2-Propylthiazolo[4,5-c]quinolin-4-aMine
- Product Name
- 2-Propylthiazolo[4,5-c]quinolin-4-aMine
- CAS No.
- 256922-53-9
- Chemical Name
- 2-Propylthiazolo[4,5-c]quinolin-4-aMine
- Synonyms
- CL075;CL075 >=98% (HPLC);CL075, 10 mM in DMSO;2-Propylthiazolo[4,5-c]quinolin-4-aMine;Thiazolo[4,5-c]quinolin-4-amine, 2-propyl-
- CBNumber
- CB72712953
- Molecular Formula
- C13H13N3S
- Formula Weight
- 243.33
- MOL File
- 256922-53-9.mol
2-Propylthiazolo[4,5-c]quinolin-4-aMine Property
- Boiling point:
- 440.1±25.0 °C(Predicted)
- Density
- 1.313±0.06 g/cm3(Predicted)
- storage temp.
- 2-8°C
- solubility
- Soluble in DMSO
- pka
- 4.23±0.50(Predicted)
- form
- powder
- color
- white to beige
- InChI
- 1S/C13H13N3S/c1-2-5-10-16-11-12(17-10)8-6-3-4-7-9(8)15-13(11)14/h3-4,6-7H,2,5H2,1H3,(H2,14,15)
- InChIKey
- NFYMGJSUKCDVJR-UHFFFAOYSA-N
- SMILES
- [s]1c2c(nc1CCC)c(nc3c2cccc3)N
Safety
- WGK Germany
- WGK 3
- Storage Class
- 11 - Combustible Solids
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- SML2235
- Product name
- CL075
- Purity
- ≥98% (HPLC)
- Packaging
- 5mg
- Price
- $118
- Updated
- 2026/03/19
- Product number
- SML2235
- Product name
- CL075
- Purity
- ≥98% (HPLC)
- Packaging
- 25mg
- Price
- $455
- Updated
- 2026/03/19
- Product number
- 6142
- Product name
- CL075
- Purity
- ≥98%(HPLC)
- Packaging
- 5
- Price
- $187
- Updated
- 2021/12/16
- Product number
- C560005
- Product name
- CL075
- Packaging
- 5mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- CS-0063631
- Product name
- CL075
- Purity
- ≥99.0%
- Packaging
- 1mg
- Price
- $180
- Updated
- 2021/12/16
2-Propylthiazolo[4,5-c]quinolin-4-aMine Chemical Properties,Usage,Production
Uses
CL075 has been used to activate the monocyte-derived dendritic cells (DCs) to demonstrate the ability of DCs to induce cell death.
Biological Activity
CL075 is a selective agonist of Toll-like receptor-8 (TLR-8) with immunostimulant activity. It showed an EC50 value of 400nM for IRF-NFΚB stimulation in TLR8 compared to 4 μM for TLR7.', 'CL075 is a thiazoloquinolone derivative. It might influence tumor development.
in vivo
CL075 (5 μM (0.5 mL); s.c.) activates a mild antigen-specific antibody response in rabbits[1].
IC 50
TLR8
storage
Store at +4°C
2-Propylthiazolo[4,5-c]quinolin-4-aMine Preparation Products And Raw materials
Raw materials
Preparation Products
2-Propylthiazolo[4,5-c]quinolin-4-aMine Suppliers
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