ChemicalBook > CAS DataBase List > HUHS015

HUHS015

Product Name
HUHS015
CAS No.
1453097-13-6
Chemical Name
HUHS015
Synonyms
HUHS015;HUHS-015;HUHS 015;HUHS015, 10 mM in DMSO;4-Benzyl-3-methyl-1-(6-methyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-5-ol;1H-Pyrazol-5-ol, 3-methyl-1-(6-methyl-1H-benzimidazol-2-yl)-4-(phenylmethyl)-;prostate,ALKBH3,antigen-1,HUHS015,HUHS 015,PCA-1,inhibit,HUHS-015,Inhibitor,cancer
CBNumber
CB72731068
Molecular Formula
C19H18N4O
Formula Weight
318.37
MOL File
1453097-13-6.mol
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HUHS015 Property

Boiling point:
585.2±42.0 °C(Predicted)
Density 
1.30±0.1 g/cm3(Predicted)
storage temp. 
Store at -20°C
solubility 
DMSO:34.0(Max Conc. mg/mL);106.79(Max Conc. mM)
form 
A crystalline solid
pka
8.12±0.50(Predicted)
color 
White to off-white
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Usbiological
Product number
451987
Product name
HUHS 015
Packaging
10mg
Price
$460
Updated
2021/12/16
TRC
Product number
H673490
Product name
HUHS015
Packaging
50mg
Price
$765
Updated
2021/12/16
Crysdot
Product number
CD31003431
Product name
HUHS015
Purity
98+%
Packaging
5mg
Price
$245
Updated
2021/12/16
Crysdot
Product number
CD31003431
Product name
HUHS015
Purity
98+%
Packaging
10mg
Price
$350
Updated
2021/12/16
Crysdot
Product number
CD31003431
Product name
HUHS015
Purity
98+%
Packaging
50mg
Price
$1050
Updated
2021/12/16
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HUHS015 Chemical Properties,Usage,Production

Uses

HUHS 015 is used in preparation of arylpyrazolol derivatives as antigen-1 (PCA-1/ALKBH3) inhibitors for anti-prostate cancer drugs.

in vivo

HUHS015 potently suppresses the growth of DU145 cells in a mouse xenograft model[1].
HUHS015 displays 7.2% bioavailability (BA) in rats after oral administration[1].

Animal Model:Nude mice[1]
Dosage:32 mg/kg
Administration:Subcutaneous injection; daily; 6 days
Result:Has inhibitory effect on the growth of subcutaneously implanted DU145, without limiting weight gains after a 6 days continuous administration.

HUHS015 Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from HUHS015 manufacturers

Career Henan Chemical Co
Product
HUHS015 1453097-13-6
Price
US $1.00/KG
Min. Order
1KG
Purity
97%-99.9%
Supply Ability
100kg
Release date
2019-12-25

1453097-13-6, HUHS015Related Search:


  • HUHS015
  • 4-Benzyl-3-methyl-1-(6-methyl-1H-benzo[d]imidazol-2-yl)-1H-pyrazol-5-ol
  • HUHS-015;HUHS 015
  • 1H-Pyrazol-5-ol, 3-methyl-1-(6-methyl-1H-benzimidazol-2-yl)-4-(phenylmethyl)-
  • prostate,ALKBH3,antigen-1,HUHS015,HUHS 015,PCA-1,inhibit,HUHS-015,Inhibitor,cancer
  • HUHS015, 10 mM in DMSO
  • 1453097-13-6