ChemicalBook > CAS DataBase List > N-Succinimidyl-N-methylcarbamate

N-Succinimidyl-N-methylcarbamate

Product Name
N-Succinimidyl-N-methylcarbamate
CAS No.
18342-66-0
Chemical Name
N-Succinimidyl-N-methylcarbamate
Synonyms
SuO-NM;methyl isocyanate substitute;N-Succinimidyl-N-methylcarbame;N-Succinimidyl Methylcarbamate;N-Succinimidyl-N-methylcarbama;N-SUCCINIMDYL-N-METHYLCARBAMATE;N-SUCCINIMIDYL-N-METHYLCARBAMATE;2,5-dioxopyrrolidin-1-yl MethylcarbaMate;Methylcarbamic Acid N-Succinimidyl Ester;N-Succinimidyl N-methylcarbamate >=97.0% (N)
CBNumber
CB7301533
Molecular Formula
C6H8N2O4
Formula Weight
172.14
MOL File
18342-66-0.mol
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N-Succinimidyl-N-methylcarbamate Property

Melting point:
148-153 °C
Density 
1.41±0.1 g/cm3(Predicted)
storage temp. 
2-8°C
solubility 
Dichloromethane (Slightly), DMSO (Slightly)
pka
11.00±0.46(Predicted)
form 
Solid
color 
White to Off-White
Water Solubility 
Slightly soluble in water.
Sensitive 
Moisture Sensitive
BRN 
1531863
CAS DataBase Reference
18342-66-0(CAS DataBase Reference)
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Safety

Hazard Codes 
Xi
Risk Statements 
36/37/38
Safety Statements 
26-36
WGK Germany 
3
F 
10-21
HS Code 
2928.00.5000
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P264Wash hands thoroughly after handling.

P264Wash skin thouroughly after handling.

P271Use only outdoors or in a well-ventilated area.

P280Wear protective gloves/protective clothing/eye protection/face protection.

P302+P352IF ON SKIN: wash with plenty of soap and water.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Sigma-Aldrich
Product number
66181
Product name
N-Succinimidyl N-methylcarbamate
Purity
≥97.0% (N)
Packaging
5g
Price
$312
Updated
2024/03/01
Sigma-Aldrich
Product number
66181
Product name
N-Succinimidyl N-methylcarbamate
Purity
≥97.0% (N)
Packaging
25g
Price
$638
Updated
2023/06/20
TCI Chemical
Product number
U0108
Product name
N-Succinimidyl Methylcarbamate
Purity
>98.0%(N)
Packaging
1g
Price
$25
Updated
2024/03/01
TCI Chemical
Product number
U0108
Product name
N-Succinimidyl Methylcarbamate
Purity
>98.0%(N)
Packaging
5g
Price
$69
Updated
2024/03/01
Alfa Aesar
Product number
H63566
Product name
N-Succinimidyl N-methylcarbamate, 97%
Packaging
1g
Price
$36
Updated
2023/06/20
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N-Succinimidyl-N-methylcarbamate Chemical Properties,Usage,Production

Uses

N-Succinimidyl N-Methylcarbamate is used as a reagent in the synthesis of Argifin, a natural product chitinase inhibitor with chemotherapeutic potential. N-Succinimidyl N-Methylcarbamate is also used as a reagent in the preparation of 5-Amino-N1-methyl-1H-imidazole-1,4-dicarboxamide (A616300); a metabolite of Temozolomide (T017775) which is an imidazotetrazine alkylating agent and antineoplastic.

Definition

ChEBI: N-succinimidyl N-methylcarbamate is a member of the class of pyrrolidinones that is N-hydroxysuccinimide in which the hydroxyl hydrogen is replaced by a methylcarbamoyl group. It has a role as an apoptosis inducer. It is a carbamate ester, a dicarboximide, a pyrrolidinone and a N-hydroxysuccinimide ester. It is functionally related to a succinimide.

N-Succinimidyl-N-methylcarbamate Preparation Products And Raw materials

Raw materials

Preparation Products

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N-Succinimidyl-N-methylcarbamate Suppliers

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View Lastest Price from N-Succinimidyl-N-methylcarbamate manufacturers

Henan Aochuang Chemical Co.,Ltd.
Product
N-Succinimidyl-N-methylcarbamate 18342-66-0
Price
US $0.00-0.00/KG
Min. Order
1KG
Purity
98%
Supply Ability
1ton
Release date
2022-09-26
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Succinimidyl-N-Methylcarbamate 18342-66-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-10
Zhuozhou Wenxi import and Export Co., Ltd
Product
N-Succinimidyl-N-Methylcarbamate 18342-66-0
Price
US $15.00-10.00/KG
Min. Order
1KG
Purity
99%+ HPLC
Supply Ability
Monthly supply of 1 ton
Release date
2021-07-08

18342-66-0, N-Succinimidyl-N-methylcarbamateRelated Search:

POLYURETHANE Methyl anthranilate Urethane Dithiooxamide 4-Aminobenzoic acid 6-Aminoquinolyl-N-hydroxysuccinimidylcarbamate Anthranilic acid TERT-BUTYL N-SUCCINIMIDYL N,N'-TRIMETHYLENEDICARBAMATE TERT-BUTYL N-SUCCINIMIDYL N,N'-(1,4-PHENYLENE)DICARBAMATE TERT-BUTYL-N-SUCCINIMIDYL N N'-ETHYLENE- N-SucciniMidoxycarbonyl-β-alanine N-SucciniMidyl Ester TERT-BUTYL N-SUCCINIMIDYL N,N'-HEXAMETHYLENEDICARBAMATE CARBAMIC ACID, (2-CHLOROETHYL)NITROSO-, 2,5-DIOXO-1-PYRROLIDINYL ESTER TERT-BUTYL N-SUCCINIMIDYL N,N'-TETRAMETHYLENEDICARBAMATE N-Succinimidyl-N-methylcarbamate

  • 2,5-PYRROLIDINEDIONE, 1-[[(METHYLAMINO)CARBONYL]OXY]-
  • N-SUCCINIMDYL-N-METHYLCARBAMATE
  • N-SUCCINIMIDYL-N-METHYLCARBAMATE
  • N-Succinimidyl-N-methylcarbama
  • methyl isocyanate substitute
  • Methyl isocyanate substitute, MIC substitute
  • 2,5-dioxopyrrolidin-1-yl MethylcarbaMate
  • SuO-NM
  • N-Succinimidyl Methylcarbamate
  • N-Succinimidyl-N-methylcarbame
  • N-Succinimidyl N-methylcarbamate >=97.0% (N)
  • Methylcarbamic Acid N-Succinimidyl Ester
  • 1-[[(Methylamino)carbonyl]oxy]-2,5-pyrrolidinedione
  • 1-[(Methylcarbamoyl)oxy]-2,5-pyrrolidinedione
  • 18342-66-0
  • 8342-66-0
  • C6H8N2O4
  • Synthetic Reagents
  • Coupling
  • Active Esters/Additives
  • Norbornene Derivatives
  • Medical Intermediates