4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol

Product Name: 4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol
CAS No.: 1394820-98-4
Chemical Name: 4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol
Synonyms: 112685;4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol;7-Quinolinol, 4-(2-fluoro-4-nitrophenoxy)-;7-Hydroxy-4-(2-fluoro-4-nitrophenoxy)quinoline;4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol hydrochloride
CBNumber: CB72718344
Molecular Formula: C15H9FN2O4
Formula Weight: 300.24
MOL File: 1394820-98-4.mol

More

Less

4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol Property

Boiling point:: 467.4±45.0 °C(Predicted)
Density: 1.487±0.06 g/cm3(Predicted)
storage temp.: Sealed in dry,Room Temperature
pka: 8.46±0.40(Predicted)
InChI: InChI=1S/C15H9FN2O4/c16-12-7-9(18(20)21)1-4-15(12)22-14-5-6-17-13-8-10(19)2-3-11(13)14/h1-8,19H
InChIKey: ORSCRIJOVRKFEO-UHFFFAOYSA-N
SMILES: N1C2C(=CC=C(O)C=2)C(OC2=CC=C([N+]([O-])=O)C=C2F)=CC=1

More

Less

Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

More

Less

N-Bromosuccinimide Price

AK Scientific

Product number: 5401EM
Product name: 4-(2-Fluoro-4-nitrophenoxy)quinolin-7-ol
Packaging: 1g
Price: $146
Updated: 2021/12/16

Matrix Scientific

Product number: 121002
Product name: 4-(2-Fluoro-4-nitrophenoxy)quinolin-7-ol
Purity: 97%
Packaging: 250mg
Price: $2070
Updated: 2021/12/16

Matrix Scientific

Product number: 121002
Product name: 4-(2-Fluoro-4-nitrophenoxy)quinolin-7-ol
Purity: 97%
Packaging: 1g
Price: $4500
Updated: 2021/12/16

Ambeed

Product number: A207079
Product name: 4-(2-Fluoro-4-nitrophenoxy)quinolin-7-ol
Purity: 95+%
Packaging: 100mg
Price: $17
Updated: 2021/12/16

Ambeed

Product number: A207079
Product name: 4-(2-Fluoro-4-nitrophenoxy)quinolin-7-ol
Purity: 95+%
Packaging: 250mg
Price: $26
Updated: 2021/12/16

More

Less

4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol Chemical Properties,Usage,Production

Synthesis

1394820-97-3

1394820-98-4

Step 5) Synthesis of 4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol: 7-(benzyloxy)-4-(2-fluoro-4-nitrophenoxy)quinoline (100 g, 256.4 mmol) was suspended in dioxane (425 mL) and concentrated hydrochloric acid (425 mL, 5.1 mol) was added. The reaction mixture was stirred at 100 °C for 24 hours. Upon completion of the reaction, the mixture was cooled to room temperature and the precipitated solid was collected by filtration. The resulting solid was suspended in anhydrous ethanol (100 mL), stirred and the solid was collected by filtration again. Finally, the solid was dried under vacuum at 60 °C for 12 h to give the title compound as a light-colored solid (73.3 g, 85% yield). m/z MS (ESI, cationic): 301 [M +1]+; 1H NMR (400 MHz, DMSO-d6): δ 7.06-7.07 (d, J = 6.8 Hz, 1H), 7.51-7.54 (m 1H), 7.71 (s, 1H), 7.89-7.94 (m, 1H), 8.28-8.30 (d, J = 8.8 Hz, 1H), 8.41-8.43 (d, J = 9.6 Hz, 1H), 8.51-8.54 (d, J = 10 Hz, 1H), 8.94-8.96 (d, J = 6.4 Hz, 1H), and 12.00 (s, 1H).

References

[1] Patent: US2012/219522, 2012, A1. Location in patent: Page/Page column 20
[2] Journal of Medicinal Chemistry, 2018, vol. 61, # 14, p. 6277 - 6292

4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol Preparation Products And Raw materials

Raw materials

Preparation Products

More

Less

4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol Suppliers

China 27 India 1 United States 3 Global 31

Jinan Zhouxing Pharmaceutical Technology Co.,Ltd.

Tel: 0531-88026181 15253191047
Fax: -
Email: 705452127@qq.com
Country: China
ProdList: 87
Advantage: 58

Adamas Reagent, Ltd.

Tel: 400-6009262 16621234537
Fax: 021-64823266
Email: chenyj@titansci.com
Country: China
ProdList: 14101
Advantage: 59

Nanjing XiLang Chemical Products Co., Ltd.

Tel: 18936048580
Email: chemxilang@163.com
Country: China
ProdList: 3909
Advantage: 58

Amadis Chemical Company Limited

Tel: 571-89925085
Fax: 0086-571-89925065
Email: sales@amadischem.com
Country: China
ProdList: 131957
Advantage: 58

Aikon International Limited

Tel: 025-66113011 13155353615
Fax: (7)02557626880
Email: qzhang@aikonchem.com
Country: China
ProdList: 15394
Advantage: 58

Guangzhou Anyanren Pharmaceutical Technology Co., Ltd.

Tel: 18028661570
Email: 2412659056@qq.com
Country: China
ProdList: 291
Advantage: 58

Guangdong Wengjiang Chemical Reagent Co., Ltd.

Tel: 0751-2886766 13927870850
Fax: 0751-2886756
Email: 3001267247@qq.com
Country: China
ProdList: 9941
Advantage: 58

Guangzhou Yuheng Pharmaceutical Technology Co., Ltd

Tel: +8613580539051
Email: joe@yuhengpharm.com
Country: CHINA
ProdList: 21142
Advantage: 58

Zhengzhou Alpha Chemical Co. LTD

Tel: 0371-0371-53732842 13383863444
Fax: QQ：3002612166
Email: 3002612166@qq.com
Country: China
ProdList: 9996
Advantage: 58

Shanghai Dexuan Pharmaceutical Technology Co., Ltd

Tel: 1701086315
Fax: 1701086315@qq.com
Email: dexuanpharma@126.com
Country: China
ProdList: 9475
Advantage: 58

1394820-98-4, 4-(2-fluoro-4-nitrophenoxy)quinolin-7-olRelated Search:

4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol

112685

4-(2-fluoro-4-nitrophenoxy)quinolin-7-ol hydrochloride

7-Quinolinol, 4-(2-fluoro-4-nitrophenoxy)-

7-Hydroxy-4-(2-fluoro-4-nitrophenoxy)quinoline

1394820-98-4