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3-METHOXYPHENETHYL ALCOHOL

Product Name
3-METHOXYPHENETHYL ALCOHOL
CAS No.
5020-41-7
Chemical Name
3-METHOXYPHENETHYL ALCOHOL
Synonyms
m-Methoxyphenylethanol;3-Methoxybenzeneethanol;2-(meta-anisyl) ethanol;3-(2-Hydroxyethyl)anisole;m-Methoxyphenethyl alcohol;2-(3-METHOXYPHENYL)ETHANOL;3-METHOXYPHENETHYL ALCOHOL;Benzeneethanol, 3-methoxy-;3-Methyoxyphenethyl alcohol;Phenethyl alcohol, m-methoxy-
CBNumber
CB7298459
Molecular Formula
C9H12O2
Formula Weight
152.19
MOL File
5020-41-7.mol
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3-METHOXYPHENETHYL ALCOHOL Property

Boiling point:
141-143 °C12 mm Hg(lit.)
Density 
1.075 g/mL at 25 °C(lit.)
refractive index 
n20/D 1.538(lit.)
Flash point:
>230 °F
storage temp. 
Sealed in dry,Room Temperature
solubility 
Chloroform
pka
14.89±0.10(Predicted)
form 
Liquid
color 
Clear colorless to pale yellow
BRN 
1863114
LogP
1.555 (est)
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Safety

Safety Statements 
24/25
WGK Germany 
3
HS Code 
29094990
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
187933
Product name
3-Methoxyphenethyl alcohol
Purity
97%
Packaging
1g
Price
$28.6
Updated
2025/07/31
Sigma-Aldrich
Product number
187933
Product name
3-Methoxyphenethyl alcohol
Purity
97%
Packaging
5g
Price
$152
Updated
2023/06/20
TCI Chemical
Product number
M2658
Product name
3-Methoxyphenethyl Alcohol
Purity
>98.0%(GC)
Packaging
1g
Price
$55
Updated
2025/07/31
TCI Chemical
Product number
M2658
Product name
3-Methoxyphenethyl Alcohol
Purity
>98.0%(GC)
Packaging
5g
Price
$184
Updated
2025/07/31
Sigma-Aldrich
Product number
187933
Product name
3-Methoxyphenethyl alcohol
Purity
97%
Packaging
25g
Price
$268
Updated
2023/06/20
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3-METHOXYPHENETHYL ALCOHOL Chemical Properties,Usage,Production

Chemical Properties

Clear colorless to pale yellow liquid

Uses

A metabolite of Dopamine analogs

Uses

3-Methoxyphenethyl alcohol was used as starting reagent during the synthesis of 3-methoxy-2,6-dimethyl- phenethyl alcohol.

Definition

ChEBI: 3-Methoxyphenethyl alcohol is a member of methoxybenzenes.

Synthesis

1798-09-0

5020-41-7

The general procedure for the synthesis of 2-(3-methoxyphenyl)ethanol from 3-methoxyphenylacetic acid is as follows: first, 3-methoxyphenylacetic acid (75.09 mg, 0.5 mmol), rhenium complex (7.07 mg, 0.010 mmol), and potassium tetraphenylborate (17.92 mg, 0.05 mmol) were added to dry 25 mL glass tubes equipped with stirring bars . The mixture was transferred to an autoclave and dehydrated toluene (4.0 mL) was added under argon protection. Subsequently, the argon gas in the autoclave was replaced with hydrogen, a process accomplished through a stainless steel tube connected to a hydrogen cylinder and repeated five times to ensure complete replacement. The hydrogen pressure was set to 4 MPa, and the autoclave was placed in a thermostatic bath at 180°C for 12 hours. At the end of the reaction, the autoclave was cooled to room temperature and the hydrogen pressure was slowly released. After removing the solvent, the reaction products were analyzed by 1H NMR using homotrimethylbenzene (60.1 mg, 0.5 mmol) as an internal standard, and the yields of 2-(3-methoxyphenyl)ethanol and 3-methoxyphenylacetic acid were obtained as 98% and 1%, respectively. For different substrates and hydrogenation conditions, the specific conditions were adjusted with reference to those in Tables 7-9, where entries 19-26 used tetrahydrofuran (THF) as solvent. The experimental results are detailed in Tables 7 to 9.

References

[1] Journal of Organic Chemistry, 1994, vol. 59, # 14, p. 3933 - 3938
[2] Tetrahedron, 2006, vol. 62, # 29, p. 7056 - 7070
[3] Tetrahedron Letters, 2016, vol. 57, # 35, p. 3942 - 3944
[4] Canadian Journal of Chemistry, 2009, vol. 87, # 5, p. 650 - 661
[5] Advanced Synthesis and Catalysis, 2016, vol. 358, # 3, p. 452 - 458

3-METHOXYPHENETHYL ALCOHOL Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from 3-METHOXYPHENETHYL ALCOHOL manufacturers

Career Henan Chemical Co
Product
3-METHOXYPHENETHYL ALCOHOL 5020-41-7
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-08

5020-41-7, 3-METHOXYPHENETHYL ALCOHOLRelated Search:


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