3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE

Product Name: 3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE
CAS No.: 5466-89-7
Chemical Name: 3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE
Synonyms: U-0521;U-0521,98+%;U0521,U 0521;3’,4’-dihydroxyisobutyrophenone;3’,4’-dihydroxy-isobutyrophenon;3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE;3',4'-Dihydroxy-α-methylpropiophenone;3’,4’-dihydroxy-2-methyl-propiophenon;1-(3,4-dihydroxyphenyl)-2-methyl-1-propanon;1-(3,4-Dihydroxyphenyl)-2-methylpropan-1-one
CBNumber: CB7304842
Molecular Formula: C10H12O3
Formula Weight: 180.2
MOL File: 5466-89-7.mol

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3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE Property

Melting point:: 79-81℃
Boiling point:: 372.2±27.0 °C(Predicted)
Density: 1.191±0.06 g/cm3(Predicted)
RTECS: NQ5605000
storage temp.: -20°C Freezer
solubility: Chloroform (Slightly), DMSO (Slightly), Ethyl Acetate (Slightly), Methanol (Slightly)
form: White solid.
pka: 8.77±0.31(Predicted)
color: Off-White to Pale Beige

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Hazard and Precautionary Statements (GHS)

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N-Bromosuccinimide Price

TRC

Product number: U850325
Product name: U-0521
Packaging: 100mg
Price: $340
Updated: 2021/12/16

TRC

Product number: U850325
Product name: U-0521
Packaging: 25mg
Price: $105
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000127
Product name: U-0521
Purity: 95.00%
Packaging: 20MG
Price: $453
Updated: 2021/12/16

American Custom Chemicals Corporation

Product number: INB0000127
Product name: U-0521
Purity: 95.00%
Packaging: 100MG
Price: $613
Updated: 2021/12/16

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3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE Chemical Properties,Usage,Production

Uses

U-0521 is an extraneuronal COMT uptake inhibitor.

Definition

ChEBI: U 0521 is a member of acetophenones.

in vivo

U-0521 (i.p.; 0-250 mg/kg; 10 min) inhibits COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity is obtained at 90 mg/kg and maximum inhibition of 90% is obtained at 250 mg/kg^[1].

Animal Model:	Male Sprague-Dawley rats (180-250 g)^[1]
Dosage:	0-250 mg/kg
Administration:	i.p.; 10 min
Result:	Inhibited COMT activity in a dose-dependent manner. 50% inhibition of enzyme activity was obtained at 90mg/kg and maximum inhibition of 90% was obtained at 250 mg/kg.

3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE Preparation Products And Raw materials

Raw materials

Preparation Products

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3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE Suppliers

China 26 Germany 1 United States 6 Global 33

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5466-89-7, 3',4'-DIHYDROXY-2-METHYLPROPIOPHENONERelated Search:

DONEPEZIL HYDROCHLORIDE Donepezil 2-((3,4-DIMETHOXYPHENYL)CARBONYL)INDANE-1,3-DIONE DONEPEZIL-13C3, HYDROCHLORIDE CORYCAVINE 3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE SIBIRICINE 6-HYDROXYSUMATROL CYCLOPENTYL-3,4-DIHYDROXYPHENYLKETONE 5,6-Diethoxy-2-((dimethylamino)methyl)-2,3-dihydro-1H-inden-1-one hydr ochloride (-)-YENHUSOMIDINE diethyl (3,4,5-trimethoxybenzoyl)malonate

1-(3,4-dihydroxyphenyl)-2-methyl-1-propanon

3’,4’-dihydroxy-2-methyl-propiophenon

3’,4’-dihydroxy-isobutyrophenon

3’,4’-dihydroxyisobutyrophenone

U-0521

3',4'-DIHYDROXY-2-METHYLPROPIOPHENONE

U-0521,98+%

1-(3,4-Dihydroxyphenyl)-2-methylpropan-1-one

3',4'-Dihydroxy-α-methylpropiophenone

1-Propanone, 1-(3,4-dihydroxyphenyl)-2-methyl-

U0521,U 0521

5466-89-7