ethyl (N-benzylcarbaMoyl)acetate
- Product Name
- ethyl (N-benzylcarbaMoyl)acetate
- CAS No.
- 29689-63-2
- Chemical Name
- ethyl (N-benzylcarbaMoyl)acetate
- Synonyms
- Ethyl N-Benzylmalonamate;ethyl (N-benzylcarbaMoyl)acetate;N-Benzylmalonamic Acid Ethyl Ester;Ethyl 3-(benzylamino)-3-oxopropanoate;Ethyl 3-(Benzylamino)-3-oxopropionate;Ethyl 3-(Benzylamino)-3-oxopropionate >(N-Benzylcarbamoyl)acetic Acid Ethyl Ester;3- (benzylamino) -3-oxopropionate ethyl ester;3-(Benzylamino)-3-Oxopropionic Acid Ethyl Ester;Propanoic acid, 3-oxo-3-[(phenylmethyl)amino]-, ethyl ester
- CBNumber
- CB72705193
- Molecular Formula
- C12H15NO3
- Formula Weight
- 221.25
- MOL File
- 29689-63-2.mol
ethyl (N-benzylcarbaMoyl)acetate Property
- Melting point:
- 49.0 to 53.0 °C
- Boiling point:
- 169 °C(Press: 0.6 Torr)
- Density
- 1.119±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- soluble in Methanol
- form
- powder to crystal
- pka
- 9.05±0.50(Predicted)
- color
- White to Light yellow
Safety
- HS Code
- 2924.29.7790
N-Bromosuccinimide Price
- Product number
- E1098
- Product name
- Ethyl 3-(Benzylamino)-3-oxopropionate
- Purity
- >98.0%(GC)
- Packaging
- 1g
- Price
- $94
- Updated
- 2024/03/01
- Product number
- E1098
- Product name
- Ethyl 3-(Benzylamino)-3-oxopropionate
- Purity
- >98.0%(GC)
- Packaging
- 5g
- Price
- $376
- Updated
- 2024/03/01
- Product number
- B126703
- Product name
- ethyl3-(benzylamino)-3-oxopropanoate
- Packaging
- 50mg
- Price
- $45
- Updated
- 2021/12/16
- Product number
- 5816AL
- Product name
- 3-(Benzylamino)-3-oxopropionicacidethylester
- Packaging
- 100mg
- Price
- $77
- Updated
- 2021/12/16
- Product number
- A182488
- Product name
- Ethyl3-(benzylamino)-3-oxopropanoate
- Purity
- 97%
- Packaging
- 100mg
- Price
- $13
- Updated
- 2021/12/16
ethyl (N-benzylcarbaMoyl)acetate Chemical Properties,Usage,Production
Synthesis
36239-09-5
100-46-9
29689-63-2
16a) Synthesis of ethyl 3-oxo-3-[(phenylmethyl)amino]propanoate: In a dry reaction flask, benzylamine (1.10 g, 10.3 mmol) and ethylmalonyl chloride (1.29 mL, 10.3 mmol) were dissolved in dichloromethane (10 mL), followed by triethylamine (1.44 mL, 10.3 mmol). The reaction mixture was stirred at room temperature for 1 hour. After completion of the reaction, the reaction mixture was diluted with saturated aqueous sodium bicarbonate and extracted with ethyl acetate (3 x 20 mL). The organic phases were combined, dried with anhydrous magnesium sulfate, filtered and concentrated under reduced pressure to give ethyl 3-(phenylmethylamino)-3-oxopropanoate as a yellow oil (2.27 g, 100% yield). The product was confirmed by 1H NMR (400 MHz, chloroform-d): δ 7.55 (broad single peak, 1H), 7.24-7.36 (multiple peaks, 5H), 4.45 (double peak, J = 5.6 Hz, 2H), 4.17 (quartet peak, J = 7.2 Hz, 2H), 3.31 (single peak, 2H), 1.27 (triple peak, J = 7.2 Hz, 3H). The mass spectrum (ES+) showed m/e 222 [M + H]+.
References
[1] Patent: US2007/213335, 2007, A1. Location in patent: Page/Page column 14
[2] Patent: US4663319, 1987, A
[3] Journal of Organic Chemistry, 1985, vol. 50, # 25, p. 5223 - 5230
ethyl (N-benzylcarbaMoyl)acetate Preparation Products And Raw materials
Raw materials
Preparation Products
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