ChemicalBook > CAS DataBase List > bisBenziMide H 33342 trihydrochloride
bisBenziMide H 33342 trihydrochloride
- Product Name
- bisBenziMide H 33342 trihydrochloride
- CAS No.
- 875756-97-1
- Chemical Name
- bisBenziMide H 33342 trihydrochloride
- Synonyms
- CS-1351;98% (HPLC and TLC);Hoechst-33342, HOE 33342;HOE 33342 trihydrochloride;Hoechst 33342 (hydrochloride);Hoechst 33342 (trihydrochloride);Hoechst 33342 trihydrochloride, >99%;2'-(4-Ethoxyphenyl)-5-(4-methylpiperazin-1-yl)-1H,1'H-2,5'-bibenzo[d]imidazole trihydrochloride;Autophagy,bisBenzimide H 33342 trihydrochloride,Hoechst 33342 trihydrochloride,inhibit,HOE 33342 trihydrochloride,Inhibitor;BISBENZIMIDE H 33342 TRIHYDROCHLORIDE;HOE 33342 TRIHYDROCHLORIDE;HOECHST-33342 TRIHYDROCHLORIDE;HOECHST33342 TRIHYDROCHLORIDE
- CBNumber
- CB72667565
- Molecular Formula
- C27H29ClN6O
- Formula Weight
- 489.02
- MOL File
- 875756-97-1.mol
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bisBenziMide H 33342 trihydrochloride Property
- storage temp.
- Inert atmosphere,Store in freezer, under -20°C
- solubility
- Soluble in water, N,N-dimethylformamide, methano
- pka
- 11.08 ± 0.69, most acidic, temperature: 25 °C; 7.66 ± 0.42, most basic(at 25℃)
- form
- A crystalline solid
- color
- Yellow to green powder or solid
- PH
- 1.7 (20°C)
- Appearance
- Solid Powder
- Water Solubility
- H2O: 20mg/mL
phosphate buffer: precipitates - λmax
- 350 nm (H2O/DNA); 357 nm (MeOH/H+)
- Biological Applications
- Detecting β-amyloid (Aβ) plaques; detecting/measuring microorganisms; identifying/counting cells; studying multidrug resistance; apoptosis assay; cell cycle assay; cell proliferation assay; measuring membrane potential; treating disc degenerative disease, erectile dysfunction
- Major Application
- Photoresists
- InChIKey
- OTMWRDPOAAYNCR-UHFFFAOYSA-N
- SMILES
- CN1CCN(C2=CC=C3N=C(C4=CC=C5N=C(C6C=CC(OCC)=CC=6)NC5=C4)NC3=C2)CC1.Cl
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Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
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N-Bromosuccinimide Price
Sigma-Aldrich
- Product number
- B2261
- Product name
- bisBenzimide H 33342 trihydrochloride
- Purity
- ≥98% (HPLC and TLC)
- Packaging
- 25MG
- Price
- $48.67
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- B2261
- Product name
- bisBenzimide H 33342 trihydrochloride
- Purity
- ≥98%(HPLCandTLC)
- Packaging
- 100mg
- Price
- $160
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- B2261
- Product name
- bisBenzimide H 33342 trihydrochloride
- Purity
- ≥98% (HPLC and TLC)
- Packaging
- 500MG
- Price
- $559
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- B2261
- Product name
- bisBenzimide H 33342 trihydrochloride
- Purity
- ≥98%(HPLCandTLC)
- Packaging
- 1g
- Price
- $888
- Updated
- 2025/07/31
Sigma-Aldrich
- Product number
- 14533
- Product name
- bisBenzimide H 33342 trihydrochloride
- Purity
- for fluorescence, ≥97.0% (HPLC)
- Packaging
- 100MG
- Price
- $197
- Updated
- 2025/07/31
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bisBenziMide H 33342 trihydrochloride Chemical Properties,Usage,Production
Description
Hoechst 33342 is a cell-permeable DNA dye that binds to the minor groove of adenine and thymine-rich sequences. It emits blue fluorescence (excitation 350 nm/emission maximum 461 nm) when bound to double stranded DNA.
Uses
Bisbenzimide Hoechst 33342 is a specific stain for AT-rich regions of double-stranded DNA and has been shown to displace several known DNA intercalators. This fluorescent dye has been used in sorting living cells based on DNA content, used in flow cytometry for the determination of DNA content, and for the visualization of chromatin distribution in living cells. It has been used to detect BrdU incorporation into cells and in studying the initial stages apoptosis and cellcycle distribution., Chromosomes th at are dividing or replicating will not stain with this dye. ', 'Useful for staining DNA, chromosomes and nuclei. May be used for fluorescence microscopy or flow cytometry.
Excitation max. = 346 nm
Emission max. = 460 nm
Biological Activity
Membrane-permeable, fluorescent DNA stains with low cytotoxicity th at intercalate in A-T regions of DNA.
storage
-20°C
Excitation / Emission Maximum
350 nm/461 nm
bisBenziMide H 33342 trihydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
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bisBenziMide H 33342 trihydrochloride Suppliers
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