2-(trifluoroMethyl)-4H-chroMen-4-one
- Product Name
- 2-(trifluoroMethyl)-4H-chroMen-4-one
- CAS No.
- 151668-40-5
- Chemical Name
- 2-(trifluoroMethyl)-4H-chroMen-4-one
- Synonyms
- 2-trifluoromethyl-4-chromone;2-(trifluoroMethyl)-4H-chroMen-4-one;2-(Trifluoromethyl)-4H-1-benzopyran-4-one;4H-1-Benzopyran-4-one, 2-(trifluoromethyl)-
- CBNumber
- CB72703593
- Molecular Formula
- C10H5F3O2
- Formula Weight
- 214.14
- MOL File
- 151668-40-5.mol
2-(trifluoroMethyl)-4H-chroMen-4-one Property
- Melting point:
- 95.0-95.7 °C
- Boiling point:
- 200.8±40.0 °C(Predicted)
- Density
- 1.445±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- Appearance
- White to off-white Solid
Safety
- HS Code
- 2932990090
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- PC910374
- Product name
- 2-(Trifluoromethyl)-4H-1-benzopyran-4-one
- Purity
- >98%
- Packaging
- 100mg
- Price
- $304
- Updated
- 2021/12/16
- Product number
- 2H17-3-0D
- Product name
- 2-(Trifluoromethyl)-4H-1-benzopyran-4-one
- Purity
- 98.0%
- Packaging
- 100mg
- Price
- $335
- Updated
- 2021/12/16
- Product number
- PC910374
- Product name
- 2-(Trifluoromethyl)-4H-1-benzopyran-4-one
- Purity
- >98%
- Packaging
- 1g
- Price
- $731
- Updated
- 2021/12/16
- Product number
- 2H17-3-0D
- Product name
- 2-(Trifluoromethyl)-4H-1-benzopyran-4-one
- Purity
- 98.0%
- Packaging
- 1g
- Price
- $807
- Updated
- 2021/12/16
- Product number
- PC910374
- Product name
- 2-(Trifluoromethyl)-4H-1-benzopyran-4-one
- Purity
- >98%
- Packaging
- 5g
- Price
- $2142
- Updated
- 2021/12/16
2-(trifluoroMethyl)-4H-chroMen-4-one Chemical Properties,Usage,Production
Synthesis
118-93-4
407-25-0
151668-40-5
General procedure for the synthesis of 2-trifluoromethyl-4H-chromen-4-one from 2'-hydroxyacetophenone and trifluoroacetic anhydride: 2'-hydroxyacetophenone (0.01 mol) was dissolved in trifluoroacetic anhydride (0.02 mol), followed by addition of pyridine (0.01 mol) to the solution. The reaction mixture was heated and stirred at 80 °C for 3 hours. After completion of the reaction, it was cooled to room temperature and the reaction mixture was treated with 1 M hydrochloric acid (5 mL) and dichloromethane (5 mL), followed by thorough washing with distilled water. The organic layer was dried with anhydrous sodium sulfate, the solvent was removed by rotary evaporator and the residue was vacuum dried. The target product 2-trifluoromethyl-4H-chromen-4-one was isolated from the starting material by fast column chromatography using a hexane solution of 10% ethyl acetate as eluent if necessary.
References
[1] Tetrahedron Letters, 2011, vol. 52, # 13, p. 1436 - 1440
[2] Tetrahedron, 2014, vol. 70, # 5, p. 1077 - 1083
2-(trifluoroMethyl)-4H-chroMen-4-one Preparation Products And Raw materials
Raw materials
Preparation Products
2-(trifluoroMethyl)-4H-chroMen-4-one Suppliers
- Tel
- 025-86918202 4000255188
- Fax
- 86-025-86918232
- sales@pharmablock.com
- Country
- China
- ProdList
- 5000
- Advantage
- 55
- Tel
- 400-6009262 16621234537
- Fax
- 021-64823266
- chenyj@titansci.com
- Country
- China
- ProdList
- 14101
- Advantage
- 59
- Tel
- 021-11111111 11111111111
- Fax
- qq:546919421
- 546919421@qq.com
- Country
- China
- ProdList
- 3521
- Advantage
- 55
- Tel
- 13391076197
- tombiopharma@163.com
- Country
- China
- ProdList
- 4987
- Advantage
- 55
- Tel
- 021-021-021-31663258 13795219287
- Fax
- 021-31663258
- donghuanwen@126.com
- Country
- China
- ProdList
- 8816
- Advantage
- 58
- Tel
- 025-66113011 13155353615
- Fax
- (7)02557626880
- qzhang@aikonchem.com
- Country
- China
- ProdList
- 15394
- Advantage
- 58
- Tel
- 0371-55051623 18137891487
- Fax
- QQ：2853979817
- 2853979817@qq.com
- Country
- China
- ProdList
- 9988
- Advantage
- 58
- Tel
- 400-668-9898
- Fax
- 010-51582189
- service@3achem.com
- Country
- China
- ProdList
- 20557
- Advantage
- 58
- Tel
- 4009004166/18616739031 18616739031
- 3007523370@qq.com
- Country
- China
- ProdList
- 52687
- Advantage
- 58
- Tel
- 18916696128
- service@snowpharm.com
- Country
- China
- ProdList
- 1369
- Advantage
- 58