AKOS B019512
- Product Name
- AKOS B019512
- CAS No.
- 5775-82-6
- Chemical Name
- AKOS B019512
- Synonyms
- AKOS B019512;ART-CHEM-BB B019512;TIMTEC-BB SBB005613;4-Bromo-1,3-dimethylpyrazole;4-Bromo-1,3-dimethyl-1H-pyrazole;1H-Pyrazole, 4-bromo-1,3-dimethyl-;4-bromo-1,3-dimethyl-1H-pyrazole(SALTDATA: FREE)
- CBNumber
- CB7287101
- Molecular Formula
- C5H7BrN2
- Formula Weight
- 175.03
- MOL File
- Mol file
AKOS B019512 Property
- Boiling point:
- 100 °C(Press: 30 Torr)
- Density
- 1.487 g/mL at 25 °C
- refractive index
- 1.5214 (estimate)
- Flash point:
- 103 °C
- storage temp.
- 2-8°C
- form
- liquid
- pka
- 0.68±0.10(Predicted)
- Appearance
- Colorless to light yellow Liquid
- InChI
- InChI=1S/C5H7BrN2/c1-4-5(6)3-8(2)7-4/h3H,1-2H3
- InChIKey
- UESOBPUTZLYSGI-UHFFFAOYSA-N
- SMILES
- N1(C)C=C(Br)C(C)=N1
Hazard and Precautionary Statements (GHS)
- Symbol(GHS)
-
- Signal word
- Warning
- Hazard statements
-
H302Harmful if swallowed
H315Causes skin irritation
H319Causes serious eye irritation
H335May cause respiratory irritation
- Precautionary statements
-
P261Avoid breathing dust/fume/gas/mist/vapours/spray.
P301+P312IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P302+P352IF ON SKIN: wash with plenty of soap and water.
P304+P340IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
N-Bromosuccinimide Price
- Product number
- B691718
- Product name
- 4-Bromo-1,3-dimethylpyrazole
- Packaging
- 500mg
- Price
- $65
- Updated
- 2021/12/16
- Product number
- 030917
- Product name
- 4-Bromo-1,3-dimethyl-1H-pyrazole
- Purity
- 95+%
- Packaging
- 1g
- Price
- $23
- Updated
- 2021/12/16
- Product number
- B12562
- Product name
- 4-Bromo-1,3-dimethyl-1H-Pyrazole
- Purity
- 95%
- Packaging
- 1g
- Price
- $25
- Updated
- 2021/12/16
- Product number
- OR910091
- Product name
- 4-Bromo-1,3-dimethylpyrazole
- Purity
- 95%
- Packaging
- 1g
- Price
- $70
- Updated
- 2021/12/16
- Product number
- V6734
- Product name
- 4-Bromo-1,3-dimethylpyrazole
- Packaging
- 250mg
- Price
- $73
- Updated
- 2021/12/16
AKOS B019512 Chemical Properties,Usage,Production
Chemical Properties
White solid
Synthesis
694-48-4
5775-82-6
General procedure for the synthesis of 4-bromo-1,3-dimethyl-1H-pyrazole from 1,3-dimethyl-1H-pyrazole: Bromine (2.0 mL, 40.80 mmol) was added slowly and dropwise to a solution of 1,3-dimethyl-1H-pyrazole (3.92 g, 40.80 mmol) in acetic acid (10 mL) at room temperature. The reaction mixture was heated to 70 °C and maintained for 1 hour. Upon completion of the reaction, it was cooled to room temperature and concentrated under vacuum to give the crude product. The pH of the crude product was adjusted with saturated sodium carbonate solution to 7~8. Subsequently, extraction was carried out with ethyl acetate (50 mL x 3), the organic phases were combined and dried over anhydrous sodium sulfate. After filtration, the filtrate was concentrated under vacuum to give the residue. The residue was purified by column chromatography (eluent: ethyl acetate/petroleum ether = 1/6 to 1/4) to afford the target compound 4-bromo-1,3-dimethyl-1H-pyrazole (3.30 g, yield: 46%) as an oil. The product was detected by ESI-MS and showed (M + H)+ peak located at 175.1. 1H NMR (400 MHz, CDCl3) data were as follows: δ 7.30 (s, 1H), 3.83 (s, 3H), 2.23 (s, 3H).
References
[1] J. Gen. Chem. USSR (Engl. Transl.), 1980, vol. 50, # 9, p. 1714 - 1716
[2] Zhurnal Obshchei Khimii, 1980, vol. 50, # 9, p. 2116 - 2119
[3] Patent: WO2015/89327, 2015, A1. Location in patent: Paragraph 0296
[4] Chemische Berichte, 1926, vol. 59, p. 606,1296
AKOS B019512 Preparation Products And Raw materials
Raw materials
Preparation Products
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