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Voxelotor

Product Name
Voxelotor
CAS No.
1446321-46-5
Chemical Name
Voxelotor
Synonyms
GBT 440;GTx011;Hemoglobin Modulators-1;2-Hydroxy-6-{[2-(1-isopropyl-1H-pyrazol-5-yl)-3-pyridinyl]methoxy}benzaldehyde;2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde;Oxbryta);Voxelotor;2H7]-Voxelotor;GBT-440(Voxelotor);Voxelotor (GBT-440
CBNumber
CB73053893
Molecular Formula
C19H19N3O3
Formula Weight
337.37
MOL File
1446321-46-5.mol
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Voxelotor Property

Melting point:
95 - 97oC
Boiling point:
539.2±50.0 °C(Predicted)
Density 
1.23±0.1 g/cm3(Predicted)
storage temp. 
-20°C Freezer, Under inert atmosphere
solubility 
Chloroform (Slightly), DMSO (Slightly)
pka
7.67±0.10(Predicted)
form 
Solid
color 
White to Off-White
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Hazard and Precautionary Statements (GHS)

Symbol(GHS)
Signal word
Warning
Hazard statements

H302Harmful if swallowed

H315Causes skin irritation

H319Causes serious eye irritation

H335May cause respiratory irritation

Precautionary statements

P261Avoid breathing dust/fume/gas/mist/vapours/spray.

P305+P351+P338IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

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N-Bromosuccinimide Price

Cayman Chemical
Product number
23933
Product name
GBT-440
Purity
≥98%
Packaging
1mg
Price
$25
Updated
2024/03/01
Cayman Chemical
Product number
23933
Product name
GBT-440
Purity
≥98%
Packaging
5mg
Price
$75
Updated
2024/03/01
Cayman Chemical
Product number
23933
Product name
GBT-440
Purity
≥98%
Packaging
10mg
Price
$125
Updated
2024/03/01
Cayman Chemical
Product number
23933
Product name
GBT-440
Purity
≥98%
Packaging
25mg
Price
$219
Updated
2024/03/01
TRC
Product number
G268015
Product name
GBT440
Packaging
5mg
Price
$400
Updated
2021/12/16
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Voxelotor Chemical Properties,Usage,Production

Uses

GBT 440 is a potent allosteric effector of sickle cell hemoglobin (Hb) that increases the affinity of Hb for oxygen and inhibits its polymerization when subjected to hypoxic conditions.

Voxelotor Preparation Products And Raw materials

Raw materials

Preparation Products

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View Lastest Price from Voxelotor manufacturers

Shaanxi TNJONE Pharmaceutical Co., Ltd
Product
Voxelotor 1446321-46-5
Price
US $0.00/kg
Min. Order
1kg
Purity
99%
Supply Ability
20tons
Release date
2024-04-01
Henan Fengda Chemical Co., Ltd
Product
Voxelotor 1446321-46-5
Price
US $35.00-1.20/kg
Min. Order
1kg
Purity
99%
Supply Ability
g-kg-tons, free sample is available
Release date
2024-03-28
Career Henan Chemical Co
Product
Voxelotor 1446321-46-5
Price
US $6.68/KG
Min. Order
1KG
Purity
97%-99%
Supply Ability
1kg-1000kg
Release date
2020-01-08

1446321-46-5, VoxelotorRelated Search:


  • 2-hydroxy-6-([2-[1-(propan-2-yl)-1H-pyrazol-5-yl]pyridin-3-yl]methoxy)benzaldehyde
  • GBT 440
  • 2-Hydroxy-6-{[2-(1-isopropyl-1H-pyrazol-5-yl)-3-pyridinyl]methoxy}benzaldehyde
  • Hemoglobin Modulators-1
  • 2-hydroxy-6-((2-(1-isopropyl-1H-pyrazol-5-yl)pyridin-3-yl)methoxy)benzaldehyde
  • Voxelotor(GBT440, GTX011)
  • Voxelotor
  • Voxelotor, GBT-440, GBT 440, GBT440, GTx-011, GTx011, GTx 011
  • VOXELOTOR, GBT-440, GBT 440, GBT440, GTX-011, GTX011, GTX 011;
  • GTx011
  • GTX011;GTX011;GTX011
  • GBT-440(Voxelotor)
  • Benzaldehyde, 2-hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]-
  • Oxbryta)
  • Voxelotor (GBT-440
  • Voxelotor,GBT440,GTX011,Hemoglobin Modulators-1
  • 2H7]-Voxelotor
  • Lanreotide Impurity 33
  • 2-Hydroxy-6-[[2-[1-(1-methylethyl)-1H-pyrazol-5-yl]-3-pyridinyl]methoxy]benzaldehyde
  • 1446321-46-5
  • API