ChemicalBook > CAS DataBase List > 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-
2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-
- Product Name
- 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-
- CAS No.
- 1564266-54-1
- Chemical Name
- 2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-
- Synonyms
- Saxagliptin Impurity 28;(1R,3R,5R)-2-Boc-3-carbamoyl-2-azabicyclo[3.1.0]hexane;(1R, 3R, 5R) -3-(aminocarbonyl) -2-aza bicyclic [3.1.0] hexane-2-tert-butyl formate;2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)-
- CBNumber
- CB72723034
- Molecular Formula
- C11H18N2O3
- Formula Weight
- 226.27
- MOL File
- 1564266-54-1.mol
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2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- Property
- Boiling point:
- 388.9±21.0 °C(Predicted)
- Density
- 1.228±0.06 g/cm3(Predicted)
- pka
- 16.00±0.20(Predicted)
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N-Bromosuccinimide Price
TRC
- Product number
- B692930
- Product name
- tert-Butyl(1R,3R,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate
- Packaging
- 50mg
- Price
- $1230
- Updated
- 2021/12/16
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2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- Chemical Properties,Usage,Production
Uses
tert-Butyl (1R,3R,5R)-3-Carbamoyl-2-azabicyclo[3.1.0]hexane-2-carboxylate is an intermediate in the synthesis of (2’R,2R,cis)-Saxagliptin (S143475), which is an impurity of Saxagliptin (S143500). Saxagliptin is a potent and selective reversible inhibitor of dipeptidyl peptidase-4 (DPP-IV) developed for the treatment of type 2 diabetes.
2-Azabicyclo[3.1.0]hexane-2-carboxylic acid, 3-(aMinocarbonyl)-, 1,1-diMethylethyl ester, (1R,3R,5R)- Preparation Products And Raw materials
Raw materials
Preparation Products
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