα and mammalian target of rapamycin (mTOR; IC50s = 17 and 150 nM, respectively). It is a desmethyl analog of the dual PI3K/mTOR inhibitor VS-5584 .

Uses

An intermediate in the preparation of purine compounds as therapeutic kinase inhibitors.

5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Preparation Products And Raw materials

Raw materials

Preparation Products

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5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine Suppliers

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1246535-95-4, 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMineRelated Search:

URMC-099 CC-223 N-[4-[(2-Methoxyethyl)methylamino]phenyl]-2-phenyl-5-(trifluoromethyl)-4-oxazolecarboxamide (S)-3-(aMinoMethyl)-7-(3-hydroxypropoxy)benzo[c][1,2]oxaborol-1(3H)-ol

  • Desmethyl-VS-5584
  • 5-(9-isopropyl-2-Morpholino-9H-purin-6-yl)pyriMidin-2-aMine
  • 5-[9-(1-Methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-2-pyrimidinamine
  • 5-[2-(morpholin-4-yl)-9-(propan-2-yl)-9H-purin-6-yl]pyrimidin-2-amine
  • DESMETHYL VS 5584; DESMETHYL VS5584
  • 2-Pyrimidinamine, 5-[9-(1-methylethyl)-2-(4-morpholinyl)-9H-purin-6-yl]-
  • VS-5584 analog
  • Desmethyl-SB2343,Dual inhibitor,Selectivity,DesmethylVS5584,Mammalian target of Rapamycin,PI3K,Phosphoinositide 3-kinase,mTOR,Inhibitor,Desmethyl VS 5584,inhibit
  • 1246535-95-4