Compound 2

Product Name: Compound 2
CAS No.: 281209-71-0
Chemical Name: Compound 2
Synonyms: 113683;Compound 2;GLP-1R agonist;GLP1-agonist-2;GLP-1R agonist DMB;GLP-1R agonist DMB-DMB;GLP-1R agonist >=98% (HPLC);GLP1R Agonist DMB,GLP 1R Agonist DMB;GLP-1R Agonist DMB（GLP-1R agonist 2 ）;Glucagon-Like Peptide 1 Receptor Agonist
CBNumber: CB72751004
Molecular Formula: C13H15Cl2N3O2S
Formula Weight: 348.25
MOL File: 281209-71-0.mol

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Compound 2 Property

Boiling point:: 535.2±50.0 °C(Predicted)
Density: 1.423±0.06 g/cm3(Predicted)
storage temp.: 2-8°C
solubility: DMSO: ≥10mg/mL
pka: -0.94±0.59(Predicted)
form: Yellow solid
color: light brown-yellow
InChI: 1S/C13H15Cl2N3O2S/c1-13(2,3)18-11-12(21(4,19)20)17-10-6-8(15)7(14)5-9(10)16-11/h5-6H,1-4H3,(H,16,18)
InChIKey: GNZCSGYHILBXLL-UHFFFAOYSA-N
SMILES: [S](=O)(=O)(C)c1nc2c(nc1NC(C)(C)C)cc(c(c2)Cl)Cl

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Safety

Hazard Codes: Xn
Risk Statements: 22
WGK Germany: 3
Storage Class: 11 - Combustible Solids

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Hazard and Precautionary Statements (GHS)

Symbol(GHS)

Signal word

Warning

Hazard statements

H302Harmful if swallowed

Precautionary statements

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P270Do not eat, drink or smoke when using this product.

P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.

P330Rinse mouth.

P501Dispose of contents/container to..…

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N-Bromosuccinimide Price

Sigma-Aldrich

Product number: G8048
Product name: GLP-1R agonist
Purity: ≥98% (HPLC)
Packaging: 5mg
Price: $243
Updated: 2026/03/19

Cayman Chemical

Product number: 29678
Product name: GLP-1R Agonist DMB
Packaging: 1mg
Price: $44
Updated: 2024/03/01

Cayman Chemical

Product number: 29678
Product name: GLP-1R Agonist DMB
Packaging: 25mg
Price: $849
Updated: 2024/03/01

Sigma-Aldrich

Product number: G8048
Product name: GLP-1R agonist
Purity: ≥98% (HPLC)
Packaging: 25mg
Price: $974
Updated: 2026/03/19

Cayman Chemical

Product number: 29678
Product name: GLP-1R Agonist DMB
Packaging: 5mg
Price: $202
Updated: 2024/03/01

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Compound 2 Chemical Properties,Usage,Production

Uses

GLP-1R agonist 2 (compound 2) is an effective GLP-1R agonist that exerts its activating effect by forming hydrogen bonds with the Tyr42, Cys71, and Ser84 residues of GLP-1R. GLP-1R agonist 2 has the potential for research in metabolic diseases such as type 2 diabetes and obesity[1].

General Description

Glucagon-like peptide-1 receptor (GLP-1R) agonist is a potential oral drug for modulating glucagon-like peptide (GLP)-1 in diabetic patients. GLP-1R agonists play a key role in lowering glycated hemoglobin levels. It improves glycemic control and maintenance of body weight.

Biochem/physiol Actions

GLP-1R is a small molecule GLP-1 receptor agonist. GLP-1 receptor signaling is a predominant mechanism for regulating glucose homeostasis. This compound represents a unique non-peptide tool for studying the role of GLP-1 in both in vivo and in vitro diabetes and obesity models.

References

[1] Girdhar K, et al. Novel insights into the dynamics behavior of glucagon-like peptide-1 receptor with its small molecule agonists. J Biomol Struct Dyn. 2019 Sep;37(15):3976-3986. DOI:10.1080/07391102.2018.1532818
[2] Knudsen LB, et al. Small-molecule agonists for the glucagon-like peptide 1 receptor. Proc Natl Acad Sci U S A. 2007 Jan 16;104(3):937-42. DOI:10.1073/pnas.0605701104

Compound 2 Preparation Products And Raw materials

Raw materials

Preparation Products

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Compound 2 Suppliers

China 42 United States 6 Global 48

ChemShuttle, Inc.

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Bide Pharmatech Ltd.

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Country: China
ProdList: 39999
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Sigma-Aldrich

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Shanghai GaoDao Pharmaceutical Co., Ltd.

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Shanghai EFE Biological Technology Co., Ltd.

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Shanghai YuanYe Biotechnology Co., Ltd.

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ShangHai Biochempartner Co.,Ltd

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Shanghai Hongye Biotechnology Co. Ltd

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Lanzhou Kangyuxin Biotechnology Co., Ltd.

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Email: sales@kyxpharma.com
Country: China
ProdList: 3391
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281209-71-0, Compound 2Related Search:

Glucagon-Like Peptide 1 Receptor Agonist - CAS 281209-71-0 - Calbiochem

113683

Glucagon-Like Peptide 1 Receptor Agonist

2-Quinoxalinamine, 6,7-dichloro-N-(1,1-dimethylethyl)-3-(methylsulfonyl)-

6,7-dichloro-2-methylsulfonyl-3-N-tert-butylaminoquinoxaline (DMB)

Compound 2

GLP-1R agonist

GLP-1R agonist DMB

N-(tert-butyl)-6,7-dichloro-3-(methylsulfonyl)quinoxalin-2-amine

GLP-1R agonist >=98% (HPLC)

GLP-1R agonist DMB-DMB

GLP1-agonist-2

GLP1R Agonist DMB,GLP 1R Agonist DMB

GLP-1R Agonist DMB（GLP-1R agonist 2 ）

281209-71-0