ChemicalBook > CAS DataBase List > 135270-13-2

135270-13-2

Product Name
135270-13-2
CAS No.
135270-13-2
Chemical Name
135270-13-2
Synonyms
Efinaconazole Impurity 2;Efinaconazole Epoxy Impurity;Efinaconazole Related Impurity;Efinaconazole Related Impurity 6;1-[[(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-oxiranyl]methyl]-1H-1,2,4-triazole;1-(((2R,3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole;1H-1,2,4-Triazole, 1-[[(2R,3R)-2-(2,4-difluorophenyl)-3-methyl-2-oxiranyl]methyl]-;1-(((2R,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity)
CBNumber
CB72742811
Molecular Formula
C12H11F2N3O
Formula Weight
251.23
MOL File
135270-13-2.mol
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135270-13-2 Property

Boiling point:
371.6±52.0 °C(Predicted)
Density 
1.41±0.1 g/cm3(Predicted)
pka
2.75±0.10(Predicted)
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC
Product number
D447060
Product name
(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane
Packaging
1mg
Price
$185
Updated
2021/12/16
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135270-13-2 Chemical Properties,Usage,Production

Uses

(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-[(1H-1,2,4-triazol-1-yl)methyl]oxirane is a useful synthetic intermediate in the synthesis of (2R,3S)-Efinaconazole (E435080); the 2R,3S-enantiomer of Efinaconazole (E435070) which is a topical antifungal for onychomycosis.

135270-13-2 Preparation Products And Raw materials

Raw materials

Preparation Products

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135270-13-2, 135270-13-2Related Search:


  • 1-(((2R,3R)-2-(2,4-difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole
  • Efinaconazole Related Impurity 6
  • 1-[[(2R,3R)-2-(2,4-Difluorophenyl)-3-methyl-2-oxiranyl]methyl]-1H-1,2,4-triazole
  • Efinaconazole Epoxy Impurity
  • Efinaconazole Impurity 2
  • Efinaconazole Related Impurity
  • 1H-1,2,4-Triazole, 1-[[(2R,3R)-2-(2,4-difluorophenyl)-3-methyl-2-oxiranyl]methyl]-
  • 1-(((2R,3R)-2-(2,4-Difluorophenyl)-3-methyloxiran-2-yl)methyl)-1H-1,2,4-triazole (Efinaconazole Impurity)
  • 135270-13-2