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RES-701-1

Product Name
RES-701-1
CAS No.
151308-34-8
Chemical Name
RES-701-1
Synonyms
RES-701-1;RES-701-1 USP/EP/BP;cyclo(gly-asn-trp-his-gly-thr-ala-pro-*B-asp)-thr;GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP;GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP;CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH;L-Tryptophan, glycyl-L-asparaginyl-L-tryptophyl-L-histidylglycyl-L-threonyl-L-alanyl-L-prolyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-phenylalanyl-L-asparaginyl-L-tyrosyl-L-tyrosyl-, (9→1)-lactam
CBNumber
CB7301326
Molecular Formula
C103H115N23O23
Formula Weight
2043.16
MOL File
151308-34-8.mol
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RES-701-1 Property

Density 
1.50±0.1 g/cm3(Predicted)
storage temp. 
−20°C
pka
3.35±0.10(Predicted)
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Safety

Safety Statements 
22-24/25
WGK Germany 
3
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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

Biosynth Carbosynth
Product number
FC108692
Product name
Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH
Packaging
50ug
Price
$131
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC108692
Product name
Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH
Packaging
100ug
Price
$227
Updated
2021/12/16
Biosynth Carbosynth
Product number
FC108692
Product name
Cyclo(-Gly-Asn-Trp-His-Gly-Thr-Ala-Pro-Asp)-Trp-Phe-Phe-Asn-Tyr-Tyr-Trp-OH
Packaging
250ug
Price
$452.5
Updated
2021/12/16
Biorbyt Ltd
Product number
orb372785
Product name
RES-701-1
Purity
> 95%
Packaging
1mg
Price
$467.5
Updated
2021/12/16
American Custom Chemicals Corporation
Product number
PEP0004786
Product name
CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH
Purity
95.00%
Packaging
5MG
Price
$500.79
Updated
2021/12/16
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RES-701-1 Chemical Properties,Usage,Production

Uses

RES-701-1 is a cyclic peptide composed of 16 common L-amino acids, acting as a specific antagonist for the ETB receptor. RES-701-1 can inhibit the binding of 125I-ET-1 (125I-labeled Endothelin (ET)-1) to the ETB receptor, with an IC50 value of 10 nM[1][2].

IC 50

ETB: 10 nM (IC50)

References

[1] Tanaka T, et al. RES-701-1, a novel, potent, endothelin type B receptor-selective antagonist of microbial origin. Mol Pharmacol. 1994 Apr;45(4):724-30. PMID:8183252
[2] Yamasaki M, et al. RES-701-1, a novel and selective endothelin type B receptor antagonist produced by Streptomyces sp. RE-701 II. Determination of the primary sequence[J]. The Journal of Antibiotics, 1994, 47(3): 276-280. DOI:10.7164/antibiotics.47.276

RES-701-1 Preparation Products And Raw materials

Raw materials

Preparation Products

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RES-701-1 Suppliers

China 66 Japan 1 Switzerland 2 United Kingdom 1 United States 7 Global 77
Adachibio Inc.
Tel
+81-8027837258; +8108027837258
Fax
0081-80278372055
Email
sales@adachibio.com
Country
Japan
ProdList
992
Advantage
58

151308-34-8, RES-701-1Related Search:

RES-701-3 RES 701-4 RES 701-1 SODIUM SALT RES 701-2 RES-701-1 H-PHE-TRP-OH AC-PHE-TRP-OH H-TYR-TRP-OH

  • CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP
  • CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-BETA-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH
  • RES-701-1
  • cyclo(gly-asn-trp-his-gly-thr-ala-pro-*B-asp)-thr
  • GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP
  • GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH
  • CYCLO(-GLY-ASN-TRP-HIS-GLY-THR-ALA-PRO-ASP)-TRP-PHE-PHE-ASN-TYR-TYR-TRP-OH
  • L-Tryptophan, glycyl-L-asparaginyl-L-tryptophyl-L-histidylglycyl-L-threonyl-L-alanyl-L-prolyl-L-α-aspartyl-L-tryptophyl-L-phenylalanyl-L-phenylalanyl-L-asparaginyl-L-tyrosyl-L-tyrosyl-, (9→1)-lactam
  • RES-701-1 USP/EP/BP
  • 151308-34-8
  • C103H115N23O23