5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride

Product Name: 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
CAS No.: 1123491-15-5
Chemical Name: 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride
Synonyms: DMPQ (hydrochloride);DMPQ dihydrochloride, PDGFR beta inhibitor
CBNumber: CB72750577
Molecular Formula: C16H16Cl2N2O2
Formula Weight: 339.21644
MOL File: 1123491-15-5.mol

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5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride Property

storage temp.: room temp
solubility: H2O: >10mg/mL
form: powder
color: white to beige
Water Solubility: Soluble to 100 mM in water
InChI: 1S/C16H14N2O2.2ClH/c1-19-13-8-15-14(16(9-13)20-2)7-12(10-18-15)11-3-5-17-6-4-11;;/h3-10H,1-2H3;2*1H
InChIKey: YBBAOKYVJCNJIV-UHFFFAOYSA-N
SMILES: Cl.Cl.COc1cc(OC)c2cc(cnc2c1)-c3ccncc3

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
Storage Class: 11 - Combustible Solids
Hazard Classifications: Acute Tox. 4 Oral

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: SML0334
Product name: DMPQ dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $58.42
Updated: 2025/07/31

Sigma-Aldrich

Product number: SML0334
Product name: DMPQ dihydrochloride
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $458
Updated: 2023/06/20

Cayman Chemical

Product number: 17551
Product name: DMPQ (hydrochloride)
Purity: ≥98%
Packaging: 1mg
Price: $32
Updated: 2024/03/01

Cayman Chemical

Product number: 17551
Product name: DMPQ (hydrochloride)
Purity: ≥98%
Packaging: 5mg
Price: $93
Updated: 2024/03/01

Cayman Chemical

Product number: 17551
Product name: DMPQ (hydrochloride)
Purity: ≥98%
Packaging: 10mg
Price: $120
Updated: 2024/03/01

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5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride Chemical Properties,Usage,Production

Uses

DMPQ dihydrochloride is a selective an a potent inhibitor of human platelet-derived growth factor receptor β (PDGFRβ).

Biological Activity

DMPQ is a potent selective inhibitor of human vascular beta-type platelet derived growth factor receptor tyrosine kinase (PDGFR) with IC50 = 80 nM. It is > 100-fold selective over EGFR, erbB2, p56, protein kinase A and protein kinase C.

storage

Store at RT

5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

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5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochloride Suppliers

China 32 United Kingdom 1 United States 6 Global 39

Shanghai YuanYe Biotechnology Co., Ltd.

Tel: 021-61312847; 18021002903
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TargetMol Chemicals Inc.

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Country: United States
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Career Henan Chemica Co

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Advantage: 58

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ShangHai ChuanQian Chemcial Technique Centre

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Hubei Xinyang Medical Technology Co., Ltd

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Energy Chemical

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MedBioPharmaceutical Technology Inc

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cjbscvictory

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1123491-15-5, 5,7-Dimethoxy-3-(4-pyridinyl)quinoline dihydrochlorideRelated Search:

5,7-DIMETHOXY-3-(4-PYRIDINYL)QUINOLINE DIHYDROCHLORIDE

DMPQ (hydrochloride)

DMPQ dihydrochloride, PDGFR beta inhibitor

1123491-15-5