(2,6-dibroMo-4-fluorophenyl)Methanol
- Product Name
- (2,6-dibroMo-4-fluorophenyl)Methanol
- CAS No.
- 1346674-69-8
- Chemical Name
- (2,6-dibroMo-4-fluorophenyl)Methanol
- Synonyms
- 2,6-Dibromo-4-fluorobenzyl Alcohol;2,6-Dibromo-4-fluorobenzenemethanol;(2,6-dibroMo-4-fluorophenyl)Methanol;Benzenemethanol, 2,6-dibromo-4-fluoro-;(2,6-Dibromo-4-fluorophenyl)methanol 97%
- CBNumber
- CB72736715
- Molecular Formula
- C7H5Br2FO
- Formula Weight
- 283.92
- MOL File
- 1346674-69-8.mol
(2,6-dibroMo-4-fluorophenyl)Methanol Property
- Boiling point:
- 311.9±37.0 °C(Predicted)
- Density
- 2.030±0.06 g/cm3(Predicted)
- storage temp.
- Sealed in dry,Room Temperature
- pka
- 13.46±0.10(Predicted)
- Appearance
- Pale purple to purple Solid
- InChI
- InChI=1S/C7H5Br2FO/c8-6-1-4(10)2-7(9)5(6)3-11/h1-2,11H,3H2
- InChIKey
- FQRVRSIZRGCUQG-UHFFFAOYSA-N
- SMILES
- C1(CO)=C(Br)C=C(F)C=C1Br
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P264Wash hands thoroughly after handling.
P264Wash skin thouroughly after handling.
P270Do not eat, drink or smoke when using this product.
P280Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P321Specific treatment (see … on this label).
P330Rinse mouth.
P332+P313IF SKIN irritation occurs: Get medical advice/attention.
P362Take off contaminated clothing and wash before reuse.
P501Dispose of contents/container to..…
N-Bromosuccinimide Price
- Product number
- D472395
- Product name
- (2,6-Dibromo-4-Fluorophenyl)Methanol
- Packaging
- 100mg
- Price
- $175
- Updated
- 2021/12/16
- Product number
- PC53089
- Product name
- (2,6-Dibromo-4-fluorophenyl)methanol
- Purity
- 97%
- Packaging
- 250mg
- Price
- $209
- Updated
- 2021/12/16
- Product number
- CS-W000480
- Product name
- (2,6-DIBROMO-4-FLUOROPHENYL)METHANOL
- Packaging
- 100mg
- Price
- $229
- Updated
- 2021/12/16
- Product number
- 2601-B-27
- Product name
- (2,6-Dibromo-4-fluorophenyl)methanol
- Packaging
- 250mg
- Price
- $231
- Updated
- 2021/12/16
- Product number
- PC53089
- Product name
- (2,6-Dibromo-4-fluorophenyl)methanol
- Purity
- 97%
- Packaging
- 1g
- Price
- $520
- Updated
- 2021/12/16
(2,6-dibroMo-4-fluorophenyl)Methanol Chemical Properties,Usage,Production
Synthesis
938467-02-8
1346674-69-8
The general procedure for synthesizing 2,6-dibromo-4-fluorobenzaldehyde from 2,6-dibromo-4-fluorobenzenemethanol was as follows: in Example 101b, 2,6-dibromo-4-fluorobenzaldehyde (20 g, 71 mmol) was dissolved in ethanol (500 mL) and NaBH4 (10 g, 284 mmol) was added. The reaction mixture was stirred at room temperature (~10 °C) for 4 h. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm complete consumption of the raw materials. Upon completion of the reaction, the reaction was quenched with 1 M HCl solution (150 mL). Subsequently, most of the ethanol was evaporated under reduced pressure. The residue was extracted with ethyl acetate (3 x 500 mL) and the organic layers were combined and dried with anhydrous Na2SO4. After drying, the organic solvent was evaporated under vacuum. Finally, the residue was purified by silica gel column chromatography (eluent was petroleum ether/ethyl acetate in a gradient from 50:1 to 20:1) to afford the target product 2,6-dibromo-4-fluorobenzenemethanol (15 g, 75% yield) as a white solid.
References
[1] Patent: US2013/116245, 2013, A1. Location in patent: Paragraph 0188; 0189
[2] Patent: US2013/116245, 2013, A1. Location in patent: Paragraph 0245
[3] Patent: US2013/116262, 2013, A1. Location in patent: Paragraph 0212
[4] ACS Medicinal Chemistry Letters, 2017, vol. 8, # 6, p. 608 - 613
(2,6-dibroMo-4-fluorophenyl)Methanol Preparation Products And Raw materials
Raw materials
Preparation Products
(2,6-dibroMo-4-fluorophenyl)Methanol Suppliers
- Tel
- 029-86115547 17791676824
- Fax
- 021-51602123
- sales@cochemical.com
- Country
- China
- ProdList
- 4104
- Advantage
- 58
- Tel
- 021-20958197 20965099
- Fax
- 021-20960837
- sales@skychemical.com
- Country
- China
- ProdList
- 1183
- Advantage
- 57
- Tel
- 400-400-164-7117 18317119277
- Fax
- +86-21-61629029
- product02@bidepharm.com
- Country
- China
- ProdList
- 40000
- Advantage
- 60
- Tel
- 010-56330744 18310155299
- Fax
- 010-56330744
- sales@labter.com.cn
- Country
- China
- ProdList
- 20000
- Advantage
- 55
- Tel
- 15332490153
- Fax
- QQ 2725398181
- newprochem@126.com
- Country
- China
- ProdList
- 991
- Advantage
- 55
- Tel
- 027-59207879 1972026995 18140587686
- Fax
- QQ：1972026995
- sales@3600chem.com
- Country
- China
- ProdList
- 4396
- Advantage
- 55
- Tel
- 21-619849051-1 18521059765
- synchempharma@aliyun.com
- Country
- China
- ProdList
- 4963
- Advantage
- 55
- Tel
- 13918644899
- Fax
- -
- tianchong009@hotmail.com
- Country
- China
- ProdList
- 1994
- Advantage
- 55
- Tel
- 021-20960837,QQ1332204249
- Fax
- 021-20960837
- sales@skychemical.com
- Country
- China
- ProdList
- 3341
- Advantage
- 55
- Tel
- 18511709189
- Fax
- 010-58043593
- sales@hechemist.com
- Country
- China
- ProdList
- 2835
- Advantage
- 58
View Lastest Price from (2,6-dibroMo-4-fluorophenyl)Methanol manufacturers
- Product
- (2,6-dibromo-4-fluorophenyl)methanol 1346674-69-8
- Price
- US $0.00/kg
- Min. Order
- 20kg
- Purity
- 99%
- Supply Ability
- 20 tons
- Release date
- 2025-04-08