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H2L 5765834

Product Name
H2L 5765834
CAS No.
420841-84-5
Chemical Name
H2L 5765834
Synonyms
H2L 5765834;H2L 5765834, 10 mM in DMSO;HFYPTENHTPNXGP-UHFFFAOYSA-N;2-(3-(4-Nitrophenoxy)phenyl)-1,3-dioxoisoindoline-5-carboxylic acid;2,3-Dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid;1H-Isoindole-5-carboxylic acid, 2,3-dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-;LPL Receptor,lysophosphatidic,inhibit,Lysophospholipid Receptor,Inhibitor,LPA,receptors,acid,H2L 5765834,H-2L 5765834
CBNumber
CB72667868
Molecular Formula
C21H12N2O7
Formula Weight
404.33
MOL File
420841-84-5.mol
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H2L 5765834 Property

Boiling point:
665.8±65.0 °C(Predicted)
Density 
1.544±0.06 g/cm3(Predicted)
storage temp. 
Store at 4°C
solubility 
<40.43mg/ml in DMSO
pka
3.31±0.20(Predicted)
form 
Solid
color 
Light yellow to yellow
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Tocris
Product number
4870
Product name
H2L5765834
Purity
≥99%(HPLC)
Packaging
10
Price
$219
Updated
2021/12/16
Tocris
Product number
4870
Product name
H2L5765834
Purity
≥99%(HPLC)
Packaging
50
Price
$860
Updated
2021/12/16
TRC
Product number
H456355
Product name
H2L5765834
Packaging
1mg
Price
$110
Updated
2021/12/16
Usbiological
Product number
255430
Product name
H2L 5765834
Packaging
10mg
Price
$466
Updated
2021/12/16
ApexBio Technology
Product number
B5744
Product name
H2L5765834
Packaging
10mg
Price
$322
Updated
2021/12/16
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H2L 5765834 Chemical Properties,Usage,Production

Uses

H2L 5765834 (cas# 420841-84-5) is a novel LPA3 antagonist which may be used in treatment of systemic sclerosis.

in vivo

H2L 5765834 (20 mg/kg; i.p.) could not affect the LPA-induced decrease of alanine transaminase (ALT) in the acetaminophen (APAP) overdose-induced acute liver injury model[2].

IC 50

LPA1 Receptor: 94 nM (IC50); LPA3 Receptor: 752 nM (IC50); LPA5 Receptor: 463 nM (IC50)

storage

Store at +4°C

H2L 5765834 Preparation Products And Raw materials

Raw materials

Preparation Products

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H2L 5765834 Suppliers

China 26 United Kingdom 1 United States 5 Global 32
SPIRO PHARMA
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-
Email
eric_feng1954@126.com
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China
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9248
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EMMX Biotechnology LLC
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888-539-0666
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888-539-0666
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info@emmx.com
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United States
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8447
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Shanghai YuanYe Biotechnology Co., Ltd.
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021-61312847; 18021002903
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QQ:3008007432
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3008007409@qq.com
Country
China
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86249
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MQ (shanghai) Pharmaceuticals Co., Ltd.
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13761635123
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1014988033@qq
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sales@linyuepharm.com
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China
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5562
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TargetMol Chemicals Inc.
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+1-781-999-5354; +17819995354
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marketing@targetmol.com
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United States
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32467
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Jinan Jiuli Biotechnology Co. , Ltd.
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15865264761
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486064515@qq.com
Country
China
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4885
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58
Hefei Mokai Pharmaceutical Technology Co., Ltd
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18130062233
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690231469@qq.com
Country
China
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8100
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58
Bide Pharmatech Ltd.
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400-1647117 13681763483
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product02@bidepharm.com
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China
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TargetMol Chemicals Inc.
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4008200310
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marketing@tsbiochem.com
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China
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24960
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Shanghai Maclean Biochemical Technology Co., LTD
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021-50706066 15221275939
Email
shenlinxing@macklin.cn
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China
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29680
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420841-84-5, H2L 5765834Related Search:


  • 2,3-Dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-1H-isoindole-5-carboxylic acid
  • H2L 5765834
  • HFYPTENHTPNXGP-UHFFFAOYSA-N
  • LPL Receptor,lysophosphatidic,inhibit,Lysophospholipid Receptor,Inhibitor,LPA,receptors,acid,H2L 5765834,H-2L 5765834
  • 1H-Isoindole-5-carboxylic acid, 2,3-dihydro-2-[3-(4-nitrophenoxy)phenyl]-1,3-dioxo-
  • 2-(3-(4-Nitrophenoxy)phenyl)-1,3-dioxoisoindoline-5-carboxylic acid
  • H2L 5765834, 10 mM in DMSO
  • 420841-84-5