ChemicalBook > CAS DataBase List > 1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-

1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-

Product Name
1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-
CAS No.
1334179-85-9
Chemical Name
1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-
Synonyms
BTTAA;inhibit,Inhibitor,BTTAA;(4-{[Bis-(1-tert-butyl-1H-[1,2,3]triazol-4-ylmethyl)-amino]-methyl}-[1,2,3]triazol-1-yl)-acetic acid;2-(4-((Bis(2,2-dimethyl-1-(1H-1,2,3-triazol-4-yl)propyl)amino)methyl)-1H-1,2,3-triazol-1-yl)aceticacid;2-(4-((bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid;1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-;(4-((Bis((1-(2-methyl-2-propyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid;{4-[(Bis{[1-(2-methyl-2-propanyl)-1H-1,2,3-triazol-4-yl]methyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetic acid;(4-{[Bis-(1-tert-butyl-1H-[1,2,3]triazol-4-ylmethyl)-amino]-methyl}-[1,2,3]triazol-1-yl)-acetic acid (other name: BTTAA)
CBNumber
CB72730768
Molecular Formula
C19H30N10O2
Formula Weight
430.51
MOL File
1334179-85-9.mol
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1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- Property

Boiling point:
620.7±65.0 °C(Predicted)
Density 
1.32±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Soluble in DMSO, DMF, MeOH
pka
3.33±0.10(Predicted)
form 
Solid
color 
White to off-white
InChI
InChI=1S/C19H30N10O2/c1-18(2,3)28-11-15(21-24-28)8-26(7-14-10-27(23-20-14)13-17(30)31)9-16-12-29(25-22-16)19(4,5)6/h10-12H,7-9,13H2,1-6H3,(H,30,31)
InChIKey
MGQYHUDOWOGSQI-UHFFFAOYSA-N
SMILES
N1(CC(O)=O)C=C(CN(CC2=CN(C(C)(C)C)N=N2)CC2=CN(C(C)(C)C)N=N2)N=N1
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H242Heating may cause a fire

Precautionary statements

P210Keep away from heat/sparks/open flames/hot surfaces. — No smoking.

P234Keep only in original container.

P235Keep cool.

P240Ground/bond container and receiving equipment.

P370+P378In case of fire: Use … for extinction.

P403Store in a well-ventilated place.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
906328
Product name
BTTAA
Purity
≥95%
Packaging
100mg
Price
$255
Updated
2024/03/01
Sigma-Aldrich
Product number
906328
Product name
BTTAA
Purity
≥95%
Packaging
500mg
Price
$545.4
Updated
2024/03/01
Biorbyt Ltd
Product number
orb611468
Product name
BTTAA
Packaging
5mg
Price
$569.5
Updated
2021/12/16
Chem-Impex
Product number
35127
Product name
BTTAA,95%(HPLC)
Purity
95%(HPLC)
Packaging
250MG
Price
$582.4
Updated
2021/12/16
Chem-Impex
Product number
35127
Product name
BTTAA,95%(HPLC)
Purity
95%(HPLC)
Packaging
100MG
Price
$291.2
Updated
2021/12/16
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1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- Chemical Properties,Usage,Production

Description

BTTP is a newest generation, accelerating ligand for CuAAC that provides much greater rate enhancement compared to previous generation ligands (e.g. THPTA or TBTA). More importantly, it minimizes perturbations to the physiological state of the cells or organisms probed and allows for effective bioconjugation with suppressed cell cytotoxicity by further lowering copper loading in the catalyst formulation. Nature Communications. 5: 4981(2014) Chem Asian J., 6(10), 2796-802(2011)

Uses

BTTAA is a next-generation, water-soluble ligand for the copper(I)-catalyzed azide-alkyne cycloaddition (CuAAC) that dramatically accelerates reaction rates and suppresses cell cytotoxicity. The biocompatibility and fast kinetics of BTTAA are advancements from water-insoluble TBTA and are desirable for bio conjugation in diverse chemical biology experiments.

1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- Preparation Products And Raw materials

Raw materials

Preparation Products

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1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- Suppliers

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View Lastest Price from 1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]- manufacturers

Xian confluore Biological Technology Co., Ltd.
Product
BTTAA 1334179-85-9
Price
US $0.00/mg
Min. Order
100mg
Purity
>95.00%
Supply Ability
100mg
Release date
2024-03-22

1334179-85-9, 1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-Related Search:


  • 1H-1,2,3-Triazole-1-acetic acid, 4-[[bis[[1-(1,1-diMethylethyl)-1H-1,2,3-triazol-4-yl]Methyl]aMino]Methyl]-
  • (4-{[Bis-(1-tert-butyl-1H-[1,2,3]triazol-4-ylmethyl)-amino]-methyl}-[1,2,3]triazol-1-yl)-acetic acid
  • BTTAA
  • (4-{[Bis-(1-tert-butyl-1H-[1,2,3]triazol-4-ylmethyl)-amino]-methyl}-[1,2,3]triazol-1-yl)-acetic acid (other name: BTTAA)
  • {4-[(Bis{[1-(2-methyl-2-propanyl)-1H-1,2,3-triazol-4-yl]methyl}amino)methyl]-1H-1,2,3-triazol-1-yl}acetic acid
  • 2-(4-((bis((1-(tert-butyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid
  • 2-(4-((Bis(2,2-dimethyl-1-(1H-1,2,3-triazol-4-yl)propyl)amino)methyl)-1H-1,2,3-triazol-1-yl)aceticacid
  • inhibit,Inhibitor,BTTAA
  • (4-((Bis((1-(2-methyl-2-propyl)-1H-1,2,3-triazol-4-yl)methyl)amino)methyl)-1H-1,2,3-triazol-1-yl)acetic acid
  • 1334179-85-9
  • C19H30N10O2