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TRIBUTYL(1-ETHOXYVINYL)TIN

Reaction
Product Name
TRIBUTYL(1-ETHOXYVINYL)TIN
CAS No.
97674-02-7
Chemical Name
TRIBUTYL(1-ETHOXYVINYL)TIN
Synonyms
Tributyl(1-ethoxyvinyl)stannane;SKL1024;(1-ethoxyvinyL;(1-ethoxyvinyl)tributyltin;Tributyl(1-ethoxyvinyl)tin(IV);ETHOXYVINYL TRIBUTYL TIN;tributyl ethoxyvinyl tin;TRIBUTYL(1-ETHOXYVINYL)TIN;1-ETHOXYVINYL-TRI-N-BUTYLTIN;Tri-n-butyl(1-ethoxyvinyl)tin
CBNumber
CB7292048
Molecular Formula
C16H34OSn
Formula Weight
361.15
MOL File
97674-02-7.mol
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TRIBUTYL(1-ETHOXYVINYL)TIN Property

Melting point:
<0°C
Boiling point:
85-86 °C0.1 mm Hg(lit.)
Density 
1.069 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.476(lit.)
Flash point:
>230 °F
storage temp. 
2-8°C
solubility 
Choroform (Slightly), Ethyl Acetate (Slightly)
form 
liquid
Specific Gravity
1.069
color 
colorless
Sensitive 
Moisture Sensitive
InChI
InChI=1S/C4H7O.3C4H9.Sn/c1-3-5-4-2;3*1-3-4-2;/h1,4H2,2H3;3*1,3-4H2,2H3;
InChIKey
HGXJOXHYPGNVNK-UHFFFAOYSA-N
SMILES
[Sn](CCCC)(CCCC)(CCCC)C(OCC)=C
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Safety

Hazard Codes 
T,N
Risk Statements 
21-25-36/38-48/23/25-50/53
Safety Statements 
35-36/37/39-45-60-61
RIDADR 
UN 2788 6.1/PG 3
WGK Germany 
3
TSCA 
No
HazardClass 
6.1(b)
PackingGroup 
III
HS Code 
29319090
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Danger
Hazard statements

H301Toxic if swalloed

H315Causes skin irritation

H319Causes serious eye irritation

H372Causes damage to organs through prolonged or repeated exposure

H400Very toxic to aquatic life

Precautionary statements

P273Avoid release to the environment.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

P314Get medical advice/attention if you feel unwell.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
275123
Product name
Tributyl(1-ethoxyvinyl)tin
Purity
97%
Packaging
1g
Price
$30.59
Updated
2025/07/31
Sigma-Aldrich
Product number
275123
Product name
Tributyl(1-ethoxyvinyl)tin
Purity
97%
Packaging
5g
Price
$153
Updated
2025/07/31
Strem Chemicals
Product number
50-3015
Product name
Tributyl(1-ethoxyvinyl)tin, 97%
Packaging
1g
Price
$50
Updated
2024/03/01
Strem Chemicals
Product number
50-3015
Product name
Tributyl(1-ethoxyvinyl)tin, 97%
Packaging
5g
Price
$200
Updated
2024/03/01
Sigma-Aldrich
Product number
275123
Product name
Tributyl(1-ethoxyvinyl)tin
Purity
97%
Packaging
25g
Price
$710
Updated
2025/07/31
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TRIBUTYL(1-ETHOXYVINYL)TIN Chemical Properties,Usage,Production

Reaction

Versatile tin reagent used for the introduction of a 1-ethoxyvinyl group via a Stille cross-coupling reaction, (palladium-catalyzed coupling of an organohalide (or pseudohalide) with an organotin compound).

Chemical Properties

Clear colorless liquid

Uses

Electrophilic methyl ketone equivalent used in a recent synthesis of a 13-oxophorbine (chlorophyll) from the corresponding 13-bromochlorin.

General Description

This vinylstannane undergoes Stille coupling with a vinyl triflate, giving, after hydrolysis, an α,β?unsaturated ketone, thus acting as an acetyl anion equivalent.

Synthesis

1461-22-9

109-92-2

97674-02-7

Under nitrogen protection, 112 g of potassium tert-butoxide (1.0 mmol), and 139.2 g of tetramethylethylenediamine (1.2 mmol) were added to 1000 mL of anhydrous hexane and cooled to -30 °C. A 400 mL hexane solution of n-butyllithium (2.5 M) was slowly added dropwise, and the reaction was maintained at -30 °C for 1.5 h after completion of the dropwise addition, followed by cooling to -40 °C. 108 g of vinyl ether (1.5 mmol) was dissolved in 200 mL of anhydrous tetrahydrofuran and slowly added dropwise to the above mixed solution, maintained at -40 °C for 0.5 h. After the reaction was completed, it was warmed up to -20 °C to continue the reaction for 1 h. It was subsequently cooled to -78 °C. 227.9 g of tributyltin chloride (0.7 mmol) was dissolved in 500 mL of anhydrous tetrahydrofuran and slowly added dropwise to the reaction mixture, maintained at -78 °C for 2 hours, followed by natural warming and stirring for 8 hours. Upon completion of the reaction, the reaction was quenched by slow dropwise addition of 400 mL of saturated ammonium chloride solution, filtered and the organic phase was separated. The aqueous phase was extracted with hexane (500 mL x 3), the organic layers were combined and washed sequentially with water (500 mL x 3) and saturated brine (500 mL x 3). The organic phase was dried with 100 g of anhydrous sodium sulfate, filtered and concentrated under reduced pressure to constant weight to give 228.7 g of tributyl(1-ethoxyvinyl)tin crude product. The crude product was subjected to distillation under vacuum and the fraction at 75 °C-85 °C at 0.005 mmHg was collected to give 205 g of colorless transparent liquid in 81.03% yield.

References

[1] Patent: CN106046043, 2016, A. Location in patent: Paragraph 0016; 0017
[2] Organic Process Research and Development, 2014, vol. 18, # 8, p. 993 - 1001

TRIBUTYL(1-ETHOXYVINYL)TIN Preparation Products And Raw materials

Raw materials

Preparation Products

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TRIBUTYL(1-ETHOXYVINYL)TIN Suppliers

Birdo (Shanghai) Medical Technology Co., Ltd.
Tel
021-58099077-8041 18601625411
Email
sales@birdotech.com
Country
China
ProdList
9764
Advantage
58
Shanghai Arbor Chemical Co., Ltd.
Tel
021-60451683 15021268886
Fax
+86-21-60451682
Email
sales@arborchemical.com
Country
China
ProdList
896
Advantage
55
Established by Hangzhou Boman Biochem Tech Co., Ltd
Tel
13588048971
Email
sales@bomanbiochem.com
Country
China
ProdList
476
Advantage
58
Chengdu Aslee Biopharmaceuticals, Inc
Tel
028-85305008 02885305008
Fax
4000210878-186
Email
2306208234@qq.com
Country
China
ProdList
1006
Advantage
50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd.
Tel
025-66113011 17798518460
Fax
(1)02557626880
Email
cfzhang@aikonchem.com
Country
China
ProdList
19913
Advantage
55
Aikon International Limited
Tel
025-66061636 18013972705
Fax
(3)02557626880
Email
qqyang@aikonchem.com
Country
China
ProdList
15814
Advantage
58
Shanghai Boyle Chemical Co., Ltd.
Tel
Fax
86-21-57758967
Email
sales@boylechem.com
Country
China
ProdList
2922
Advantage
55
J & K SCIENTIFIC LTD.
Tel
18210857532; 18210857532
Fax
86-10-82849933
Email
jkinfo@jkchemical.com
Country
China
ProdList
96815
Advantage
76
Meryer (Shanghai) Chemical Technology Co., Ltd.
Tel
4006356688 18621169109
Fax
86-21-61259102
Email
market03@meryer.com
Country
China
ProdList
40228
Advantage
62
Alfa Aesar
Tel
400-6106006
Fax
021-67582001/03/05
Email
saleschina@alfa-asia.com
Country
China
ProdList
30123
Advantage
84
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View Lastest Price from TRIBUTYL(1-ETHOXYVINYL)TIN manufacturers

Sach biotech Co.,Ltd
Product
Tributyl(1-ethoxyvinyl)stannane 97674-02-7
Price
US $450.00-430.00/kg
Min. Order
1kg
Purity
98%
Supply Ability
5mt
Release date
2025-06-11
Hebei Chuanghai Biotechnology Co., Ltd
Product
TRIBUTYL(1-ETHOXYVINYL)TIN 97674-02-7
Price
US $10.00/KG
Min. Order
1KG
Purity
99%
Supply Ability
10 mt
Release date
2024-12-10

97674-02-7, TRIBUTYL(1-ETHOXYVINYL)TINRelated Search:


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