3-BroMo-2,6-diMetylaniline
- Product Name
- 3-BroMo-2,6-diMetylaniline
- CAS No.
- 53874-26-3
- Chemical Name
- 3-BroMo-2,6-diMetylaniline
- Synonyms
- 3-BroMo-2,6-diMetylaniline;3-Bromo-2,6-dimethylaniline;3-bromo-2,6-dimethylbenzenamine;Benzenamine, 3-bromo-2,6-dimethyl-
- CBNumber
- CB72705744
- Molecular Formula
- C8H10BrN
- Formula Weight
- 200.08
- MOL File
- 53874-26-3.mol
3-BroMo-2,6-diMetylaniline Property
- Boiling point:
- 273.7±35.0 °C(Predicted)
- Density
- 1.424±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C, protect from light
- pka
- 3.23±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
Safety
- HS Code
- 2921490090
N-Bromosuccinimide Price
- Product number
- B682248
- Product name
- 3-Bromo-2,6-dimethylaniline
- Packaging
- 50mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- FB160355
- Product name
- 3-Bromo-2,6-dimethylaniline
- Packaging
- 250mg
- Price
- $237.5
- Updated
- 2021/12/16
- Product number
- FB160355
- Product name
- 3-Bromo-2,6-dimethylaniline
- Packaging
- 500mg
- Price
- $365
- Updated
- 2021/12/16
- Product number
- 3730-9-18
- Product name
- 3-Bromo-2,6-dimethylaniline
- Packaging
- 500mg
- Price
- $472
- Updated
- 2021/12/16
- Product number
- 1144CU
- Product name
- 3-Bromo-2,6-dimethylaniline
- Packaging
- 1g
- Price
- $532
- Updated
- 2021/12/16
3-BroMo-2,6-diMetylaniline Chemical Properties,Usage,Production
Synthesis
39053-43-5
53874-26-3
General procedure for the synthesis of 3-bromo-2,6-dimethylaniline from 1-bromo-2,4-dimethyl-3-nitrobenzene: 1-bromo-2,4-dimethyl-3-nitrobenzene (2.66 g, 11.6 mmol) was dissolved in acetic acid (48 mL) under stirring conditions, followed by the addition of iron powder (2.58 g, 46.3 mmol). The reaction mixture was heated at 80 °C for 18 hours. After completion of the reaction, it was cooled to room temperature and filtered. The filtrate was concentrated to dryness under reduced pressure and the resulting residue was alkalized with aqueous sodium hydroxide and then extracted three times with ethyl acetate. The organic phases were combined and dried with anhydrous magnesium sulfate. The dried organic phase was concentrated to dryness under reduced pressure. The crude product was purified by fast column chromatography using a gradient elution of 0-30% ethyl acetate in hexane to afford the target product 3-bromo-2,6-dimethylaniline (1.28 g, 6.40 mmol, 55.3% yield).
References
[1] Journal of Medicinal Chemistry, 2018, vol. 61, # 16, p. 7202 - 7217
[2] Patent: WO2015/79251, 2015, A1. Location in patent: Paragraph 00215
[3] Patent: KR2015/124677, 2015, A. Location in patent: Paragraph 0334; 0339-0342
[4] Patent: WO2009/44311, 2009, A1. Location in patent: Page/Page column 39
3-BroMo-2,6-diMetylaniline Preparation Products And Raw materials
Raw materials
Preparation Products
3-BroMo-2,6-diMetylaniline Suppliers
- Tel
- 028-82729560 18030702676
- Fax
- 028-82729560
- sales@yuehepharm.com
- Country
- China
- ProdList
- 183
- Advantage
- 58
- Tel
- 20-66003216 18666003216
- Fax
- +86-20-28069063
- info@porsefinechemical.com
- Country
- China
- ProdList
- 1941
- Advantage
- 62
- Tel
- 028-87078428 028-87074958
- Fax
- 8772-8116
- chengzhenyong@cdfirster.com
- Country
- China
- ProdList
- 2598
- Advantage
- 60
- Tel
- sales@ahpharmatech.com
- Country
- China
- ProdList
- 5734
- Advantage
- 55
- Tel
- 13764913901
- Fax
- -
- info@angtibio.com
- Country
- China
- ProdList
- 4977
- Advantage
- 55
- Tel
- 025-84112752 13805181430
- Fax
- +86-25-84846489
- 154301870@qq.com
- Country
- China
- ProdList
- 998
- Advantage
- 55
- Tel
- 0371-0371-55629727 13323845623
- Fax
- 037155629727
- 2885676761@qq.com
- Country
- China
- ProdList
- 10050
- Advantage
- 58
- Tel
- 571-89925085
- Fax
- 0086-571-89925065
- sales@amadischem.com
- Country
- China
- ProdList
- 131957
- Advantage
- 58
- Tel
- +86-（0）57185586718; +8613336195806
- Fax
- +86-571-85864795
- sales@capot.com
- Country
- China
- ProdList
- 29735
- Advantage
- 60
- Tel
- 025-58859352 18068836627
- Fax
- (5)02557626880
- dt3@aikonchem.com
- Country
- China
- ProdList
- 15491
- Advantage
- 58
View Lastest Price from 3-BroMo-2,6-diMetylaniline manufacturers
- Product
- 3-BroMo-2,6-diMetylaniline 53874-26-3
- Price
- US $1.00/KG
- Min. Order
- 1g
- Purity
- 99.0%
- Supply Ability
- 100kg
- Release date
- 2020-01-10