Didodecylamine Property

Melting point:

45-49 °C

Boiling point:

265 °C / 27mmHg

Density 

0.8385 (estimate)

refractive index 

1.4641 (estimate)

storage temp. 

2-8°C

pka

pK1:10.99(+1) (25°C)

form 

crystal

color 

white

BRN 

1777050

InChI

InChI=1S/C24H51N/c1-3-5-7-9-11-13-15-17-19-21-23-25-24-22-20-18-16-14-12-10-8-6-4-2/h25H,3-24H2,1-2H3

InChIKey

MJCJUDJQDGGKOX-UHFFFAOYSA-N

SMILES

C(NCCCCCCCCCCCC)CCCCCCCCCCC

CAS DataBase Reference

3007-31-6(CAS DataBase Reference)

EPA Substance Registry System

1-Dodecanamine, N-dodecyl- (3007-31-6)

Safety

Hazard Codes 

Xi

Risk Statements 

36/38

Safety Statements 

26-36

WGK Germany 

3

F 

10-34

HS Code 

2921.19.6190

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P332+P313IF SKIN irritation occurs: Get medical advice/attention.

P337+P313IF eye irritation persists: Get medical advice/attention.

Didodecylamine Chemical Properties,Usage,Production

Description

Didodecylamine is a secondary amine. It is reported as standard amine enhancer and its dermal enhancement properties has been studied using in vitro diffusion cell techniques. Solidification point of dodecylamine has been reported to be 26.2°C.

Chemical Properties

white crystalline solid

Uses

Didodecylamine may be used:

• to promote the crystal growth of 2D nanosheets of GdOCl with approximately square cross sections
• to investigate the effect of alkyl chain length of amine on phase transfer of aqueous synthesized gold nanoparticles (AuNPs) from water to toluene
• in the preparation of novel class of liquid crystalline complexes, by the interaction of copper nitrate

Application

Didodecylamine may be used:
to promote the crystal growth of 2D nanosheets of GdOCl with approximately square cross sections
to investigate the effect of alkyl chain length of amine on phase transfer of aqueous synthesized gold nanoparticles (AuNPs) from water to toluene
in the preparation of novel class of liquid crystalline complexes, by the interaction of copper nitrate

General Description

Didodecylamine is a secondary amine. It is reported as standard amine enhancer and its dermal enhancement properties has been studied using in vitro diffusion cell techniques. Solidification point of dodecylamine has been reported to be 26.2°C.

Purification Methods

Crystallise the amine from EtOH/*C6H6 under N2, and store away from CO2. It provides two crystalline forms: an -form with m 44.4o and a -form with m 51.8o. The hydrochloride has m 207-208o(dec, from isoProOH), the hydroiodide has m 23.8-234o(dec, sealed capillary) and the nitrate has m 125.4-125.2o(dec. sealed capillary) when crystallised from MeOH/Me2CO. [Hoerr et al. J Am Chem Soc 65 328 1943, Hoerr & Harwood J Org Chem 16 779 1951, Beilstein 4 III 412, 4 IV 801.]